HsaINT1007683 @ hg38
Intron Retention
Gene
ENSG00000120903 | CHRNA2
Description
cholinergic receptor nicotinic alpha 2 subunit [Source:HGNC Symbol;Acc:HGNC:1956]
Coordinates
chr8:27462979-27467338:-
Coord C1 exon
chr8:27467229-27467338
Coord A exon
chr8:27463994-27467228
Coord C2 exon
chr8:27462979-27463993
Length
3235 bp
Sequences
Splice sites
5' ss Seq
CAAGTAGGA
5' ss Score
4.46
3' ss Seq
AGCTCCTCTCCTCTTCTCAGTGC
3' ss Score
8.2
Exon sequences
Seq C1 exon
GAGTGGAGCGACTACAAACTGCGCTGGAACCCCACTGATTTTGGCAACATCACATCTCTCAGGGTCCCTTCTGAGATGATCTGGATCCCCGACATTGTTCTCTACAACAA
Seq A exon
GTAGGAAGCCATTGGGGTCCTGGGGGGATGAGGGGAGGCCAACTTGCAGGGGCCGGGTCCATGGCCTTGGGAGGGGCCCCCCTGGTGTCAGCTTCCTCGCCTCCTTCTCGACTGCTGTGCTGAGCATGCCTCCCCTACCTCTCTCTCTATTCCTTCATTTCTTTCCTTTTGTTCTCACTCTACACCAAAATGAATGGCAGCTGAGCACCTTTTAGGTATCAGTGCCTGGCACTGTGCTAGAGGGACAGAGATTTGTCCATACTGAGTATTCTTTGAAAAATTTGGTGCAGGCTCAAAAAACAATACCTTGGGGTTGAAGTTGTGAGGGGTGGCAGTGTTGTTCAGACAGGCAGGCAGCATCGGGCCAGCACCTTCAAAGGGCATGTGCTCACTTGGTATGCAGTTTCCTTTTTCCCAATCATGTTGTTTTGTAGTTGTCTTCAAGACTAAAAAGGAGTAATCTTTGACCACAATGACAAGAAGTTAATAGAAGGCAGAGGAGTCTAAAGAGAGCCCCAGGGGACAAAAATAAATCAATAAAAAATATTTTGATGGAATAAATAGACATCTATAATTTCATTTCTGTGTTTGGTATCAGACAATTCTTCCCTTAGAAGTAAAGAAGTTAAAATGAAAAGATATTTGGTGTTATGTTCATCTAAAAAGGTTTTCTAAGGTGGGGCTGTAAGGAGCATGGCTTCTTTGAGTTATAAATAGGTATGAAAAAGGGTTCTGTGGTCAAGTAATTTTGGATAACATTGTATGTCACAACACCCACCCCCATCCCCACCCAAGTCCTTTGGAAAATGGCAGAGCACAATAGCATTTTAAAAAATGTTATTTGAAGTTCTGCAGCAAAGACACCCACCTAGCCCAGCATTTCCCAATTCATTTGATCCTACTTTGGAAATGCTATCTTTAAAGAAAGAAATAAAAGGAAAAACAACCCATTTCTGGATTTTGTGTCTTCAGATGGGTCAGATTTTTTTTTTTACACCGTCCAGTTCTGGTCAGAACTACGCCCTTGCACCTAAGCCATTTTGGGGAACACGTGTTCATCCTGGGTTCTTACACTGGCCGCTCTCACACAGCAGGTGCCTAGTGTTTGCAGCTGCTGCAGGACTCATGAACTCCCCACCCTGTCGTATCTCTGTGCCCCATAGCTGGCACCCAGGGTCCTTCTAGTTTCCACTTCCTGTACATGTGGCAGAGGTCAGGAGCAAAGTCCTACATCAAATATGACTTCGAGTTTGACAATTATCCAATAAGACTTCAGCCGGTGTTACCTGATTTATTACAAGAAATGTTGGTGGGGGACAAAATTCCAAGCCGAAGTCTTGCTTACATTTAGAGATGGATCCCCTCCACCCAGATACCCCACTCAAGGTTAAGAGGAAGGCATCTTAGAGTTTGCAAGGTTCCTTCCCCCAAGTGAGCACATGTTGCCATCTAGTGGTCATTGTTTGTGATAAACAAAATGCTTAAAAATTTTTTGTTTTTGCCTGGGCGCGGTGGCTCACACCTGTAATCCCAGTACTCTGGGAGGCCGAGGCCGGCGGATCAGGAGGTCAAGAGATTGAGACCATCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCGGGTGTGGTGGTGGCACCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGCAGAGGTTGTAGTGAGCCGAGATCACACCCCTGCACTCCAGCCCGATAACAGAGTGAGATTCCGCCTCAAAAAAAAATTTTTTTTAACTTTTGTCTCAATGTATTTGTTACTCCCTTTCAAAGTTCCTATTTCCAGCCTGCCCATATCTCTACCATGGAACTACTCCATGGGGGAAAAAAGCCCCCTGTTCCCAAGTACTCTTCTGATTTCTTGGATTTTAGGATTGACTGTGGGAATTAGAAGGGGAGGGAGGATGGTTAAAGACTAGAGCAGGAGCCCACCGAGCCACCTCCTGGTGGAATCAGGGGCTGAGGCTTCCAGGAAGTGCTACCTGACTGGTCACCACTATTCCAGTGTCCCCAGACTCCTTGTGGGTCCTTGAATGCCTAGTCCCACGATACCCCTGATTCACACTCTCTGTCCCTGTGTGACCCTCTACTGGAAGGCTCTCTGCCCATTTCTCAGCCAAATCCTACCATCAGTCAAGGCCTTTTGCAAACGGCAGGCTTATCGATGACCCTGCTCACCTCCCAGAAGGGAGTTTTCCCCCAAAGGGTCTGGGGAGCACCCAGACTGCCCTCTTAGTGTTGCCAACTGCCTGCCTGATGTTGCAGTGGTTCCTGGAGACGTCTCATCTCCTCATGGCTCCTTAAAGGCAGGGACTTTTCTCATATTCCTCTTCTGCACAGCTCTGGTACAGGCCCTAGCGGATGAGGGGCTCAAAAACGCATGTTAAATGGATACATTCAAGGTAGTATCTTCACCCGCAAAGGTGTTAGGTCTCTTCTGAGCAAGGATGATCCCAGGTGGAAAGGGATCGCCCTCCTAAGGGACCGACTCATCATCTGCTAGGGAAGAAAAACAGACTCATAGATATCACTCTAATATATTAAATGATCAGCTCGCAGGAGGACAGCTTTGACCCCCTGTGATGTCATCCCCACCCAGCCAATCAGCAGCAAGCACCTGGCCACACCCACCCCTTCCCCAAAACTGCCTTTGAAAAACCCCTAACACGCACGAACTTTGGAAGAGATGCTTTGAATGCTATCTCCTTCTCCCCCGTGGCGTGGCTGGCCTTGTGTCTATTCAACTCTTTCCTTACTGCAAATAAAATAAAATATTAAATGAATAAAAATAGGCAATCAAGCAACATATACCCCATGATCACAAATATATGATTGTCATATACTGATAGATTATGTATATATAATCGTTTTACATTTTATATATATACATATATATCATCAAAATGTTATTAGTGGTTGTTTTTAGAATTCTTGGTACTTCCTTCTATTCCTCACAATTCCTCCTTTTGTATTTAAAAAGGTAGTAATTGACAAGACAGCTCAGTGGCTATAAATGTGCATGCCGGGGGAGACTTACACACTTGCATAAATAAACCCCGCCAGTGTGGCCGGGTCTGACTTGGTTCTTCGGGTTCCCCTGCTGCCAGCTCTCTGAGTAGCCTGGCTCAGGCAGGTGGGTGTGCAGGGGTCTCCCCAGCTCCTCTCCTCTTCTCAG
Seq C2 exon
TGCAGATGGGGAGTTTGCAGTGACCCACATGACCAAGGCCCACCTCTTCTCCACGGGCACTGTGCACTGGGTGCCCCCGGCCATCTACAAGAGCTCCTGCAGCATCGACGTCACCTTCTTCCCCTTCGACCAGCAGAACTGCAAGATGAAGTTTGGCTCCTGGACTTATGACAAGGCCAAGATCGACCTGGAGCAGATGGAGCAGACTGTGGACCTGAAGGACTACTGGGAGAGCGGCGAGTGGGCCATCGTCAATGCCACGGGCACCTACAACAGCAAGAAGTACGACTGCTGCGCCGAGATCTACCCCGACGTCACCTACGCCTTCGTCATCCGGCGGCTGCCGCTCTTCTACACCATCAACCTCATCATCCCCTGCCTGCTCATCTCCTGCCTCACTGTGCTGGTCTTCTACCTGCCCTCCGACTGCGGCGAGAAGATCACGCTGTGCATTTCGGTGCTGCTGTCACTCACCGTCTTCCTGCTGCTCATCACTGAGATCATCCCGTCCACCTCGCTGGTCATCCCGCTCATCGGCGAGTACCTGCTGTTCACCATGATCTTCGTCACCCTGTCCATCGTCATCACCGTCTTCGTGCTCAATGTGCACCACCGCTCCCCCAGCACCCACACCATGCCCCACTGGGTGCGGGGGGCCCTTCTGGGCTGTGTGCCCCGGTGGCTTCTGATGAACCGGCCCCCACCACCCGTGGAGCTCTGCCACCCCCTACGCCTGAAGCTCAGCCCCTCTTATCACTGGCTGGAGAGCAACGTGGATGCCGAGGAGAGGGAGGTGGTGGTGGAGGAGGAGGACAGATGGGCATGTGCAGGTCATGTGGCCCCCTCTGTGGGCACCCTCTGCAGCCACGGCCACCTGCACTCTGGGGCCTCAGGTCCCAAGGCTGAGGCTCTGCTGCAGGAGGGTGAGCTGCTGCTATCACCCCACATGCAGAAGGCACTGGAAGGTGTGCACTACATTGCCGACCACCTGCGGTCTGAGGATGCTGACTCTTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000120903:ENST00000407991:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0293118=Neur_chan_LBD=FE(18.8=100)
A:
NA
C2:
PF0293118=Neur_chan_LBD=PD(59.9=33.9),PF0293211=Neur_chan_memb=PU(86.7=63.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains