HsaINT1024126 @ hg38
Intron Retention
Gene
ENSG00000264424 | MYH4
Description
myosin heavy chain 4 [Source:HGNC Symbol;Acc:HGNC:7574]
Coordinates
chr17:10465442-10466416:-
Coord C1 exon
chr17:10466273-10466416
Coord A exon
chr17:10465599-10466272
Coord C2 exon
chr17:10465442-10465598
Length
674 bp
Sequences
Splice sites
5' ss Seq
TACGTGAGC
5' ss Score
4.3
3' ss Seq
AACCCCGTCCTTTCCCACAGACC
3' ss Score
11.5
Exon sequences
Seq C1 exon
ACTGTAACTGTGAAAGAAGACCAAGTCTTCTCCATGAACCCTCCCAAATATGACAAGATCGAGGACATGGCCATGATGACTCACCTGCATGAGCCTGCTGTGCTGTATAACCTCAAAGAGCGTTACGCAGCCTGGATGATCTAC
Seq A exon
GTGAGCACCCTTTCAACGCTATTTCTCACTCACTCCACATTCTACACATGTTAGCTAAAATAAATTAAGGGGTTTCAATACATTTGGCTATTGAACTGTTCTTTTATGACCAATTGTTTGGTTAATGTTGTAAACTCTGATATGTTTTAAAATGTACATGTGGAAAACCATTTACTTAACTGAATTAGTTGAAAAACTGGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCATCCCGGCTAAAACGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCGTAGTGGCGGGCACCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCGAGATCCCGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAGAAAAACTGAAGCATTTTGTGCAGCAGCAATGATGGAAGGAGGCAACAAATGAATGAAACTTTATGAGAACTAACACAGTACTTAGGTCCTGCTCTACTTGCCCTTAAACAGTATTTCCAAGATAGATAAACAAGGTGATTGCTGATCGAGGAACCCCGTCCTTTCCCACAG
Seq C2 exon
ACCTACTCGGGCCTCTTCTGTGTCACCGTCAACCCCTACAAGTGGCTGCCGGTGTACAACCCTGAGGTGGTGACAGCCTACCGAGGCAAAAAGCGCCAGGAGGCCCCACCCCATATCTTCTCCATCTCTGACAATGCCTATCAGTTCATGCTAACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000264424:ENST00000255381:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.019
Domain overlap (PFAM):
C1:
PF0273614=Myosin_N=PD(16.7=14.6),PF0006316=Myosin_head=PU(4.1=58.3)
A:
NA
C2:
PF0006316=Myosin_head=FE(7.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTGTAACTGTGAAAGAAGACCA
R:
AGCATGAACTGATAGGCATTGTCA
Band lengths:
296-970
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains