HsaINT0167066 @ hg19
Intron Retention
Gene
ENSG00000156299 | TIAM1
Description
T-cell lymphoma invasion and metastasis 1 [Source:HGNC Symbol;Acc:11805]
Coordinates
chr21:32525384-32526744:-
Coord C1 exon
chr21:32526565-32526744
Coord A exon
chr21:32525453-32526564
Coord C2 exon
chr21:32525384-32525452
Length
1112 bp
Sequences
Splice sites
5' ss Seq
AAGGTATGT
5' ss Score
9.79
3' ss Seq
GTTCTCTTTTCAATTCTTAGGAT
3' ss Score
9.77
Exon sequences
Seq C1 exon
AGTACAGAACAGGTGGCCGCATTTTGCCGCAGTTTGCATGAGATGAACCCCTCTGACCAGAGCCCATCTCCTCAGGACTCCACGGGGCCTCAGCTGGCGACCATGAGACAACTCTCGGATGCAGATAAGCTGCGCAAGGTGATCTGCGAGCTCCTGGAGACGGAGCGCACCTACGTGAAG
Seq A exon
GTATGTTTCTTTTTTCTCCCCCTGCCCTCCCTCTGCCTCGTAAAGGAGTGAAGTTGGTGTGTCTGCTGGTTTTCATTAACAGCTGATTTAAACTGTGTTCATGAAGAGCGTCTTGGTTTCTCCTGGAATTTTGCCTATACTCTGAATGTTAAAAGCTTGTTTTGAGTTGTTTTTTTTGTTTTTTTAAGATAGTCTCACTCTGTTGGCCAGGCTGGAGTACAGTGGTGTGATCATAGCTCACTGCAGCCTTTACTTCCTGCGCTCAAGTAATCCTCCCTCCTCAGCCTCCTGAGTAGCTGGGACCACAGGTGCATGCCACCATGCCCAGCCCCGTTTTCTGTTTTTTTTTGTAGAGAGGAGGTTTCACCATGTTGCCCATGCTGGTTTCGAACTCATGGGCTCAAGCGATCCTCCCACCTTGGCCTCCCAAAGTACTGGGACTATAGGCGTGAGAGCTACCACGCCCAGCCTTCTTGTGATTTTTAAGGAAGCCTAGTGATTTTCACGGCAATTCATTTATATATATATATATATGTATGTGTTGTTGACCTAATAAGAAAGCTACATTTAATTTTTTTAAAAGTTGAGGGTATGATCTTCATAATCTAATTAGAATCTAGCCAGAAGACTGCCAGGTCTGTTGTCTTTGTGTTATCACTTGTTCTGACACCTGGTCACATTTCCTATGCGAAAGCAGGGTGATCTGTTTAAGTATCTATATCTTAGTCTTTTAAATCAGGGGTTAGCAAACGACGGCTCTCAGGTCAAATCCAGCTCGCTGCCTGTTTTCGCAAATAAAGTTTGATGAGAACACAGCCACGCTCATTCCTTGACATATTGTCTATGCCTGCTTGGGTGCTACAGTTGAAGAAGTTGCAATGGAGACCGTATTTTAGTCCTCGAAGCCTAAAATATTGACAGAAAAGGTTGGCTTACTCCTGCATGAAATGGACCTTAACGACCTAAAGTCTCTAACGTTAGCCTTCGGGACAGGATCTGTTTGTTCTCTTCTAGATCCTTTTATAGACATTAACATATGCTTTATACTTTAAGTTCTAGGGTATATAAAAAATAAAACACATAAGCTAATGAGTTCTCTTTTCAATTCTTAG
Seq C2 exon
GATTTAAACTGTCTTATGGAGAGATACCTAAAGCCTCTTCAAAAAGAAACTTTTCTCACCCAGGATGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000156299-TIAM1:NM_003253:18
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.583 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0062115=RhoGEF=PU(6.8=21.7)
A:
NA
C2:
PF0062115=RhoGEF=FE(11.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TACAGAACAGGTGGCCGCATT
R:
CTCATCCTGGGTGAGAAAAGT
Band lengths:
247-1359
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)