HsaINT1005386 @ hg38
Intron Retention
Gene
ENSG00000204256 | BRD2
Description
bromodomain containing 2 [Source:HGNC Symbol;Acc:HGNC:1103]
Coordinates
chr6:32971595-32974765:+
Coord C1 exon
chr6:32971595-32972927
Coord A exon
chr6:32972928-32974461
Coord C2 exon
chr6:32974462-32974765
Length
1534 bp
Sequences
Splice sites
5' ss Seq
TAAGTACGT
5' ss Score
5.1
3' ss Seq
TTTTGTTCCCATCTTTACAGGCT
3' ss Score
10.3
Exon sequences
Seq C1 exon
ATTCTTCGCTGCTGCTGCCTTACCGCCGAGAACCACCACCCGCCAGGCGTCTTGCGGCCACACCCCTGGCGGGTTCAGGCAGGCTACGCCCACGCGACCCCTCCCGTTTCCCTGCTTTGGCCAATGGAGGAGCTACGAATGGCACGACCTGCTCGAGCTTGGCAGTCTCCAGTTGGGCTGTGCATGGAAGCTTGGGAAGACTTTGTTGGAAGGGGAGGCGGGGAGAGAGTGCTGGAGGCTCTGGGGCGATGGCTTCCGCACCTCTTCCAACCACCCTCTTTCCCTGGAGTCGGCGGACCACAGCTCAGCCAATTGGCTTGGAGATGTGGCGGGTTGCCACTTCCCTGTGGGTCTCTGCGGCACTCTTCTGCCTGGTGACTGACACCTTGGAAATGAAGTTTATGACGTCATCGTTGCGGCTGGCCAATAGAAAAAGCTCCCGCGGAGAGGTGTTCCTTCCCCTTCGACTCAGCTTCTTCACCCGCGTGAGCGAGCGCGCGCGCGCGGAGGGGGTGGGGAAAAGCTCAAGCAGGGTGGCGCGCATGAGCGGCGAAGCTCCTCCTCCCCGCCTATATATAAAGGGCTGGCGCGGGGCTCGGCGGCGCCATTTCGTGCTGGAGTGGAGCAGCCTCTAGAACGAGCTGGAGGATTCTGCCTACCGATACAGAGCCTTCGAGTCGTCCGGGGCCGCCATTACAATCCACCTCCATCCGCTTGGAAATGGCCTTCGTCCCGGCCTATGACTGGTCCCAGCGGGCAGTACAGACCCCCTAGAAGCCCCTGGAGCTCCCCTTTTTCGGGCCCCGCCCAATCCTCGGAGTCTGTCCACCCCCTCTACTCCGCCCTCAAGAGGATTTCAAAGATGGAGGCGGCGGCTCCCTAAACCACTTTTCGTGTTCATCCGCCTCCATCCGAGATCGAAACGGGACCTCGTCGGCCCCGTAGGGGCCCGACAAGAAGAGGGAATCCCTGCAGACCAACAGCGGGCTATATTGACGACGGTGTCTGAGATCGGGGACCGTCTTTTGAAGAGTCAGTCCCTCCTTAGTTGCCCGCCTCAGCTGAGGCCGCCGCCATTTTCTTGCTGTCCGCCGTCTGCAGAGCGCGCCAAGCTGCCCGGAGCTCTCCGAGAGGCCCCAAAGAGACTGCTTTCGTGCCGGCCAGGCAGGGGGTTTGTCGCCTGGAGGCCCAAGAGGAACGGCCTCCCCCCAACTTAGCGGGTTATGCTGGACCGGGCGGTGAGGGGAACCGAGGCCACCCGGACTTTCCGCGGCTGAGGGCAGCGCCGGTTCCTTGCGGTCAAGATGCTGCAAAACGTGACTCCCCACAATAA
Seq A exon
GTACGTTTCCGCGAGCCGCGTGTGGGAAGGGGATGTTGCAGGGCGGCGGCACAGGGGTGTGGGGCGCCGTGTTGGGAGTACTGAGCGGCCCCGGCGCGCTGCTGTTGCGGCGCAGCTGTCGACTCGGTCGCGCGGAGGGAATTGAGCGACGGTTTTGGAACGGTGGTGGCGGCTCGGCTACTGCTCGTGGAGGGGAATACAGGTTGTCAATTTATACGCTATTAATGCCGCCGTGGCCCAGTCTTAACCGAGTCAGGCAGAGCTAGTTTGACGGTGGAGTGGAGTGAGGTTGAACAGCAGGTTTGGCGTTTGGTGGGTCTGGTATCTAGCGGCGGTCTGTTAGCCTTTTAGGGGGGATTCACGGACACCTCTAGCGCCCTGTAGGGTTGCCATGGTGACGGAGCGCTTAAGGGACTGGCAACGGGGATTCCCAGAGAAGGGTAAAGGGATCACTCTCCCGTGTGTGCAGGTTCCTAATGCCCAGGGTATGTCATTAAATCTTTTGCTTTCTTTGGGTGGGTGGGTTGTGTGTGGTGTTTGTTGGTGCAGGGATTGTTTTTTCCTAACATTAAAAGTTTGATTCAGGGCAGGAGGGTAGAGCTAAGGTTCCTAGTTCAGCTCTGCGATGTAAACAATGAGATTCCCATATGATGTTTTAATTCTTAGGTGGTAGGAAAGACTGATCGGAGGAGCACCAGAGGGACTGTAAATGAACCACTGTTAGCGTTTGGTGTCCGGAGTTGGTGCTACAGGGGGAACTGGTAGTGGAATCGTGTTGTGTAGTGGGTGGGTGGAAGGGGGCTATCACTTGGTGACCTTGACTGTTTTGTACGGCTTTTTGACTTCCTTGGAGTGAGGAGACTCTGATTTGGTGCGAATAATTTTGAGGGCCTGGAAGTTACGGGCTGTGAAGTCTGACAAATTCTTCCTTGTCTGAATTTGTTTTTAAGTTGATATGGTTCTTCCTCTGGGTTTCTAGTCTATGTTCTGTTGTGGCGTGAACTACCCAGACCTTGTGGAAGATGGTGCTCTCTCTTCTATCTAGGTGGATTATTCTGTGTCTTATCAGCATTTTATGGAATTTTTTATAGCCATAATTTGTTCTTTTCCTCCTTACCGGCGCTCAACCACCATGGCAACCACCAAACCCCTAGTGAGGAGGAAGCTTGGGGTTTGAGTTTCTTAACTCCACCCATTTTGCTTAAGCCCCATCCCCATAGGGCTGTAGTTCTGAGATGTCGTGCCTTGTCAGAAACAATTTGGGAGTTTTTTAAAATATGAAAAAGAACAGATAGAGCCTATCAGACTTAAGAAGGTGGGATCTAGATAGTATACTAAAAATATTAATAAAAGGAAGGCGGGGCCAGCAATAAAAGCTCCACAGATTGTTTGGATATTGTTTCTGCTTAAGAAGCACTTGGCATAAGCTTAACCACCTCACTAGGGCCAGCACCTGGATTCATCAGACTATTGTGCAGATGCACTTTTTCCTCATTTGGACGATATTGCCCTAATTTTGTTCCCATCTTTACAG
Seq C2 exon
GCTCCCTGGGGAAGGGAATGCAGGGTTGCTGGGGCTGGGCCCAGAAGCAGCAGCACCAGGGAAGAGGATTCGAAAACCCTCTCTCTTGTATGAGGGCTTTGAGAGCCCCACAATGGCTTCGGTGCCTGCTTTGCAACTTACCCCTGCCAACCCACCACCCCCGGAGGTGTCCAATCCCAAAAAGCCAGGACGAGTTACCAACCAGCTGCAATACCTACACAAGGTAGTGATGAAGGCTCTGTGGAAACATCAGTTCGCATGGCCATTCCGGCAGCCTGTGGATGCTGTCAAACTGGGTCTACCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000204256:ENST00000374825:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.584 A=NA C2=0.412
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0043920=Bromodomain=PU(31.8=26.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCGGTCAAGATGCTGCAAAAC
R:
CGGTAGACCCAGTTTGACAGC
Band lengths:
342-1876
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains