HsaINT0149189 @ hg38
Intron Retention
Gene
ENSG00000125731 | SH2D3A
Description
SH2 domain containing 3A [Source:HGNC Symbol;Acc:HGNC:16885]
Coordinates
chr19:6754831-6759670:-
Coord C1 exon
chr19:6759594-6759670
Coord A exon
chr19:6755316-6759593
Coord C2 exon
chr19:6754831-6755315
Length
4278 bp
Sequences
Splice sites
5' ss Seq
TGGGTAAGT
5' ss Score
10.24
3' ss Seq
CCCTCTTGTATGACCTCTAGAAG
3' ss Score
6.59
Exon sequences
Seq C1 exon
GGCAAGGAAGTGGAGCAACAGTCAGCCTGCAGATTTGGCACATATGGGGCGGTCAAGAGAAGACCCCGCTGGGATGG
Seq A exon
GTAAGTGTCTGCTAGAATGGCCTGTGGCTCAGGGATTGGCTCTGCCACTCACCACCTAAGAGATCTTGGTCAGGTGCAGGCACCTCTTCGAGCCTCAATTTCTTGCTTTAGAAAATGATGACAATCACGATGACTTAAAACATGCAGGGACTTTGTGGGTGCTTAAAATGTGTGTTTACAAGGCTGAGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCCGGTGGATCACTTGAGGTCAGGAATTCGAGACCAGCCTTGCCAACATGGTGAAACCCCATCTCCACTAAAAACACAAAATTAGCCGAGCGTGGTGGCACGCACCTGTAATCCCAGCTACTCTGGAGGCTGCGGCAGGAGAATCGCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCCGAGATGGCGCTACCGCACTCCAGACTGGGTGACAGAACAAAACTCCATCTCAAAAAAAAAAAAAAGTGTTTACAATTATTCCAAGGAGCTGTACCTGTTCTGACCACAGCTTACCTTGCTAACAACTTCTGCTACGTACCCTCCTCATGCTGGTCACACAGCCCTCCTTGCAGTTGTTCGAACCCTCAGGCTTTTATTCCCGCCTCGGGGCCTTTGCATTTTACATTTCCACCAGTGACGGGAACATTCTCATTCCCCTAATTTTTTCCTGAGTGGCTCCTCTCCATCCAGGGTAAGTTCCTCAAAGCAGTTGAGTCTGACGGTCTTACCTAAAGGAGGACTCACCTGAATGCCCCCTCATGCCCCTTTTTTCCCATCCTTCTCCCAACCCCATTCAACATGAGCCGTCCCTGCATCCCAGGCCCTGCACGGAGTGCTAGGATACATCAACAAACCAGAAAGAGACAAAGATCCCTGCCCGATGGGAGCCAACAGTCCACGAGAGGACAACAAACCATGAACCACAAAAATAAGGCAATTTTGTTTGCTTCAAGATGAAAATTAAAACACAGGAAGGGAAGGCCAGGCACAGTGGCTCAGGCCTGTAATCCCAGCACTTTGGAAGGCCAAGGCGGGCGGATCACCTAAAGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGCGAAACCCCGTCTCTACTAAAACTACAAAAATTAGCCGGGCGTGGTGGTACACACCTGTAATCCCAGCTACTCGGGAGACTCGGGAGGCTGAGGCACGAGAATTGCTTGAACCCGGGAGGCAGAGGTTGCCGTGAGCCAAGATTGCACCACTGCACTCCAGCCTGGACAACAGAGTGAGACTCTGTCTCAAAAAACAAACAAACAAACAAAAAACAGTAAGGGAAGGGTGAGGTGGCTCAGGTCTGTAATCCTAGCACTTTGGGAGGCCAAGGTGGGCGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAAACCCATCTCTACTAAAAAAAAATAAAATAAAATAAAATACAAAAATTAGCCAGGTGTAGTGGCATATGCCTGTAATCCAAGCTACTTGGGACAGAGTGAGACTGTCTCAAAAAAACCGAAAAAACAAAAACAAAACAAAACAAAAAAAACAGAGTAAGGGAGATAGAGACTATAAAGATGGAGATGTATATTGCAATTTTATTTTATTTCTATTTATTTATTTATTTTTGAGATAGAGTTTTGCTCTTGTTGCCCAGGATGGAGTGCAATGGCGTGATACCGGCTCACTGCAACCTCCACCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGTGCACCACGCCCTGCTAATTTTGTATTTTTAGTGGAGATGGGGTTTCCCCATGTTGGTCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCCACCTCAACCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCATTGTACCCAAGCAAGCAATTTTAAGTGGTAGTCAGGAAAGGCCCCATTGCAGAAAAAAATAAAATTGAAGGAAATGAGGGAGGGAACAGGTGGATAACTGGGGGATAAGCAGGCAGGAGGAAGAGGCAGTGCAAAGGCTCTTGGGTCAGAACAAGAATTTAAGCTGTTCATTCAACCAAAAAATGAGTGGGTAGCTGGGTGTGGTGTTGCACGCCTGTGGTCCTAGCCACTTGGGAGGTTGAAGCAGGAGGACTCCTTGAACCCAGAAAGTCAAGGCTGCAGTGAGCCGTGATCGCACCATTGCACTCCAGCCTGGGCCACAGAGTGAGACCCTGACTCAAATTTAAAAAAAAAAAAAAAAAGAAGAAGAAAAGAAAGGGCTGGGTGCAATGGCTCAATTTCTTCTTAAAAAAAAAAAAAAAAAGATACACGTGCAGAATGTGCAGGTTGAGCCTATTCAAAGGCATGGTAAATACAGTCTCCCAAAAGTCTTAGTACAGTTTTAAGTACTAATAGTCCAGAAATTACAAGCCTGTAATCCCAGCACTTTGGGAGGCCAAAGCGGGCGGATCACGAGGTCAAGAGATCAAGACCATCCTGGCCAACATGGTGAAACCCCGTGTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCGCCTGTGGTCCCAGCTACTCGGGAGGCTGAAGCAGGAGAATCACTTGAACCCGGGAGGCAGAGGTTGCAATAAGCCGAGATGGCGCCACTGCACTGTAGCCTGGTGACAGAGTGAGACTCCGTCAAGAAAGAAAAGAAAGGAAGGAAGGAAGGAACGAAGGGAGGGAGGGAAGGAGGGACACACGAGTGTAGCTGAAGCAGAGGGAATGAGGGGAGAGTCAGAGAGAGAGACCCTGGGGCTCAGATTGTGAGGATTTTTCAGCTACTGTGAGCACTTTGGACCTTAACTCAGAGTGAGCCAGGCACTGTTGGATGATTTCAAGTTCCTAGAAAAGAGCCTATTCAAAGGCATGGTAAATACAGTCTCCCAAAAGTCTTAGTACAGTTTTAAGTACTAATAGTCCAGGAGATCAACATGCCACCAACTTACAAAGGACGTCATTTGAAAGTTTACGATGAGGGGAGGGAACTTAGAGGAGGGGTCAGTAGGTGCAGCAAACCACCATGGCACACAGATACTGAACCTGCACATTCTGCACATGTATCTTTTTTTTTAAGAAGAAATAAAAAAGAAAAAAAAGAAAAGAAAGTTTAATAAGCTTGGTTTCTTTGACACTTATCTGAGTGTCATACCATACGCAGCTTTGTGAATTTTTTATACTTTGTCTCTCTATAGATATCTATATTAATTGTATATATTTTATATAGATATGTCTATGGAGAGATATATTATCACAAAAAAAGTAAAATATCTATCATATATAAATGTAATTATATGTAGTATATAGGGCAACATTATACATTTAATAATGTTAATTTTATTTAACATATACTTAATTTAAATATATATTATATATTTATATAATATATATCTATCTCTATAGATATGATATAGAGAGATATATCACTTAATTGTAGATAGATAGATATCTTTTTTTTTTTTTTGAGACAGGGTCTTACTCTGTCATCCAAGCTGGAGTGCAGTGGTGCAGTCATACCTCACTGCAGCCTCTGGCTCAAGTGATCCTCCCACCTCTGCCTCCCAAGTAGCTGGGACCACAGGTGCATGCCACCATGCCCAGCTAATTTTCTAACTTTTTGTAGAAACAAGATCTTGTTATGTTGCCCAGGCTGGTCTGGAATCCCTAGCCTCAAGCAATCCTCTCACCTTGGCCTCCCAAAATGCTGAGATTACAGGCGTCGGCCACCACGCTCATCCTTTTTTTAAAAAAATTTTTAATTTCGTTGGGTCACTGCTTACCATCTTTCAGTCAGAGGGGCAAAAACAAAGAATTCAAATTTAAAATGTAGTATTCAGAATTCATAGGGTCAGGCAAGGTGGCTCATGCCTGTGATCCCAGCAGTTTGGGAGGCCGAGGAGGGAGGATTGCTTGAGACTAGGAATTCCAGACCAGCCTGGGCAACACAGTGAGATCCCATCTCTATAAAATAAAATAAAATTAAAAAAAAATAATTTACAGAACTATAGAGATGCTAAAGTTTTCTAACCATGTGTAAGCATGTAGCATTTCTACCGTCGAGGTGGTTGAAATTCAAAACTGCACCCGGATAGGTTGTTATACCCCATTATTGGAATGAGTGGATGGATCAGGTGGGTGGTAGCCGATGAAGCTCTCACCCCCGCCCATTCAGCAATCTTCCCTGTGTATTCCCATTGACCCCTCTTGTATGACCTCTAG
Seq C2 exon
AAGCCTCCACCATGCCCATATCTGCCTTGCCCCGAACGAGCAGTGACCCGGTGTTGCTGAAGGCCCCTGCTCCCCTGGGAACTGTTGCCGACAGTCTCAGGGCCTCCGATGGGCAGCTTCAAGCCAAGGCACCAACGAAGCCCCCCCGGACACCCTCCTTCGAACTGCCTGATGCCTCTGAACGTCCCCCGACGTACTGCGAGCTGGTGCCCCGAGTGCCCAGTGTCCAGGGAACATCCCCGAGCCAAAGCTGCCCAGAGCCAGAGGCCCCATGGTGGGAGGCCGAGGAGGATGAGGAGGAAGAGAATAGATGTTTTACAAGACCACAGGCTGAGATCTCTTTCTGCCCCCATGATGCCCCCTCCTGCCTGCTGGGCCCCCAGAATCGGCCCCTGGAACCCCAAGTCCTGCATACCCTCCGTGGCCTGTTCCTGGAGCACCATCCTGGGAGCACCGCCCTTCACCTGCTATTGGTAGACTGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125731:ENST00000245908:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=NA C2=0.672
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains