HsaINT0137473 @ hg38
Intron Retention
Gene
ENSG00000108352 | RAPGEFL1
Description
Rap guanine nucleotide exchange factor like 1 [Source:HGNC Symbol;Acc:HGNC:17428]
Coordinates
chr17:40177495-40181694:+
Coord C1 exon
chr17:40177495-40178381
Coord A exon
chr17:40178382-40181615
Coord C2 exon
chr17:40181616-40181694
Length
3234 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGG
5' ss Score
11.08
3' ss Seq
GTGCCCACTGATCTTTACAGATA
3' ss Score
7.08
Exon sequences
Seq C1 exon
CGCAGCCGCCGCCGCCGCCGCCGCCGCGTCCTCTCAGCCTTGCGCTCCGCCCGCTGCCTCTGCCGCCGCAGCGCAGAGCCGGGCGCACCGGCCCCGCAGCCTGCCCACTCTTCGGGCCGCGTGCCGGCTGCAGCCGGCATGGGGGGTTGCTGAGAGCGAGCACTCCTTTCCTCTGGCACCTCCCCCGGCTACTGGCCACTGGACTCTGGCCAGCGAGGCTCGGCCCCTCTGGCCCCCAGTCTGGCGCCTGGCACGGCCCTCTACTCTGCTCCTCCAGCTCTGAGCATCGTGTCTTCGCCGCCCCCCCCGCCCGCGCCTGGGATACCTGGGTCCCCCGGCGACCCCTAGGAGAGGGGCGGGGGGGGGCATGAAGCCGCTGGAGAAATTTCTGAAGAAGCAGACGTCGCAGCTGGCGGGCCGAACGGTGGCGGGAGGTCCCGGCGGGGGTCTGGGGAGCTGCGGTGGGCCTGGAGGGGGTGGGGGACCCGGCGGGGGCGGCGGTCCAGCCGGGGGACAGCGGTCGTTGCAGCGGCGTCAGAGCGTGTCTCGCCTGCTGCTCCCCGCTTTCCTCCGGGAGCCCCCCGCCGAGCCGGGGCTGGAGCCGCCCCCTGAGGAGGAAGGAGGAGAGCCGGCGGGGGTCGCGGAGGAGCCGGGCAGCGGGGGGCCCTGCTGGCTGCAGCTGGAGGAGGTGCCGGGGCCCGGGCCTCTCGGGGGAGGGGGGCCCCTGCGCTCCCCTTCCTCCTACTCATCTGACGAGCTGTCCCCAGGCGAGCCCTTGACTTCGCCGCCCTGGGCCCCTCTGGGCGCCCCCGAGCGGCCCGAGCATCTTCTGAACCGGGTTCTGGAGCGGCTTGCTGGAGGGGCTACCAGGGACAGCGCCGCCTCAG
Seq A exon
GTAAGGAGCCGGTGGGCTCGAACACCCAGAGCAGGGGCTGGCCCCGGCTCCTCTTCCTTGCCCTTGGAGCGTAGGGGTGGCGCCGTGCCGGGGCTTGGTTATAGGGTTGAGTGGTCCGCGGAAGCCGGCTAGGGGCCTAGCGGAGGTACAGACCCTCCCGCGGAAGAGGAGAGCAGTACTCACCTTCCTCCCTACAGCAGCCTCACCCTCGTCTGGAGAAGCAGCTGAGCCTCTTACTCTCCTTCAGCCACCCTTCCTTTCCCCTGGGCATTGGAGCCACTGACTCCCATGGGTCCCTGATGTTGAATACCTCCTCCTGTGGCCCCAAATTAGGGCCTGACACATTAAAATGGGAGCTGCCCAGCGCAGCCATGCCACCCGCCAGAGGTGCTTTAGCCCTGAAAACCCTGGGGTCCCTGACTGTTCAGAGGCCTACACAGCGCAGGCTGACCCACCCAGGGAGGCAGTGCCAGACAGGCACAGGCCCCAAGCTGCCTTTTAGGCATCAGCAAAGGGATGCGTTGTCCTTAGCAGTTTGGTGGGGGGGATAGTATTCTCCTTGGGCTGGACTCAGAAGGTGTCTGGGAGGGGAGAGGTGGCTGGGCCGGCATCATGGCCCTGCAGCATCCAGGGTGTCCAAGCGCCTCCAGCTTCCACCCTTCGGTGGCAGGCCTCAGCACCCGGCTTTTTTTTTTTTTTCTTTTGGAGATGTAGTCTCACTGTCACCCAGGCTGGAGTGCAGTGGCGCCATCTCAGCTCACTGCAACCTCCACCGCCCAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCATGTGGCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGACAGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGAACTCCTGACCTCGTGATCCACCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGGCCTGGCTAATTTTTGTAGTTTTAGTAGAGACGGGGTTTCGGGGTTTCACCAACTTGGTCAGGCTGGTCTTGAACTCCTGACCTCGTTATCTACCTCCCCCCACCCCCACCCCACGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGGACCTGGCACACGGCCTCTTTAAAATATAATCACCACACCCTGAGAAGCTTATTCCCTAAATGATGATACTATTTCACCACTCCCTTTCAGCACCCCTACTAAGGGGCCTTTGAGGAAACCAAGGCCCCAAATCTGGTTAGTTCTGAGGTAGAAGACCGAGGGTTCTTTAGGTCTAGCTCTAGGCATTACTCTAAGCCCAGGAGGGTCTGAGGTTTGGGAGCCCCGGCTGAGGCCCTAATGGTGAGGGCTTTCACACTTGCTCTCAGCCCTCGGCAGGGAACCCCAACCTAGATGTGTGGAGGGGGGCTCCACTCTCCTAGATCCTTCTCAAGACCTGGGTCCTCTCCTTTGGAGCAGGCTGTAGTTGCCCTGGGGAGCTGACACCTTTTGGATTTAATTAGAAAAATATCAGACACACACAGCTCTCCTAACCATAACTTCCCGCCTACACCACACACCCTGTGTCTCTATGACACATTCCCTAGGGAGGCTGTACATTGGCCCAGAGCCTGCTTTGGAAAAGACAGATGCCCAACTGTGGCCCCCATATCAGCATCTCCCCAACTCTGCCCCATCTTACTCTTCCTTTGCTCCAGCTTAGGAATCCTGTGAGATAAAGTCTATGAAGGATGTCAGGCCTCTCGTTTCCTCACCCTCATCCCTGAAGCTGGGGGTCAGAGCTGGAGGCTCTCTGACTCATTGTAAGAACACAGCAGGGTAGCTGGGCAGGGAGGAAAAGGGAGAAGCTGTCTTTCCCCTTTTACAGGGGCCTGGTGCCACACGCTCCGCTCATTCTCCCCTGGGGTAAGACTCCTGAAATGTCACCCATGTTATCTGGCAGCCTGGATCCCCAGAGTAACTAGTTTGGGAAATTCCAAACCAGTCCCAGGTGAATGAGAATCAGCTTAACCTGCCACTCTGATGTTCTCCAATAAAACCAATGTTCTCAAGTCATCCTGGTCTCCTCCCAGGGTGTGTGGGAGGAGAGAACTTACAGAAGTTACTCTGAACCTACCAAAGCCTCTCCAACGTCCAAGCAGCCCCCTCTGACCGCTAGGTTTTACCCTAACACTCTGCTTGCCTCAGGCATATTGAGAAAAGGACAAAGACTCAGGATTCTGGGTTCTTATTCCAGCTCCAGGCAAGTCCCTCCCAGCTCTGGGCCTCAGTTTCACATTTGCGAAATGAAATCCTTGAAGTCAATTACTTTGTGTTGGTTTTCCTCCTCCGCCTGCATGGCTAGAACTGACCACAGGAGATAGTGAACCAAGGGGAGTCAGAAGCCTTGGTTTTGTCCTGGGACAGTGCCTGGGGACCTGGCCCTAACCAGTCCTGGTGAGGACACCTGGCTCCCTCCCTGCACCTTGTCTGTCTGTGTGTGCCAGGTGGCCCTGCCCCACCCCAGGGCTGGCTGCAAGTCAGGGCGACCTTGTACCCGGCTGACTGGCTGAGCCAGGCCCAGACGGGGGTGTGGAGGGGAAAGGGGTGGTGAGAGGAGCCGCTCCCCTTCACCATTCCATCATTAACCCTTCTGTCTCTGGGCCCCTAAAGGACACAGGATTTCTATTTAAAGGTTCTGGGATCAAAGTGATGGCAGTCTCTCCATCTCCCTTTTAATCAGGCTGGTTCCCACCTGCCTAGTTAGAACTCAAAGCTGTTAGGTGGGAAATGGGGAGGGGAAGAGGGATACACACACATGCACACACACAGTCCCCACTGATGCTAACCTCTGTGTTTGGAAATACTCTTTGTCTGGAGACACTTCTGTGGGCTACTTCTTTTTTCAGGCAGAACTCAACCTTGGTGTGTTATCTGACCAACTTCCCACATACGCTGAAGAGAAGTGCACATGGCCATCAAAGGCACGCGCCCCCCCCTTCCCTTCAGCTGCCTTGGCAGCTGCCGAACCCACCCTCGCAGTGGCTGCCCAGAACCTTTACACATGTATGTGTGCGCGTGTGCAGAGCATGACAAGGCAGGTGGCTGGGGCTCCAGCCTGGCTAAAGAGAACTTGCCCTTAGGGGCAAGAGAGGGAGGCACTGCATTTCCAGTTTCGTTCTGGAAGTGCCCACCTGACATCTGTGGTGCCCACTGATCTTTACAG
Seq C2 exon
ATATCCTGCTGGATGACATTGTCCTTACCCATTCTCTCTTCCTCCCGACGGAGAAATTTCTGCAGGAGCTACACCAGTA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000108352:ENST00000613811:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.922 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development