HsaINT1022029 @ hg38
Intron Retention
Gene
ENSG00000168702 | LRP1B
Description
LDL receptor related protein 1B [Source:HGNC Symbol;Acc:HGNC:6693]
Coordinates
chr2:140234786-140238296:-
Coord C1 exon
chr2:140238152-140238296
Coord A exon
chr2:140234885-140238151
Coord C2 exon
chr2:140234786-140234884
Length
3267 bp
Sequences
Splice sites
5' ss Seq
AAGGTAGTA
5' ss Score
5.69
3' ss Seq
AATTTTCTGTTTATATACAGGCC
3' ss Score
7.93
Exon sequences
Seq C1 exon
GACAAAAACAATTAGAAGACAACCTATTATCAATGGAGGAATAAATGTAGAAATTGGCAATCCATCTTATAACATGTATGAGGTAGATCATGATCACAACGATGGAGGTCTTTTAGATCCTGGCTTTATGATAGACCCAACAAAG
Seq A exon
GTAGTATGTCTTAAGATAATGGGCAGTGAGCACTAACATTCTTGAGTCGCATCTCTGTTTTATGGTTCTGAATTTCACCAAGTTTTTCTGTTATCTGAAGTTAGAATAAGGGACTTTAGGATGTATTGAATGATATAGCCTCTTCTAAAGAGAAAGTACAATTATGGACTGCATTCACCTGAAGCTGAGTGTAACACATCTTAGAAAACACATATTTATTTGCTCAGTTCTTTTATAAACATGTTTTTATATGTTTTTTATTGAAAAATGATTCATTATCTAATTTTGTTTACATAAAGCAAACGAAAAACTCATTTAAAAATTGTTTTAGTATTGATATCACACAGCAAATTGTTTAGGTCTTCTTCAGGGGATAGATAGATATATAGATAGATAAAGGTCTATTATAAAGTAAAGCTACTGACTTTCAATGTTGAAATATATGCAAGGAGAAGACCAATACATGCACAGCTTCTAGAAATATGGCTGAAAAGTAGTTTGGTGAGACATTTTCTTTTCTACCCACTTCCTCCCAGTATTCCTTACAGTGTGGTTCTATGGGGTTTTGGTTTGGTAGGAACTGGATACTTACAAGATAGTTTTGTTTTCATCACTTCAGACATGGAATCCTTCTTTTAATGTTTTTTGTTTTAATTGATACATAATAAGTAGGAAATCAGTACATTGAAGAGATATCTGTACTTCCATGATTTTTACAGCATTATTCACAATAGCCAAGATATAGAATCAACCTAAGTGTGCATCAACAATGAATAAAGAAAATGCTATTCAGCCATAAAAAAGAAGGAAATCCTGTCATTTGAGGCAACATGGATAAAGCTGGATGATATTGTCATATATGAAATAATCCAGGCACAGAATGACAAATACCACATGATCTCACTCACATGTGAATCTATAGAAGTTAATATTGAAGTAGAGAGTAGAATAGTGGTTACTAGAGGGTGGAGAGGGGAGGAGGAAGGAAAATAGGTGTTGTTCAATGGGTACAAAGTCACAGTCAGATAAGAGGAATGGGTTTTGGTGTTCTGTTGCACAGTTAGGTGATGGTGGTTAACAATATTGTATTGTATATTTAAAAATAGCTAGAAAAGGATTTTTAATGTTCTCGCCACAAAAAAATAACTATGTATGAGGTGATAGATATGCTAAATACTTTGATTTTTTCTGCAATGTATACATGTATAAAAACATAACAAAACACAGTATCTCATAAATATGTATAATTCATGTAAAATAATGCTCTAATCAAATGTGTTGAGGTATTAGCAAATCTAGATACACAGCTTAGTGTAAAAATCTTGGTCAGTGTATTTTTTAAATATAAAAGAGTACAGTACTTTATTATCAAAATAAGTATGTTGTTTCCAATAATGTTTAAATGATGAGCCAGATAAGCTGTGTCCTTGGACTTCTTTGTAATTAAATCACTTTTGAGAAATATTTTTCTATCTGTCATAATATCCTTACTAGTTTAAAACATTTCATTGATACATATAGCCTGACAATCCACAGCCTTTTAAATTTAAAAATATTTGTTAGTTTTTATTACTATAAGCTGAGGTTGGCAACTTTTAAGGGAAATAGCTAAATGATACAATTATCCAGTTAAAGTTGTGAAGATTTACTTCAGTGAATTATCTGAATATTCTTTCTGATAATTTTAGAATATTTTTTCTCTAAATTAAGAGTATCAATTTAGTATTATGAAACAATTTTTCTTGGTTTATTCACTTATTTATTGAATAGTTATTTATTTTTCTGACTTACAAAAGTTACTTCATCAAAATGCACTTTTACATTGTAAATATCCAATGTGGCCAATCTACATTCAAATTATTTTGCAATCACAGTCATTGGTGTTCCTGAAGAATCTGAATAGGATCCCACATATTCAGTCTAGTTCTGAACCCATGATTAGGCTTTCTAAGCCTAAAATTGATGCTCAACTATTCACTTCTATGAAAATCAATCTTTTCACATGGATACATTGTGTACTATCAGAGAATATTATATTTTTCTAATTAGACATAATTTTATAGTTATTAAAATTCACTCCTACATCTGAAATTTTTCAAGGAAAAAGTCTTGGTAACCTTACATTTGATATTTTCTGCTTTAAAATATCACAGAAGTGGAGACATGATACATATTTTACACATTGCTATTGATAATCTATTATATCTATGAAGGAGAAAGACAAATAATAGAGTTCTGAAATTCTTTGCATTTTTCTTAGGAATAAAAATATAGTATTCATACATATAACAGACTAATGACGATATACTTTACACATTTTTCATATGAAGGAGGGTTATTTTTTCCTCATCATTTTTATTTCTAGTGATAGAATTAATCCAATTTTGTACACTTAAAGAGAATAGCTTTTTACACATTCAAAAATTTTCACATTTACTCTAGGAAGATAAAACTATGTTTCAGTGCCCCCAAATATATTTTAATGTACTTAGAACATAATACTCAAATATTTACCAATTGGATGACTGAATAACCAAAATTGCATCAAATATGACTTAGATGACTGATTCTATCTGGATCCTGATATTTGAATATAAATGTGAATTGTTGTCAAATGAGTAACTACAGAAAAAAACAGCTAGTTCTAATAGGTTTAGACAGTAGTGAGAAACAAAGGGCCATATTGAAGCAACCTTAATAATCATATGAATTTTATAGAGCATTCACTTTGTTACAAGCGTTTGATATATGCATGGTGCAATCAGTATAAATTACATTACATGTGAAGAAAAATTTTGTAGAACACTCATTTCTGTTATTCTCAAAGAGGGTAAAATTTCTAGTTCAATGGTATCTTATAATCAAAAGGATTGAAAGTACTTAATGCAGTTAATAAAATTGATTTGACTATGGGGGTAACCACAGAACAGTTTGAAGAGTTTAAAAGAGATAAATATGTACTAGTTTTATCTTCAAATTCATGCCAATTCTTACTTGGACTATTCTTTATATTTTCTGAATAAGACTTTTGTGAGAGAAATGTCTACCTATGAAGCAAAGATCCAATATTAATATTGGATCTTTAATAATATTAATATTGGATATTTTAAGTTGTTTTAAGTTGTTAAAGCTAACATGAACACACTGTAAATGGTGTAAGGCTAAAGGGTATTTTTATGTTATTTTTATGAATTAACATGATATGTATCGATGAAAAGTGATTCTATAATATTAGATCAGAAACTAAAATTTTCTGTTTATATACAG
Seq C2 exon
GCCAGGTACATAGGGGGAGGACCCAGTGCTTTCAAGCTTCCACACACAGCGCCGCCCATCTACCTAAACTCTGATTTGAAAGGACCACTAACTGCTGGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168702:ENST00000389484:89
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.027 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF151021=TMEM154=PD(11.8=18.4)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains