HsaINT0137364 @ hg19
Intron Retention
Gene
ENSG00000079337 | RAPGEF3
Description
Rap guanine nucleotide exchange factor (GEF) 3 [Source:HGNC Symbol;Acc:16629]
Coordinates
chr12:48137770-48140682:-
Coord C1 exon
chr12:48140643-48140682
Coord A exon
chr12:48137852-48140642
Coord C2 exon
chr12:48137770-48137851
Length
2791 bp
Sequences
Splice sites
5' ss Seq
AAGGTGTCT
5' ss Score
2.57
3' ss Seq
CTCGTTCCTCTTCCTCCCAGGCC
3' ss Score
9.98
Exon sequences
Seq C1 exon
GTTGGAGAATGGCTGTGGGAATGCATCTCCTCAGATGAAG
Seq A exon
GTGTCTGCCTGGCCCCAGTTTCTTTCCTCTGCTCCTCCTGGACTGCAGGCCCCTCCTTCGCCCCCTGACCCTGAGGGGCTCTGTGGGCGTGGGAAGCTCTCCTCCCACAGACACACCCTTGGGTCTCTGATAGGTGTTCACGGGGCCCTTGCTGCATGTGGTGCCCTGGGCCAGGCCGTGCCAGGAGGCGCAGAGGCCTAAGGTGGCCTCCCTCCTCGCCCACTCCCTGACTCAATGGGCCTTTTATTCCTTTTGGGAGGTAATTCATGCCCACAGGTAGAGCCTGGGAGATGAGGAATGGTGGCTGGAGTTGGCCCCTGAGGCCCACGGGGCTCCTGGTGGCCAGTGCTGTGGGAGCTCAGAGGAAGGCGAGGCCCCTCCCTGGAAAGTCAGAGGGGGCCCCAGGCCATTCTCAGCTGGGGCTTAAAGGGAAGCAAAGAGGGGATGAGAAGATGTGACTGCAGCCAGGATTTGGTTGAGGAATGGTGGGAGAAAGAACTGGAAAGGTAGATTAGGTTGGTGGTGGGGAGGGCTGCACTGGGAATAAAATCCAGGGGCCTCACCATCCAGCAGGCTCCCCATGGTCCCACCCTACTGTGTGTCCCAGCCCCTGCCTGCTGGAGACTCTTACTGGCTTCTTCTCCTCCGCAGGCGAAGCCCGTTCTCCCCTCAGGGCCTTTGCACTTATCCCTTAGCCTGGAAGGGTCTTTCTCTGGCTCTGCCTGGCAGGATCCTTCTCGTTCTCATCTCAGCCAAATGCTGGGTTCCCAGACAGGCCCCCTCCCGTCTCCCTATCCGGAGCACCCTCCCCTTTCTCCCACCACGCTCTGCCTTGGTGTCCTCTGTGATTTTCTTCAAAGCACTCTCGCCATGTGGAGTTGTTTTCTTTGCCTACTTGCTTTCTGTCCTTTGGTATCTCTCCCATCCCACTGGAGAGTTGACTTCCCTCCTGCGGGCCCCCACCTCCGCTTCTCCTTGCTCACATGCTGCCTGGCTCTTGGCTGACGCTCAGAAACTGATGTGGGCTCACCCTCGCAGGCCGGGCACTGCGCTAGGTGCTGATGCTGCACCTCATTCAACCCTGGCCTGTGGGGCTGCAGTCAGGCAAGGGGCAGAGCAGTTCAACAACCCGTGATGTGCAGTGACACGGGACACTTTCCCTGAATGTGCACTGGAGTCGGCTCTTCCAACTGTAGTCCGCTCCTGAAAACGGGAGGGGAAGAGCCAACTCCAGTGCAGATTCAGGGAAAGTGTCCCGTGTAAGCGACTACTGGAGTTGAGAGCTGCAGGGGGCAAGGGTGGAGGAAGAAGAGGATTCCTGGTGGGCAAACCCAGGAGGAAAGGGAACCCAGGAGGAGGATCCCTGGAGGAGCGAGAGTAAGAGTAGGACCCCAGAGCAGGCAGGAGGTGGGCAGGGCCCCCTGGGCCAAGGACAGGGGTCTGATCTTTGTCCTAAGAGCAGTGCAAACCATTAAAGGGGTTTGAGCCAAGGTTGGCAAAGTCTGATTTGTGTTTTGAATAGGTCAGCTAAAGAGCCTGGGCTTTCTCCAGCAGACAATGGACGCCACTGAAGTCGAGTGCGGGAGCTTCACAGGGCTCTGGTCAGGCAGATTGGAGGAGGAGGGCTGGAGGCACCTGGGAGGGAGGAGGAGGAGCATAGTTGGGCCATTGGAGTAGATAAGGAGTGAGGCCTCGTGGGCAGGTGGAACTGGAGTTAGCCTGGGCAGGGGAGGAGGGGGCACAGAAGACCCACTTCAAAGAAGAATCTTCAAAGCAAGATGACAAGCTACGGAAGTGTGGAGGAGCCTGGAGCTGGGGAGAATGGCTGGGGAACAGAGTGGTCTGGGAGGCAGGATGCAAGGATCCGATGGGTATATGGAGTGTGAGGTAATGGATCATTCATGTGGAAGGATGCAGGGGGTTTTTGAGACCAGGGTTTGGAAGAGAGTTCAGCACTGCTGGTAGTTTTGGGAATCACCCATGTGCAGGCGACACATGAGGCAGTAAGGAACTCTGCAGGGGTCCCTGAGATTTGGAAATGTAGGGAAGAGCAATGGATTGAGGTCCGAACCTGGAGGATCTGCTATACGCAGAGCTGGGAGGAGGGACAGAGTCAGTACCAGAGTCGGAAAAAAGCAGGGTGGGAAGGGGAACCTGAGTCAGGAGACTTGCCTGGCAGGCGCTGCCCTGCCAGCAGAGGCCTGACAGTGGTTTCCATGAACTGCATCCCTGCTGTGGGCTGGGACAGGGCCACTGACACAGTATCGGAGCACAGAGGGGGAAAGGAGCAGGAGGGATTCCAACTCTGCCAGTTAGCAGCTGTGTGGCTTTGGGCATGTTACTTAACCTCTCTGAGCCTCATTTATTTCATCCATAAAATGGAAATAAAAATAATACTTTTGTCAAAGGCGCATTGTGAATATTTAGATCCTCAGAATAATGCCTGGCTTGTAGCAAATGGTAGCTGGAGGAAAAGGAAGAGAAAACCAAAGTCAGCAGCTGAAGGATTTTCATATTAGAACTGCTCTGGACCTATCTGGCAGATGCAGAAGCACACACACACGGAGGGGCATGGATTTGCCCCGCCCTTAGACATGTTGTGTCTTCTCCTGGATCCTTGGTCCCAGGTGCCTTACCTGAGCTCAGGTGAATGTGGCAAGCAGAGCCCTCTGGTGGTGTGAATGCTGTGTGGCGCCCGTGCTCCTGGTGACACAGGGACCTCACAATCCCTCCCTCCACGGTCTCCTCTCATGTCCTCCCAGCCTTATTTTCTCGTTCCTCTTCCTCCCAG
Seq C2 exon
GCCCGGAACTTGCCTGTTTGGCTCCCCAACCAGGACGAGCCCCTTCCTGGCAGCAGCTGTGCCATCCAAGTTGGGGATAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000079337-RAPGEF3:NM_001098531:16
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.281 A=NA C2=0.250
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)