HsaINT0179979 @ hg38
Intron Retention
Gene
ENSG00000134215 | VAV3
Description
vav guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:12659]
Coordinates
chr1:107760784-107765175:-
Coord C1 exon
chr1:107765076-107765175
Coord A exon
chr1:107760880-107765075
Coord C2 exon
chr1:107760784-107760879
Length
4196 bp
Sequences
Splice sites
5' ss Seq
GAGGTGCCT
5' ss Score
4.01
3' ss Seq
TTTTTAAAACATTTCATTAGGAA
3' ss Score
5.82
Exon sequences
Seq C1 exon
ATTGGTTATTTACGGGCAGTACTGCAGTGGAGTGGAGTCAGCCATCTCTAGTTTAGACTACATTTCTAAGACAAAAGAAGATGTCAAACTGAAATTAGAG
Seq A exon
GTGCCTATTTATTTTTAGTTTATGACATAAAGCAAAATAAACCTAAAAGCAATGTGTTCCTCTTTATGATCAGTGAAGCAGTACATTTCCCATTATTTTAAATATAATTTCATGTCAATTTTATAAAATATTTAAACAGCTCTATAAAATAGTAATATGGTAGTAATAGTAACAGTCGTTAAAAATCTAACATTTATGGCCCTGTGTTTTACATGCATTATCTCATTAGGTCCTTCTGACTCTGTGAAATAGGTACAATTAATTTTCTCATCTTATGAGAAAGCTGAAGTTCAGAGAGATTATGAATAACTTGCGTAGATAGTAAGAAGTGCAGGACGAGTGAGATACGTTAGATAATGTATATGTAGATTTAAAATGTTTACTAGTTAGCTGGGCAGGGTGGCTCATGCCTGTAGTTCTAGCTACCTGAGAAGTTGAGGCCAAGGAGTATGCACTTGAGCCCGAGAGTTTGAAGCTGCAGTGAGCTATGGTTGCACCATTGCACTCCAGCCAGGGTGGCAAAGCAAGACCCTGTATCAAAAACAAAATAAAAAAGATGTTTACTAAAAATATGACATTTAGAATCAGATGTATTAAAAGGCCATGCATATTGCCCACAGGAAGGAAGAGAAGACGAACACAAATATGGTAGGATTAAATAACATGTGATAAGCACTGTATAATAGGGCTCTGTAAGACTGAATCTACCCACTTCAGTGTGGGTAGATTGTAGAGGATTCATCTGAAGAGGCGCATTTGAGTTAGGTCACCAAAGAATGGGATGAGCTTTGACAGATGAGATTCTATGGAGAGCATTCCTGAACAATTGGTATGTATTGACCAGAACAGTTGGGAAAGTTTGAGAGGTGGCACGTAGGCCGATATAAACAGAGTGCATGATCACAACAGTATATAAGTCTAGAAACCTAGGTTAAGTCGTGTTTTTTTGTACATCATGTTTTTTTTTTTGTTTTGTTTTTTGTTTTTTGTTTTTTTTTTTCCTGAAGAGGAGTTCGAGGACTTCATGCTTTCAAAGAACTTTTGAACAATGTTTGTTGTATCAGTCACTGTATTATCCATGTATTTTGAATTTTATTAAATTTCAGGTAGAGATATATAGCCAGCTCTTAAATTTAACAGCGTGTGGCTTATTTGCCTGTTTAATATCCCTTTTCCTTTTCTTTGTTCAGTGTAGCACTGAGGTCAGGGGAGAAGGGGCAGGTGATTTTCAAATCAGAAGCCCTTCACTGTTTTGCCTCTCTGGCATGATTTCATAGCTCACAACTCCCACAAAGGGAAACTATTGCTTAGACAGTTTGCACGTTAACAGGCCACCAAGTAACTGTACTAGATACGTGATCTTTTTGCTTTATATCTTAATATTCCTTCATTATGTTGACTTTAAGACTGGAGGTAGTTTGAGTCACCCCTAAATAACATCCTTGTAACATTGTTAGTGCAAAGACTTCCTGCTCCTCTTTGCAGAATAGAGCCTCCTAAGTGTAGAGCTGGGAGCCACTGTGACTCAAAATATGATGATAAAATTAAATTTTACAACTTATACACCTACTTCCTAGTAGGGCAACATTAAAGCAGTTTTTCTTAAAATAAAGATATAAAATTGTGCTCCCAGATAGTAGTCAGCAAGTTGTCAATCACACCTCCATTATATTCTCAGTCTTGTTTGAGTGTTGTTCTTCCTTCTTTCAGAGTTATTGTCAAAGTTTTGCCCAATGACCATACTCTGGGACTCTAAGTATGTAGTTTTTGCAGTCAATGCTCGACTTAGGGAAAGAGAGGACATCAGGCTGAGTTTGAAAGGCACAGGGTGAGGTGCCCCTGCTGTCCTTTCTTCAGCTTAAAAGCCCACACTTCTAACCATAGTCCTGATTTGGAAGTATTAAGTCGGATACTTAGTGTAACACTTCAACAAATACTCAGTGGGAGCTGCGTGCCGCAAGCCCCAGCATGATAGAAGGAAAACTACCTTATTCTTGGTGTCTTTCTGCCTTCTTTGTGTCTTCTGTTTTGTGGTTATTTTTGTTCTTGTTGAGTTTTTTGTCTTTTTCTTCTCTACTTTGGAACCAAGATAACATGGGGTGAAGGGCGATGAATCTCTTTATCTTGCCCTATCAGCCTGGCTCATCCTACCTCATTTTATTTTCCATTACAATTGAATTGAGGCTAAGCAAGTGACTGGATGTTTTGGAAGGATTCTTTCTACCCATTATTTACTTTCAACACGAATAAGCATTTTACATTTGAGTCTCTATCTCCCAGGTGTAGCTAATTCCAGCAATGTTGGTTTCTTTACTTCCTGAGCCTGTAACTTAGAATGTAAAGGAACTGACTTTTTTTCTTCAACATTTTGAAACTAATTTCCATAATATAGTGAATTTTAAATATATAATATTTCTGTTCCTACCACTGTGTTGGGATGGCATAACATAAGAAATATAAGCTACAACCTTAATTCCAAGGGCCTTAAAATGCAGCAGAGGAGATAAGACCTACTAATTATAGTAATATTAACAATGTAACTTTCTGTTTGAGACCCATGATCCAGAGCTCTCTACAATCTGTAGAAGTAAGAAACTGGTTGAAATAGTTATCCTTCTAATGAACTGCAGTAATTGATGACACAGCTAGCATGTCAGGATGTGTCCCCAATTCATTTTGACTGATAGCTGTAGACAGACATACTCATTAAGTCACGGATCATTAGAGTTAATGGTGTTTTTTTGGAGCTCCTCATAATATATCATTCCATGTGCCAGAAAAACTAAGTGTGGGCAAAGAAGAAACAAACTTGTGAGCAACAGTGTATTTTCTTAAGCACAACTCCGTCTATGAACTGGAAAGGTCCTTGTGCTGGGATGTGCAATTGTGTCAGGATTTTGGACTTATGAGGTTGCTCACTAATAATAATATTTGTATGGCCCTTTTTTTTTTTTTTTTTGAAGAACACCATAGTTACGTGAGAAACAGTAAAATCAGAAAAGTGACTTGTCCAAGGTCACACCGCCAACAGTTGCCAAATCTTGGCTTTAAGTTCATTCTTTGACACTTCAAAGTAATTTACTCAAAGTCATAATTATTATCAAAAGAACAAACCAGTCAATACTATTTTAAAATAAACCTTTAGGAAAGAAGAGGGTGAAATTAAATACAATCCAAGGCTTCTAAATCTTGGAGTTTAGTAGTAGGTTTATACTTGAGCAAAGTTTTAAAGTCAAATATTCCATTTCATTCAGTTCAGTAAATACTTATTAAGCAAATACTACATTCTTAGGGGCATACAGCACAAATCATATTGGAGTAGATATTACATATGATAATAATTAAAAGACCCACAAGACAGAGAGAGAGTACACCCAATTGTGATTGTAATTGTTACGAAAGGCCTAGGATTGTAGTTCTTAAACAGGAAGATGTATTTTGCTGGAGGCTGGACAAAGCACATCATAGTTGAGGGAACTGAATAAACCATAGTTGAGGGTGGGAAGACTATTGACACTTTTGATGAGTAGGGATGTGTTCTTGATGCCTGTTCTATAAGTCCACTGGGGGAAATTGGTGGGAAGTACAGCGATAAAGATAAACTGAAGAAGACCCTGGGGGGCCATGATTTTGCACTAGAGAAAATAATTTTCTTTTTCTTTTTTCTTTTTTTTTTTTTTTTTGAGACGGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGACACCATCTCAGCTCACTGCAAGCTCCGCCTCCCGGGTTCACTCCATTCTCCTGCCTCAGCCTTCTGAGTAGCTGGGACTACAGGCACCTGCCACCATGACCGGCTAATTTTGTTTTTGTATTTTCAGTAGAGATGGGGTTTCACCATGTTAGCCAGGATGGTCTTGATCTCCTGACCTTGTGATCTGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCAAGAAAATAATTTTCATACACAAAATAGTTCTCTTTTATTCATGTTTAGAGTTAAAGTACTACAAGATTTGTTTTTTTAAATTGAAGATACTTTCTGTTATTTACAGAGAAGGATTGTTAAGGAAACAAACGCACTCATTTATTGTATAATAACTGTTCTGCCTAGGGCCTTTGCATCTTTTAATGTTTATGACTCCCTAACAAAGTGTTTTTAAAACATTTCATTAG
Seq C2 exon
GAATGTTCCAAAAGAGCAAATAATGGGAAATTTACTCTTCGAGACTTGCTTGTGGTTCCTATGCAACGTGTTTTAAAGTACCACCTTCTCCTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134215:ENST00000370056:9
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0062115=RhoGEF=FE(18.9=100)
A:
NA
C2:
PF0062115=RhoGEF=FE(17.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains