HsaINT0147337 @ hg38
Intron Retention
Gene
ENSG00000185033 | SEMA4B
Description
semaphorin 4B [Source:HGNC Symbol;Acc:HGNC:10730]
Coordinates
chr15:90225661-90227642:+
Coord C1 exon
chr15:90225661-90225827
Coord A exon
chr15:90225828-90227556
Coord C2 exon
chr15:90227557-90227642
Length
1729 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGC
5' ss Score
9.6
3' ss Seq
GAATTCTCTCTGGCCCTCAGGCC
3' ss Score
7.66
Exon sequences
Seq C1 exon
GGGCTGCTGTATGCGGCCTCACACTCGGGCGTAGTCCAGGTGCCCATGGCCAACTGCAGCCTGTACAGGAGCTGTGGGGACTGCCTCCTCGCCCGGGACCCCTACTGTGCTTGGAGCGGCTCCAGCTGCAAGCACGTCAGCCTCTACCAGCCTCAGCTGGCCACCAG
Seq A exon
GTGAGCACTCCCAAAGGCCCCTTCCCATCTGTCCAGCCCTGCACAGGTGACCTCGGAGCACCATCCTGGGCCCTCCTTGGGACCGCCACACAGCCTCGTTTATGTCCACTGTCTCAGCATAATTATTAATTAGCTCTCCTGCTTCCTCTCAAGTGCAATTCAGACAGGAAATTGTGTGTTTATCTTGGCTACCTGTAAAACGAGGACATGATTTGGTAAAGTATGAAATAGCACAGCTTTGAAAAGCCTTGCAGGAAAATGTGGATTAGCGTGTGAACGTGCTTTAGTAATAGTAGGGCTAGGAAACAGTCCATTAACAAACCCAGTAAAAATTGGTTTCAGAATAACCTATTTGGATTATAAAATGTTCATTTAGAAAATAGGGATGAACACAAAGCAAAACTACCCCTCATCCCACCACCTAGAGAGAATCGCAGTGAGATTTTGATATATTATCCTCTCAGGTTTTACTACATATGTGTATAGATAACAAAAATCCTTTTATTTTATTTCATTTCATTTCATTTATCTTGTTTGGAGACTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCACAATCTCGGTTCACTGCAACCTCCACGTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCAGGGATTACAGGTGCCCGCCACCATGCCCAGCTAATTTTTGTATTTATAGTGGAGGCAGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTTCTGACCTCAGATGATCCACCCACCTTGGGCTCCCAGAGTGCCGGGATTACAGCCATGAGCCACCGCGTCTGGCCAAACATTCATATATTTTATATAACATTGGCAACTGTCCTGTTTGTAGTGTTCTTGCTTCACATATGGATACACCTGGTGTCAGTTTTTACAAAAACCAAGTGAGTTTTGGTGCGTATGCCAGGAGGGACACCCCAGAATGTTAACTGTCATGATCACTGGCTGGTAGATGCTGTGATTTTTGTAGTGTTTTCATCCTTCGTGCCTGGTTGACTTATCTGTCTCCTGAGTGTATCCAGAATTACTGTCCTTTATTTTTTATTACACAGATGTATGCATGTGCACTGTTTAAAAAAAAAGATGAGAACACATCAAAAAAAATTTTAATTAAAAAAAAGAAAAAGAGAGATCTATACATACAGATCCCAGCTGTCCTTCTAATCTTTTTCTGAGGGTACATACTATTTTTTATTATTATTTTTTGAGACAGGGTCTCTCTGTGTTGCTCAGGCTGGAGTGTAGTGGTGTGATTACAGCTCACTGCAGCCTTGGCCTCCTGGGCTCAAGCAATCGATCCTCCAACCTCAGCCTCCTGAGCAGGTGGAACCACAGGCGTGCGCCACCATGCCTGGCTAATTTTTCTATTTTTTGTAGAGATGGGGTCTCGCTATGTTGCCCAGGTTGTCTTGAATTCCTGGGCTCAAGCGATCTACCGGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGGGCCACCATGCCTGGCCACTGAGGGTACATACTGTTTATGTAATTAAGGGAAGTGTTATCTTAGCTTTGACTTGAAATAATGTGTAGACAGAGGAGATGCTGACTCCTGTGGGTGGGGAATCAGCTCAGGAAAGGCCCTTGCCCAGGCCCAAGTCTGCAGTGAGGGGTGAGGGAATGTGAGCTCAGGGGACTTCCTGGCCAATCCCAGAATTCTCTCTGGCCCTCAG
Seq C2 exon
GCCGTGGATCCAGGACATCGAGGGAGCCAGCGCCAAGGACCTTTGCAGCGCGTCTTCGGTTGTGTCCCCGTCTTTTGTACCAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185033:ENST00000411539:12
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.021
Domain overlap (PFAM):
C1:
PF0140314=Sema=PD(0.1=0.0),PF0143720=PSI=PU(67.3=66.1)
A:
NA
C2:
PF0143720=PSI=PD(29.1=53.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGCTGTATGCGGCCTCAC
R:
TGGTACAAAAGACGGGGACAC
Band lengths:
246-1975
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development