HsaINT0134074 @ hg38
Intron Retention
Gene
ENSG00000073756 | PTGS2
Description
prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605]
Coordinates
chr1:186676833-186677830:-
Coord C1 exon
chr1:186677649-186677830
Coord A exon
chr1:186676917-186677648
Coord C2 exon
chr1:186676833-186676916
Length
732 bp
Sequences
Splice sites
5' ss Seq
GGGGTAAGA
5' ss Score
7.83
3' ss Seq
ATTTTTTCATCATTTTCTAGGTG
3' ss Score
11.54
Exon sequences
Seq C1 exon
GTAAAAAGCAGCTTCCTGATTCAAATGAGATTGTGGAAAAATTGCTTCTAAGAAGAAAGTTCATCCCTGATCCCCAGGGCTCAAACATGATGTTTGCATTCTTTGCCCAGCACTTCACGCATCAGTTTTTCAAGACAGATCATAAGCGAGGGCCAGCTTTCACCAACGGGCTGGGCCATGGG
Seq A exon
GTAAGATAGAGTTAATATCTTAGAGTTAGTAAAATTATACCAAATCATAGTCAAGGGCTAACATTAAAGGAGATATACAGATAGATAGATCCAAATAACTTATCCACTTTTTTTAAAAAGAAGTCTTATCTATAAAAACCTTAAAGGAATTTTCCATTTACTTCACTGGTCTAGTAAAATTATACACACACACAGACATGCACACACATATATAAACATTCACACACATACATATGTACAGGTATTGTTATTTGTAATTTGACCCTTGTATTTTTTAGTTTAAAATGTTAGTACTGCAAAATGTTATGTCCTCAAAAACACATTGTACCATGATTATGCCGCTTTCAATATTGTAAAGTGAGGTTTTTGCCGCATTATTATTTTTTGGATTTCAATAGCATAGCTTCAAGTTATTCGTAAGAATTTTTTATAAATAATACATTTTTATACTTTTTTATAATTACCATATCATCATAGTGAAGTATATAATATATATGATATAAGCTCAATATAGTATATTAATTCCGTTAAACACAAAGACATATCAGTTTGTAGCTTTGGTGGATAAACAAATTAATTTAGCAATTCATGGCTATGAAAAATGTATATTTTATTTAAAAATTTTAAAGAAAGCTAAATGATCAAATTATTTAATGATGAATTATATGATAGACACTTTATATAAGAAAAACTTCAACAGCAACAAATTAAAATTTTTTCATCATTTTCTAG
Seq C2 exon
GTGGACTTAAATCATATTTACGGTGAAACTCTGGCTAGACAGCGTAAACTGCGCCTTTTCAAGGATGGAAAAATGAAATATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000073756:ENST00000367468:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.046 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0309810=An_peroxidase=FE(13.5=100)
A:
NA
C2:
PF0309810=An_peroxidase=FE(6.1=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTAAAAAGCAGCTTCCTGATTCA
R:
CCTTGAAAAGGCGCAGTTTACG
Band lengths:
246-978
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development