HsaINT0137432 @ hg19
Intron Retention
Gene
ENSG00000136237 | RAPGEF5
Description
Rap guanine nucleotide exchange factor (GEF) 5 [Source:HGNC Symbol;Acc:16862]
Coordinates
chr7:22165222-22170719:-
Coord C1 exon
chr7:22170655-22170719
Coord A exon
chr7:22165277-22170654
Coord C2 exon
chr7:22165222-22165276
Length
5378 bp
Sequences
Splice sites
5' ss Seq
CTGGTACGT
5' ss Score
9.57
3' ss Seq
TTTCCTGTTCTACTTTACAGCAT
3' ss Score
9.88
Exon sequences
Seq C1 exon
ATGTAACATTTATTCATGAAGGAAATAAAACTTTTTTGGATAATCTTGTCAATTTTGAAAAGCTG
Seq A exon
GTACGTAAATTTCATTACTTCTCCCTTTTTTACAGTAACAGAAATGTATGCCTTTCTTTCCTGCTCTAGGAAATAAATAGTTTTAGTACTTTTCTCCATTGGATGCATGGCGAATTCAAGGAGCTTATTTGCTTCATTCAAGGAGCTTATTTGCTGCATGTTGTACGCTGCCAACAAAATGTATTCCAATTAACAACAAGTATGTTAGCAAGGTTTTTGTGAACCAAATATGAAAATCTGCGTTTTGTTTTTAAAAATGGAATATGATAAGATGAAGAACTGAGGGTATATTATTGAACCAGAGCTAAAACTGTAAGGCTGCTGTCAGGAGGAATCCACACTCAGGAGATTATGTTTTACTGCTTTATAGGCATCTCTCAGTGTCTCAGCCTGCATGCTTTCAAGGCACAGAGGGAAAAAGTTCCTCTCCTGGGGATATATGTTTGTCTCTCAGGACTCCAAGCTTAAATGTGAGGCTGGAATTTGCAGGGTCTTGTGTGAAGGGAAGGGCCACTCCTTTATCAGCCTATGGACAAAGGGTGCCATCCCTGAGCACCACGGCCAGAGCGGCTCAGGCAAAGTACCCTCCCTCCTTACAAGCAAGAGGTTCCCAGGGCAATCCTCTCTAAATGTTTCTGAACCACTGCTTCCTGAATGATTTCCAGGGCATTCCCAGGTGCTTTGTAATACAGTGGGCCCCTCCAAGCCTTTCTGACTTGCCCTTGAGCAAAGGAGGGGTTACCCATAAGAACTGAGCAACTGTAAAATAGAAGTACTCCAAAGAGACCCACTTGCCTGCAAGAGGAATGGATTTATCTGACAGATGAACTTTAGTGTCATAGAGTAAACTGTCCTTCATGGTTAAAGACGATACCAGTAACCCTGCTCCACAGATCCTGACCTTTGAGTGACCTTTTCAGTAATGGTGATGGATTTGTGTGAACTCTTGCAGAAACTGACCCTGGTTCCCTGTGAGACTGAGTCAGGCACTTGAGAGGAGGTTAAGTGAGGCAGGGACCACAGACCATGATCAAAGAACGGTAGGAACTGATGAGTCCTGCTGAGGCTTGGCACCTGACCTTTGCCTCAGAAGTACATTGCTCTGCTTACCCAGCCAACTCCCCACATGTAGGGTGAAGCAGCTTGGGAACAGTGTAGTTGGCTCTTATACAACCCTTATACAACCCCCAAAACCCAAGCATCTGGAATATAGAATACAGTCTTGGAATATCTTGCTTTATCTCCATTTTAACCACACCGAAGACCATCACTTCACGGCTAGTGCTTTTCTAAGTGGCTCTGTCAATACATTTTCAAGTTTGTCTCTGCAGTAAGTGTTTTGGAATCAGAGCTCAGTTATTTTAGATGCTACAGTCAAACCAACAGAGCCAGAAATGGATAAAGTGTTATTTTTTTGTACGTGTTTTGTGTTGCTGTGTGATATTCTGAAGATCACAGGGCACTTAATGAAAGGCTGCAGGCACTAGAATTCTTGCCTCTAAGCAGGTTAATCCCTGTCGTTTGGGATTAATGAAACAATTGCGGGAATATGAAGCCTTTGGTCAATATTTACTTCGCTTCCTGGCCAACACATCTCCCTAAGAACAACACATGAGATTTGTGGAGCATCTGTGAAGATGTGGGATGAGGTGTGTCACGCCAAGTGGAATTCCCTGGAAAGGCCTAGTAATCCTTTCCCCTGACTAGTCCAAGGGGCCGTGGGAGAACAACTAAACTCTTTATCAGCTGGCTGTTGCCTGTTGTTGAGGGCAGACGTGAGGTTGACCTCCCTAAAGTGAACCAGTGAATTTGTTAAGTTCATTATGTCATTTCCCCCTCAGATAGTGCCACCAAAGTGACAAGATAATAAAAAAAAAACCTGAACAAGTCCATAAAGTCACAAATGGGAACAAGCTGTGGAAAGCTTGTTCCCACCTTCCTTCTGACCAGCATCTGTGGCCCTCCCCTGCTCTCTCCAGTAATCCAGCAGAAGCCTCTTAACGCCAGCTCTCAAATATGCCAAGACTGCCAACTAACCATAGGGCTGGAAATGAAGGAGGTCTAAATGATATGACTTCTATTAGGGTCAATCATCATACCCTTAATTCTTTGAGAAAGTTTAAGGGAATAGCATGGCATAAATAATATTTTAAATTCCTAAAGAGAAATTATATTTTATAAAAGAATGAAGAAATGGGTGCAGTTCAGCATGCACACAGCACTCACATAGCGCACACGCAAGCCCGTCAGGCAGGCACGGGCTCTTCATTTCCTCAGAGGGCAGGCTCCACACCTGGGACTAGTGAGCTCCTGGTCCACAGCATGCCTCATGCTGACCCCTCCTTACACAGAGTAGACAGGATAAAACTGTGTCCAGGACAAAAAGCAGTTTTATGTCATATATAGCATTGTGTTACACTTGGATGCTGGAGAATGAGACTGACCTTTCTAGGAGAAACACTATTTTCAAGGAATATTTCTTAGTAAAGGACTGGGTTTCTCTAAAGGTAAAACAGGATCATCTTTCACGATAATGAACCAATAGAACCTAAGTGAATTAACTTGTGAAAAGTCAATTCCTCATGATGGATATTAACTTAAGCCAGCTAACAGATAATTCAGTGTATTATCTTTATCTGACTGATGCAGGCCAGTACACTGAGTCAGACCCCATGAAAATCCAGAAGCCCTCATCAGGTCTAATGAGATTTCTGTTCTTTATGCTACATTCCTTGCTGCCTCAGCTACTGGAAATGTTTTCATCTCAAACTGTTTCATAAAAAGAAACAAATGGTTTCTTTTCTTCTCTTTATCCCTCGATGTTAAGAGCATCATCTTTTACCCTGTCTACCCCCTCCCCCTTTAGAAAGCCTAAAGATGAAGACCAGAACTCAGGTTTCAATGCCACACCCACTACCCAGCCTTACATCAGTTTGAGCCTTGCACAAGCTACGCAAATGGCATATGATAGAAATCAATGTGACGCCAGAGCTTAAAATGAGAAAACTGACCTGGGAAAAGTGGTAAAATCTGGGGAAGGAAACTGAACAATACATGCACAGACATGAGTCAGGTCTCATTTCCTTTACAAATGCAGCTTGAGCTACTGCAATAATCACTGTCCTATTCAATTTTCCACTATCGAATAGAAGTGCATTAGAAATACGGTTATGACAACAATTCAATCAGTAGGTCATATTCCAATAATATTTCTGTATTTCTTCTGAATTTTAAGTAAGAACATATTTTAGTGTTTAATATTCTTTCAGCAATAATTCATTGAGGGTTTGCTGTATATGGTGATCCTATGCTCAGTGTGTATAGTTGGGACATGAAAGATGTTGACCCAAATTGGAGGCCCAGATATGAATGATATTAATTCTTGAATAATAGGATGATGTTTGTATTGTGATATGAAACAAAGTAGAGAGCTACTGTTGATTCTCAAGAGAACTAGAACATGAAGACAATAGTATTTAGAGATTATTCTGGCAATTAAGCCAGCTAGCATAGCATTTTGGAAGAGAACATACTGCACTCTAGTTCCTCTTATGGCATATACGTATATGCTTCCAAAATGCTACTTCCTTCAACATGAAAAACTAAAAGTGGTAGAGACAGCTCACTCTTGCAAGTACAAAAGTATAAGATGATGGGATCTTGTCCAAAGCAGCTGTACATTTAAGAAGACTTTTGCCGGCCAGGTGGGGTGGCTGATGCCTGTAATCCCAGCCCTTTGGGAGGCCAAGGTGGGTGGATCCTGAGGTCAGGAGTTCAAGACCAGCCTGACTTGAACATGGTGAAACCCTGTCTTTACTAAAAATATAAAAATTAGCTGGGTGTGGTGGCATGCCTCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGGAGTAGAGGGTGCAGTGAGCCGAGATCACGCCATTGCACTTCAGCCTGGGTGACAGAGTAAGACTCCATCTCAAAAAAAAAAAAAAAAGAAGACTTTTGCCTGGGAATCAGTGAGGACTTCAAGGAAAGAAATTAAATTAGAATATTGAAGACTGTACGTGAATATAAACTATGAACAGAAAATGGTCTCTAAAGATGTTGATGTTGGCCGGCCACAGTGGCTCACACCTATAATCTCAGCATTCTGGGAGGCCAATTTGGTTGGATTATCTGAGGTCAGGAGTTCGAGACCAGCCTAGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAAAATTAGCCAGGTATGATGCATATGCCAGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAACTGGTGAGGCAGAGGTTGCAGTGAGCCAAGATCACACCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCCGTCTCAAAAAACAAAAAAAATGATGTTAATGTTTTAGAAAATGTTCATCTTTTGTCAGTATCTCATTTCCAGTTACAATTTAAGATACTTGAACCTTTGAATCTACAAGAATTCCTACCTCCATTCAGCACATATGTGTAAGTCAATGTGTCTGACATAGTAGGCTCTGCACATCCAAAGCCCTCTGGTGGTACTTGGTCTAAAGAAGGAGAAAAGTTCAACAGCAATGACAGTGACACAAAGCCAATAGGTGCTGTACGAAGAGCAGTGGGGATGTTGAGATTGGAGCCTCTGAGTCCAGGAGGGACATCTCAGAAAGGCTTCATGGAGAGGAGGTGACACATACCCTGAAGTGAAACACATGTGCAAATGTGAACAGGATGACTGGGGCTGGGGGTGCTGCACTTCTCTACAATGTATTTTCTCATGGCTCATAAGAACCTGTGCAACCCGGATTGGGTGCTACTGTTTTTTGTTTGTTTGTTTTTGAGACGGAGTCTCACTCTGTCACCCAGGCTGGAGTGTAGTGATGGGATCTTGGCTCACTGCACCTCCGCCTCCCAGGTTCAAGCGATTCTCCTGTCTCAGCCTCCCGAGTAGCTGGGATTACAAGCACCTGCTACAACCCCCAGCTAATTTTTTTGTATTTTTAGTAGAGATGGGGTTTCGCCATATTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCGCCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGAGAGCCACCTCACCCATTCTGGTGCTACTGTTTTTGCAGATAAGGACTAAATATTCTTTGATAATCCAAGCTCCATAGAATCAAAGCTACATCCAGCTCCAAATACAGTTCTTCTCTTTATTACAGCCAAGAGTGCTAGATTATCCTTCCATCCTAGCAGGCACTGCTTCTTCAGTAACACCCTCAACGACCCTTCCATTGATGTGTTTCCTGTTCTACTTTACAG
Seq C2 exon
CATATGATCGCAGACACTGTCCGAACCCTGAGACACTGCAGGACTAACCAGTTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136237-RAPGEF5:NM_012294:24
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.053
Domain overlap (PFAM):
C1:
PF0061714=RasGEF=FE(11.4=100)
A:
NA
C2:
PF0061714=RasGEF=PD(0.5=5.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)