HsaINT1007693 @ hg38
Intron Retention
Gene
ENSG00000147432 | CHRNB3
Description
cholinergic receptor nicotinic beta 3 subunit [Source:HGNC Symbol;Acc:HGNC:1963]
Coordinates
chr8:42731667-42737407:+
Coord C1 exon
chr8:42731667-42732549
Coord A exon
chr8:42732550-42736483
Coord C2 exon
chr8:42736484-42737407
Length
3934 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
3' ss Seq
CATCTTTTTCTCTTTTGCAGGTA
3' ss Score
13.42
Exon sequences
Seq C1 exon
TGCTGACGGCCGCTTCGAAGGCTCCCTGATGACCAAGGTCATCGTGAAATCAAACGGAACTGTTGTCTGGACCCCTCCCGCCAGCTACAAAAGCTCCTGCACCATGGACGTCACGTTTTTCCCGTTCGACCGACAGAACTGCTCCATGAAGTTTGGATCCTGGACTTATGATGGCACCATGGTTGACCTCATTTTGATCAATGAAAATGTCGACAGAAAAGACTTCTTCGATAACGGAGAATGGGAAATACTGAACGCAAAGGGGATGAAGGGGAACAGAAGGGACGGCGTGTACTCCTATCCCTTTATCACGTATTCCTTCGTCCTGAGACGCCTGCCTTTATTCTATACCCTCTTTCTCATCATCCCCTGCCTGGGGCTGTCTTTCCTAACAGTTCTTGTGTTCTATTTACCTTCGGATGAAGGAGAAAAACTTTCATTATCCACATCGGTCTTGGTTTCTCTGACAGTTTTCCTTTTAGTGATTGAAGAAATCATCCCATCGTCTTCCAAAGTCATTCCTCTCATTGGAGAGTACCTGCTGTTCATCATGATTTTTGTGACCCTGTCCATCATTGTTACCGTGTTTGTCATTAACGTTCACCACAGATCTTCTTCCACGTACCACCCCATGGCCCCCTGGGTTAAGAGGCTCTTTCTGCAGAAACTTCCAAAATTACTTTGCATGAAAGATCATGTGGATCGCTACTCATCCCCAGAGAAAGAGGAGAGTCAACCAGTAGTGAAAGGCAAAGTCCTCGAAAAAAAGAAACAGAAACAGCTTAGTGATGGAGAAAAAGTTCTAGTTGCTTTTTTGGAAAAAGCTGCTGATTCCATTAGATACATTTCGAGACATGTGAAGAAAGAACATTTTATCAGCCAG
Seq A exon
GTGAGTAAACTGGTATTCCTGATAATGCTGCCGTAAAGGTAGGCCAAAGACAAATATTTTGACATCTGTTTACAATAAAATATTGTCATGGTTTAAATGTGACGTTATATAAGACATGCTTTTTATACATATAACATTTAAAGCAAGCCCTGACATAACATAGCGACATTAGTATGAATTTTTAGGAAGTAGTTCACAAAAACATAAGGAGCAAAAGTGAAGCAACTGTTGATTAAGCAACTGTTGATTAAGCATTGTTTCTTATAATTCTATATTAAATAATTCAATTACACATTTTAAGTTGGTTAGCCTGGTTTCTGGTAATTTATCTTTCATTTTTCATTGGATGATAAATATGTTCAACCACAGTATTTAGAAATAAAAGATCAGAAAGAATGAGATTTTTAAATTAATATAAAATGTAGTGTTACAACAGATATTTTGGTGAGGAAAGAGGATGTGGTTATTTAGTTTACAGATTTTTTTTTTTTAAGTGTGAGCCAGGCACAGTGGCTCATACCTGTAATCCCAGCACTTTGGGAGGCCAAAGCGGGTGTATCACTTGAGTGCAGGAGATCGAGACCAGCCTGGACAACATAGTGAGACCCTGTCTCTACAAAAAATTTAAAAATTAACTGGGTGTGGGTGGGCGTGCTTGTCCTAGCACTTTGGGAGGCTGAGGCAGGAGGATGACTTGAGGCCAGAATTGAGACCAGCCTGGGCAATAAAGCAAGACCCTCATCTCAGAAAAAAGAAAAAGAAGATAAAAGAGAAGGAGAAAGAAAAGAAGTAGCGTGGGAAGAGTGTGAATTTCAGACTGAAAACAGTCCTGGGTTCAGATCATAATCTGAATGACTTAAGACAAGTTACTTAACCTGAGCCTCAGTTTTCTGAATCCTACCTTGAAAAGTTTGTGTGAGGATTAAATGACATAAAATACAAACATGCACAGTGTACCCAGCACACAGGGGCTCAGCTCCGTTGTATAAGCAGTCAACAAGTGTGAATTCTCGCCTTTCTAATTATCATCCTCATCCTTCTTCTTTTTTTTTTTTTTTTTTTTTGAGAGGAGTCTTGCTGTCACCCAGGTTGGAGTGCGGTGGTGTGATCTCAGCTTACTGCAACCTCCGCCTGCTGGGTTCAAGCGATTCTGCTGTCTCAGCCTCCCAAGTAGCTGGGACTACAGGTACACACCACCACACCTGGCTAATTTTTCTTGAATTTTCATTAGAGATGGGGTTTTGCCATGTTGGCCAGAATGGTCTCGAACTCCTGACCTCGGGTGATCCACTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGTGACCAGCCCATTCTTCTAAACAGTCCTTCCCCAGTGGAATGAAAATATTATTTGACGTGCAGATATTAAGCGTAAAAAGTGATCTGTTGGGCCAGGCACGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGAGTGGATCACGAGGTCAACAGATCAAGACCATCCTGGCCAACGTGGTGAAACCTGATCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGGTGGGAGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCACTTAAACCTGGGAGGCAGAGGTTGCAGTGAGCTGAGAGTGCACCACTGCACTCCACTCCAGCCTGGCGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAAAGTGATCTGTTGCCTAAAGCAAGTTACATATTTTCAATTTATATGAGAACTTCAATTTATAGGGTTCAAATATTTTACTCTAAAATTGATGAAAATTAGTGCCAAGAGCCTGATCCCGTAAACAAACTGATGAAAGAATTTTTTTTTTTTTTTTTGAGATGGAGTCTCGCTCTGTCACCGAGGCTGTAGTGCAATAGCTCGATCTCAGCTCACTGCAAGCTCCACCTTCCGGGTTCGTGCCATTCTCTAGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCCGCCACCACGCCTGGCCAATTTTTTGTGTTTTTAGTAGAGACAGGGTTTCACTGTGTTAACCAGGATGGTGTCGATTTCCTGACCTCGTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCCTGAGCCACTGCACCTGGCCAAGAATTTTTTTTAGAAATATCCTTCTACATTTTCTCTTGCGTTCACAGACACTGCCTCATATGTCCTCTCTCTTAACAATCTGTCATGTTTTTCATCCACTTAAAATTGTTTTTAAAAGCACTAGAAAAGTGACTGCTGCTAGACAAGAAACATTCAGCTGTCAAGTTGGGAGAATTTTTTTGTTTGTTTCTTAACATCTTTTAAAAACACTAATACAGGGCCAGGCGCGGTAGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGACGGAGACCATCCTGGCTAACAGGGTGAAACCCTGTCTCTACAAAAAATACAAAAAATTAGCCGGGCGTGGTGGCCGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGTGTGAACCCGGGAGACGGAGCTTGCAGTGAGCCAAGATCATGCCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCCGTCTCAAAAAACAAACAAACAAACAAAAAAACACTAATACAGGCCGGGTGTGGTGGCTCACGCCTGTAATCCTAGAACTTTGGGAGGCCGAGGCGGGTGGATCACCTGAGGTCAGCAGCTCGAGACCAGCCTGGCTAACACGTTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGCATGGTGACGAGTGCCTGTAATCCCAGTTACTCGGGAGGCTGAGGCAGGAGAACCACTTAAACCCAGGAGGTGGAGGTTGCAGTGAGCCAAGATTGCACCACTGCAGCCTGGGTGGCAGAGTGAGACTATGTCTCAAAAAAGCAAAACAAAACAAAACAAAACAAAAACCTAATACAAAGATTTCTTTTTTTTCCCCAAGACGGAGGACATTTATTTACTCTAGAGGGATGAGGACTCCCCTTCCTTTCAGACTTCCCCAGCCAGTCGTGCCTTGACTTTGTGTTTATGGACCTGTTGCCCACTCTCTGCACCTCCCCTTCCTAATAAAGGGGACTCAGTTTCTTGTCTCCTTCATGAATTCCTGTCTTGTCCTGGTCGGTTCTTCTCCTTGGCAGCACCCTTCCTTCTGGAGCTGCAGCACAGGTGGAGTGGAAGAAAAGAAAGCCTGTGACATTTGGCCACAAAAACTCTTAAATTATAAACTTGTGATTCTTTTCATACGTGTATCAGGAAGCACCCTAGTAAGATATACTGGCTTCCTAAGATATGCTCTGTCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGAGATTACAGGTGCCCGCCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGAGGGAGTTTCACCATGTTGGCCAGCTCGTCTCGAACTCCTGACCTCAGGTGATCCCCCCACCCCCAGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCACCTGGCCTATAGTGGCTCTTTATTCATGTAAAAATCAGACTTTTCCTATTCTGATCAGGAATGTTGACATATGCATACAGAATTCTATTGTTTCTATTTTCCTTCTTCAGTGCTGATGAGAGTGTTCCAAGCTGCTTCTTTTGGGCACAATTAGCGAAGTCCCTGAAAGAACCTGAGCCTGTAGTGTGGTTGGGACATTAGATGCATTTTGAAAACTTAAGTAAATGCTATAAATCTGAATGTTACTCTTTTTTAATCCCTTGAGATGAATACAGAACAGTTGCTCAGTGTCTTGAGTGAAAGGCATCTTTTTCTCTTTTGCAG
Seq C2 exon
GTAGTACAAGACTGGAAATTTGTAGCTCAAGTTCTTGACCGAATCTTCCTGTGGCTCTTTCTGATAGTGTCAGTAACAGGCTCGGTTCTGATTTTTACCCCTGCTTTGAAGATGTGGCTACATAGTTACCATTAGGAATTTAAAAGACATAAGACTAAATTACACCTTAGACCTGACATCTGGCTATCACACAGACAGAATCCAAATGCATGTGCTTGTTCTACGAACCCCGAATGCGTTGTCTTTGTGGAAATGGAACATCTCCTCATGGGAGAAACTCTGGTAAATGTGCTCATTTGTGGTTGCCATGAGAGTGAGCTGCTTTTAAAGAAAGTGGAGCCTCCTCAGACCCCTGCCTTGGCTTTCCCAGACATTCAGGGAGGGATCATAGGTCCAGGCTTGAGCTCACATGTGGCCAGAGTGCACAAAAAGCTGTTGCTACTTGGTGGAGGAACACCTCCTAGAAGCAGCAGGCCTCGGTGGTGGGGGAGGGGGGATTCACCTGGAATTAAGGAAGTCTCGGTGTCGAGCTATCTGTGTGGGCAGAGCCTGGATCTCCCACCCTGCACTGGCCTCCTTGGTGGTTTTGTCTGAGCTGCAAACTGGGGCCGTGTTATGCTTGTTAGCAATGGGCCAGGCAAATCTCAACAAGGGTTTGGGGATTACACTGGCAGGATAGCTGGCACTGCACACTTAACAATAACACAGATTCCAAGTTGCCTGGCCTACCGAAGCAGGTGTTATTCATGGTTTATTCCCAGCATGATAAGGCTTTCAGATGGTGAAACTGGAGCCCACTGTGAGCTGTGACTTCCTTTAAGGTCATGCATACCAAAATAACTCACAATAGAAACAAAGCCCTTTGCTACCAGAAGTGGATTCATTAATACCCATTATCTTTTCCTAGTAAACTAGTGTACAGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000147432:ENST00000289957:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0293118=Neur_chan_LBD=PD(55.1=38.3),PF0293211=Neur_chan_memb=PU(84.1=59.0)
A:
NA
C2:
PF0293211=Neur_chan_memb=PD(15.0=68.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains