HsaINT0126522 @ hg19
Intron Retention
Gene
ENSG00000104368 | PLAT
Description
plasminogen activator, tissue [Source:HGNC Symbol;Acc:9051]
Coordinates
chr8:42042599-42045090:-
Coord C1 exon
chr8:42044916-42045090
Coord A exon
chr8:42042691-42044915
Coord C2 exon
chr8:42042599-42042690
Length
2225 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
3' ss Seq
TCCCTTGGCTGATTTTTCAGAAA
3' ss Score
7.3
Exon sequences
Seq C1 exon
ATACCAGGGCCACGTGCTACGAGGACCAGGGCATCAGCTACAGGGGCACGTGGAGCACAGCGGAGAGTGGCGCCGAGTGCACCAACTGGAACAGCAGCGCGTTGGCCCAGAAGCCCTACAGCGGGCGGAGGCCAGACGCCATCAGGCTGGGCCTGGGGAACCACAACTACTGCAG
Seq A exon
GTGAGGGCACATCCCCAAGGAGGGATTCCCCCTGTGAGAAGCTGCTACAGCTGGGGAAAGATTCTGTCAGATCCGTCAGGGTTCTCCCAAGAAACATAACCAATACAGGATGGATAGATGGATAGATGATAGACAGATAATAGATGATAGGTGATAGATGATAGATTGATAGATGATAGATGATAGGTGATAGATTAGATAAATAGATGATACATACATGATAGATAGATGATAAATAGACGGTAGATGGATGACAGATAGACAGATGATAGGTGATAGATAGATGATAGATTGATAGATGATTGATAGATAAATAGATGATAGATACATAGATGATAGATGGTAGATAGATGATAGATGGATAGATGATAGATGATAGGTGGTAGATGATAGACAGATGATTAGAAAGATAGATGATAGATACATAGATGATAGACACATAGATGATAGACAGATTGACAGATGATAGATGATTGATAGATGATTAAATAGATGATACATAGATGATAATGATAAATAGATGATAGATGATAGATGATAGGTGATAGATAGATTGATAGATGATAGAAGATTGATAGATGATAGATACATAGGTGATAGTAGATGTAAGATGATAGATGATAGATAGATAGATGATAGACAGATTGATAGATGATAGAGAGATAGAGATAGAGAAAGAGGAGAGAGAAATAGAGAGAGAGAGAGAATGTGTGTGAACCCAAAGTATCTGAGACAGGTCTCAATCGATTTAGAAAGTTGATTTTGCCAAGGTTAAGGACACCCCCGTGACACAGCCTCAGGAGGTCCTGAGGACATGTGCCCAAGGTTGTCAGGGCACAGCTTGCCTTTAGACGTTTTAGGGAGTCATGAGACATCAATCAACATGTGTGAGATGTACATCGGTTTGGTCGGGAAAGTTGGGATAACTCGAAGCAAGGGCTTCCAGGCCATAGGTAGATAAGAGACAAAAGGCTGTATTCTGAGTCCTTGATCAGCTTTTCACTGAACACACAATTGAGTCTGGCTCAGTTCATCTGCATTTTTACATAAAAAATAGGGCAGAGGAAGCAATCAGATACGCATTTGTCTCAGATGAGCAGAGGGATGATTTTCTGTCCTGCACCTGGGAAGATAAGCTATCCATTTACAATGCCAAGGTGAAAGTCAACAGAACTGTTTTAGGGTAAAGATCTTTAGGCCTGCAAGGAATGTCCTTGTAGAGAATTAAAAAAAAAAAAAAAAAACTTTGCAGCTATCTTATTGAGGAATAAATGAGAGGCAGGTTTGCCTGACGTAGTTCCCGGCTTGACATTTCCCTTGGCTCATGACGTTGGGGTCCTGAGATTTATTTTCCTTTCACACTAGATAGATAGACATTTATGTTAAGGAACTGGCTGACAGGATCGTGGGGGCTGGCAAGTCCGAAACATCTTGGTAAGCCAGGCTGGAAGTGCAGGCAGAAGCTGAGGCTGCTCTCTTAAGGCAGAATTTCTTATTCAGGAAACCTCATATTTGCTCTTAAGGCCTTTAAGTGATTGGACGAGGCCCAACTACATTATCTAGGACAATTTCCTTTTCTAAAGTCAACTGGCTGTAGATATTAACCACATCTATAAAACACTTTCACAACTCCTAGATGAATGTTTGGTTAACTGACTGGGTGCCACAGCCTGGCCAAGTTGACATATAAGACTATTCCAGTCCACACCTTGTCAATTTGGCACCCATGTGCATCTCCTTAAACCATCCTTCACCTCCAAGTAAACACAGGAACAAAATCATACTCCTGCCTAACATGATAGAACTACCAGTGTACAACCAAAAACGCACTCCCGGCTGGGCGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAAGCCAAGGCAGGTGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGCAGGCACCTGTAATCCCAGCTACTCGGGAAGCTGAGGCTGAAGAATTGCCCAAATCCAGGAAACGGAGGTTGCAGTGAGAGGAGATGCGCCGCTGCACTCCAGCCTGGGATAAACAGCGAGACTCTGTCAAAAAAAAAAGCACCCCCCATTCCTCCAGAAAAGGATACCAAAGTCCTTGGGTCCTAAAGGAGAGGCTTCACCTTTGACCTACCCTGGCCCTTCCCTTGGCTGATTTTTCAG
Seq C2 exon
AAACCCAGATCGAGACTCAAAGCCCTGGTGCTACGTCTTTAAGGCGGGGAAGTACAGCTCAGAGTTCTGCAGCACCCCTGCCTGCTCTGAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000104368-PLAT:NM_033011:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0005113=Kringle=PU(64.6=89.8)
A:
NA
C2:
PF0005113=Kringle=PD(34.1=87.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)