HsaINT0134072 @ hg38
Intron Retention
Gene
ENSG00000073756 | PTGS2
Description
prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605]
Coordinates
chr1:186678261-186679201:-
Coord C1 exon
chr1:186679058-186679201
Coord A exon
chr1:186678405-186679057
Coord C2 exon
chr1:186678261-186678404
Length
653 bp
Sequences
Splice sites
5' ss Seq
CATGTAAGT
5' ss Score
8.31
3' ss Seq
TTTTTCTTTGAAAATTTCAGCCA
3' ss Score
5.71
Exon sequences
Seq C1 exon
CGGAATTTTTGACAAGAATAAAATTATTTCTGAAACCCACTCCAAACACAGTGCACTACATACTTACCCACTTCAAGGGATTTTGGAACGTTGTGAATAACATTCCCTTCCTTCGAAATGCAATTATGAGTTATGTGTTGACAT
Seq A exon
GTAAGTACAAGTGTCTTTCTAAGGTTTTTAGCCTTCTCAAAGAAAAATATGCTTTATAATACTGTAAGCCTAATCTAAAAACATATTTCCAAGCTTATCAAAAAGACTTTAAGATAGCTTTTAAGTTTGCCTTCCATCTTAATCGCCAAAAATATTGACATTTAGTCCCATCCAGTTTATACAGTCTGCTCACAACTCTGTATACCTCTTCTAACCTTTACTGTTTGGTCAGTTTGTGGAGGTAGCATGGTCCAGCTGTTTATTGAATGCCCATGGGCCACAGAATTGTTCTGAACATGTAGCACCCATTAAAATAAATTTGGATTTGGATCAGCAAGAAAATAACTTTCCATGATTCTAAAGTGGGTGCCATACTCAGCCATTCCTTTCATAGGCCTCTTGGATAGTGAGCAGATGGCTACCTGAAAAATCAATATTGCCAGATTATAATGTGCAGAGTATATGTATTTTATTAAAGATGTATTTCAAGTGGCCATTAGACTATAAAGTGTAGTTGTTTAAAAATAGATTTTTTTTATTTTGGAGTTACATTCAACCTCAGGTGCCACTTTCCACATTTTACAATAAAAATAATGGTTGATTTACTTAACAAATGAGAATAAATAAAACATTTTTTTCTTTGAAAATTTCAG
Seq C2 exon
CCAGATCACATTTGATTGACAGTCCACCAACTTACAATGCTGACTATGGCTACAAAAGCTGGGAAGCCTTCTCTAACCTCTCCTATTATACTAGAGCCCTTCCTCCTGTGCCTGATGATTGCCCGACTCCCTTGGGTGTCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000073756:ENST00000367468:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.061
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0309810=An_peroxidase=PU(6.1=55.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATTATTTCTGAAACCCACTCCAAACA
R:
GACACCCAAGGGAGTCGGG
Band lengths:
262-915
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development