HsaINT1003176 @ hg38
Intron Retention
Gene
ENSG00000204305 | AGER
Description
advanced glycosylation end-product specific receptor [Source:HGNC Symbol;Acc:HGNC:320]
Coordinates
chr6:32182247-32182698:-
Coord C1 exon
chr6:32182568-32182698
Coord A exon
chr6:32182389-32182567
Coord C2 exon
chr6:32182247-32182388
Length
179 bp
Sequences
Splice sites
5' ss Seq
GATGTGAGT
5' ss Score
7.77
3' ss Seq
CTCTCCCCTTCCCCCACCAGGGT
3' ss Score
11.16
Exon sequences
Seq C1 exon
AGCCTGTGCCTCTGGAGGAGGTCCAATTGGTGGTGGAGCCAGAAGGTGGAGCAGTAGCTCCTGGTGGAACCGTAACCCTGACCTGTGAAGTCCCTGCCCAGCCCTCTCCTCAAATCCACTGGATGAAGGAT
Seq A exon
GTGAGTGACCTGGAGAGAGGGGCTGGGAGGTAGGGTGAACCATAACTAGCAACAGGGAGGGCAGAGGGCTAACGAGGGAAAGGCAGGCTAGGAGCTGAGGAGGAAGAGAGGGTATCTGAAGATATGGAGACAAAAAGACAAGGGTTTTGAAATAGTCTCCTCTCCCCTTCCCCCACCAG
Seq C2 exon
GGTGTGCCCTTGCCCCTTCCCCCCAGCCCTGTGCTGATCCTCCCTGAGATAGGGCCTCAGGACCAGGGAACCTACAGCTGTGTGGCCACCCATTCCAGCCACGGGCCCCAGGAAAGCCGTGCTGTCAGCATCAGCATCATCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000204305:ENST00000375076:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.743 A=NA C2=0.736
Domain overlap (PFAM):
C1:
PF138951=Ig_2=PU(44.0=84.1)
A:
NA
C2:
PF138951=Ig_2=PD(91.8=93.8),PF066977=DUF1191=PU(27.7=64.6)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAATTGGTGGTGGAGCCA
R:
CGATGATGCTGATGCTGACAG
Band lengths:
251-430
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains