HsaINT0134073 @ hg19
Intron Retention
Gene
ENSG00000073756 | PTGS2
Description
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) [Source:HGNC Symbol;Acc:9605]
Coordinates
chr1:186646781-186647536:-
Coord C1 exon
chr1:186647393-186647536
Coord A exon
chr1:186646963-186647392
Coord C2 exon
chr1:186646781-186646962
Length
430 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGT
5' ss Score
10.47
3' ss Seq
TTAGCTTTCTCATTTTTCAGGTA
3' ss Score
11.11
Exon sequences
Seq C1 exon
CCAGATCACATTTGATTGACAGTCCACCAACTTACAATGCTGACTATGGCTACAAAAGCTGGGAAGCCTTCTCTAACCTCTCCTATTATACTAGAGCCCTTCCTCCTGTGCCTGATGATTGCCCGACTCCCTTGGGTGTCAAAG
Seq A exon
GTGAGTAAGAAGAATCCATTAGAGATGTATTAACTATAAGACGGGCTGCATTGCTGCCAAAAAAAAAAATTGACCTTAGACTACCATTTATTTATTAACAAAAGCAGTTTTTACTTTTAGCATGGTTATCTATGGGTATTTTTTAAAGTATGAGTCTATATAAACTATTATGTAAAAGCAAATGAGCGTCTTGGTATAATGTCTTAATATTTTCAAATTATTTCTTTAGAAATGAAATAATTCTAATTAAAATAGATAAAATCATTCAGTAAGAAGTTGTTCCACCATATCTTAGAACTGTTGTTTATATTATGATCCTATTCACAATTGTAATTCTCATATAAATGAAGAATTCTTGGTAGATTGACAGTCACCATCTCCTTTCTTGAATACATAGATGGATTCTTACCTTAGCTTTCTCATTTTTCAG
Seq C2 exon
GTAAAAAGCAGCTTCCTGATTCAAATGAGATTGTGGAAAAATTGCTTCTAAGAAGAAAGTTCATCCCTGATCCCCAGGGCTCAAACATGATGTTTGCATTCTTTGCCCAGCACTTCACGCATCAGTTTTTCAAGACAGATCATAAGCGAGGGCCAGCTTTCACCAACGGGCTGGGCCATGGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000073756-PTGS2:NM_000963:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.061 A=NA C2=0.049
Domain overlap (PFAM):
C1:
PF0309810=An_peroxidase=PU(6.1=55.1)
A:
NA
C2:
PF0309810=An_peroxidase=FE(13.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAGATCACATTTGATTGACAGTCC
R:
CCCAGCCCGTTGGTGAAAG
Band lengths:
319-749
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)