HsaINT0187905 @ hg19
Intron Retention
Gene
ENSG00000172888 | ZNF621
Description
zinc finger protein 621 [Source:HGNC Symbol;Acc:24787]
Coordinates
chr3:40567270-40570936:+
Coord C1 exon
chr3:40567270-40567355
Coord A exon
chr3:40567356-40570809
Coord C2 exon
chr3:40570810-40570936
Length
3454 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGC
5' ss Score
9.6
3' ss Seq
GCAGGAACCTGTTGTTTCAGGAG
3' ss Score
2.62
Exon sequences
Seq C1 exon
CTCTTGAGGATCTTGCTTGTCCAAACCCAGAAGACAGTGCATGAAGCCAGGGGACATCCGCCATGCTCCAAACAACTTGGCCTCAG
Seq A exon
GTGAGCTGAGCTTCTTTCAGTTTTTTTGTTTGTTTGTTTATGTTTTTTTACTCACATTAGCTATCAGATAATCAGGAAAGGATGAGGAAGGCCTAACTTGGCCAAGCTGTGTTTTCCCCTTTGTATCTATCTCCAGGGCTATGGCAGATGTAAATATGTGCTGGGGAAATGAAAGTTTTGTGTATAGAGAGTGATGAGTTTGGATGTATAGATTTAAATGGAAGAAAGGGGACCTATACCAAGAAATTCTTTCTGAATGTGGAAATCCAGATCGTGTTCTAGAAATGAAAGTCACCTACTGAAATCAGACTCATTTTTTGTGAGACGGAGTCTCACTCTGTCGCCCAAGCTGGAGTGTAGTGGCACTATGATATCGGCTCACTGCAGCCTCTGCCTCCTGGGTTCAAGTGATTCCCATACCTCAGCCTCCTAAGTAGCTGGGATTACAGATGTGCGCCGCCACGTGTGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTACACCACGTTGGCCAGGCTGGTCTTGAACTCCTGAGCTCAGGTGATCCACCCGCTTCGGCTTCCCAAAGTGCTGGGATTATAGGCATGAGCCACCGCACTAGCTTGAAATCAGAAATTCTTTATTGGAGAGATTGCCCACAAATTGTATTGTATGTATCCCAGAGAGACTAGTATTGTTGCTTTAATATACATTTTCTAAATGCTAGATGCAAGGACTCTGAAGTTGCAGAGAAAGCTGGATGTACTCTAGAAACTGGAAGGGGTCAGAGAAAGTGGTTCAATATGAGATGGAAGAAATAGATACCTGTATTATAGGTCATGGTGAGGACAGTGGTTTCTGTACTGGTTCATTGGGAAGGCACTGAAGAATTTTAAGCAGGGGGATGACATGGTTGGATTTACATATTAAAAAGATTTTCCTAGCCCTTAGTGGCAAATTGATGGTAGAAAGGTGTTGGTCAATTAAGAAGATATTAAGTGTTGTCCTTTTATTTTTTTTGTTTTTGAGACGGAGTTTCGCCTTTGTTGTCCAGGCTTGAGTGCAATGGCGCTATCTCGGCTCACCGCAACCTCCACCTCCCAGGTTCAGGCAATTCTCCTGCCTTAGCCTCCCAAGTAGCTGGGATTACAGGCATGCACCTGTTTTTTGTTTGTTTGTTTGTTTTTTTGAGATGGAGTCTCACTGCAACACCCAGGCTAGAGTGCAATGGTGCGATCTTCGCTCACTGCAACCTCCACTTCCCTTGTTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGATGGAATTACAGGTGCCCGCCACCACGTCCGGCTAATTTTTGTATTTTTAGTAGAGACGGGGGTTCTCCATGTTGGTCAGCTGATCTCGAACTCCCGACCTCAGGTGATCCGCCTGCCTCAGCCTCCCAAAGTGTTGGGATTACAGGCGTGAGCCACTGTGCCTGGCAAGTGTTGTCCATTTTTAAATTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGCCACCCAGGCTGGAGTGCAGTGGCATGATCTCAGCTCACTGCAACCTCCACCTCCCGGATTCAAGCAATTCTCCTACCTCAGCCTCCTGAGTAGCTGGGATTACAGGTGCACACCACCATGCTGGGCTTATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGCATTTTACTTTTTAATGTAATTAATTTATTTGTAGTTTTTATTTTCTGGAGCAGTTTTAGGTTCACAGCAAAATTAAATGGAAGGTACAGAGATTTCCCATATATTCCCTGCCCCTACACATGTATATACAAGTTCTGATAGAAGTTCAAATACAAGTCTGGTATCAGCACAGTAAAATGTCAGTGTCTTTAAAAGAATGGAAATGCTTTTTTTCTTTCCTTATTCTCTGATATGTCCTAAACAGCATATGTGGTTTGATTGAGAAATAACTTACCCTGAAACGATTCAACACTGGTACTTAAAATAGTTTTTTAGAGCAGTTTTAGTTGATAACAAAATTGGGCAGAAAGCAAGAGTTCCCATTTATCTCCTGCCACCACAAAACACACAACCTTCTTCAATATTAATATTCCACACCAGAGTAACACGTTTGTGACAAGGAGTGAACCTACACTAACACATCATTGTCATCCAAAGTTGATAGTTTACATTAGGGTTCACTCTTGATGGATGACACATATCCACTATTATAGTATTATATAAGCAGAATAGTTTCACTGCCCTAAAAATACCTTATGCTCCTCTTATCCATCCTTACTTTCCCCTTAGTCCCGTCCCAATTGACAACCATCAATTGATTTTTGTATTCTCTTCATAGTTTTGCCAGTTCCAAAATGTCATATAGCCAGAATCACACAGTACGTAGCATTTTCAGATTGACTTCTTTCATTTAGTGGTAATGCATTTCGTTTCCTCTGTGTCTTTTCATGGCTTGATAGATCGTTTTGTTTTAGTGCTGAATAATATTCCATTGTCTATATATACTACAGCTTATCCATTCACCTACTGAAGGACATCTCGGTTGCTTCCAAGTTTTGGCGATGATGAATAAAAGCCCCTGTAAATGTCCATGTACAGGTTTTTATGTGGACATAAGTTTTCAACTCCTAAATTTAGTTAAGCACCAAGGAGCATGACTGCTGGGTTGTATGGTAAGAGTGTGTTTAGTTTGTAAGAAATTGACGAACTGTCTTCCAAAGTGGCTGTCCCATTTCGCATTCATTAGCACCAGCAGTGAATGAGAGTTCTGTTGTTTCACATCCTGGCCAGCATTTGGTGTTGTCAGTGTTTTGGATTTTGGCCTTTCTAATAGGTATGTAGTGGTGTCTCACTGTTTTTATTGCAATTCCCTAATGACATATAATCTTGAGCATAGTTTCATATGCCTATTTGCTATCTGTATATTTGCTTTGTTGAGGTGTCTGTTGAGGTCTTTTGCCTGTTTCTTAATTGGCTTGTTCATAAAGAGTTCTTTGTACATTTTGGATAATAGTGCTTTATCAGATATGTCTTCAGCAAATATTTTCTCCTAGACTTTAGCATGTCTTCTCATTTTCTTAATGTGTTATCCTTTTAAAATACAGTTTAATTCCCCCTCATTTTGTTTTCAGTTGTTTTCTCCAAAACATTGTTTGCTAGTTTTTCACACATGCCTGTAATCTCAGCCTGGGTGCCAAGCTGTAAGAATCAGCAGCAGTTACGGGCTCCAGAGCTGGGTAGATGGGAGAGTGTTGGGGCTCCCCATTTGAAAGTGGAACTACTGGCTGAGGGCTCGCCCCTGGCTGTGGTGGTGGGTGTTCTTGTTGAGCAGACCTTACATGGGGCTCAGAGTTGTGGATGCAGGCAGGTTTATCCCTTCCCTGAAGCTCAAGCTGCTCCCTTCTTCCTTCTACTTCTCACTCAGAGATTGAGCAGGAACCTGTTGTTTCAG
Seq C2 exon
GAGTCAGTGACCTTTGAGGATGTGGCTGTTTACTTCACCCAGAATCAATGGGCCAGCCTCGACCCTGCGCAGAGGGCCCTGTACGGGGAGGTGATGCTGGAGAATTATGCAAATGTGGCTTCTCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000172888-ZNF621:NM_001098414:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF066386=Strabismus=PU(2.0=12.5)
A:
NA
C2:
PF0135222=KRAB=WD(100=95.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)