HsaINT1026506 @ hg38
Intron Retention
Gene
ENSG00000095464 | PDE6C
Description
phosphodiesterase 6C [Source:HGNC Symbol;Acc:HGNC:8787]
Coordinates
chr10:93662560-93663178:+
Coord C1 exon
chr10:93662560-93662643
Coord A exon
chr10:93662644-93663027
Coord C2 exon
chr10:93663028-93663178
Length
384 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGT
5' ss Score
11
3' ss Seq
TGACCTAAAATTCCTTTTAGGAG
3' ss Score
7.2
Exon sequences
Seq C1 exon
CCTATGATGGACAGAAACAAAAGAGATGAATTACCTAAACTTCAAGTTGGATTTATTGATTTTGTTTGTACTTTTGTATATAAG
Seq A exon
GTAAGTAAGCAAATTATTTGAATTAAATACATAAACATTTGGATGAGAAATTTTCTTTCAAACTGTCACCAAAATTTAGAAGTCACCCATACGGAAAGCCATTGGGGTATCACTGTTTCTCCAAAGCAGTTTGAGGTTTTACCCTAATCTCATTCAGGGCTGGAATAAAAGGAGGGAACTCAGATGTGAGCGAACTGAACACTTCCTTAGGCAGGCAGTAAAGACAGCACGTGTCTCTTTCCCAAACTTCATAGGCCCGTGGTTAAACTTATCCTAGCAGCTCTGAGTGCTGTAACAATTCCTTACAGCTCACTCTCTGCATATGAAAGATCCTGAAAATTAACTGTATGATTTATGTAGTTTCTGACCTAAAATTCCTTTTAG
Seq C2 exon
GAGTTCTCACGGTTTCACAAAGAAATCACACCTATGCTGAGTGGTCTTCAGAATAACAGAGTAGAATGGAAATCACTAGCTGATGAGTATGATGCAAAGATGAAGGTCATTGAAGAGGAGGCAAAAAAGCAAGAAGGAGGAGCCGAAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000095464:ENST00000371447:20
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.214 A=NA C2=0.275
Domain overlap (PFAM):
C1:
PF0023314=PDEase_I=FE(10.8=100)
A:
NA
C2:
PF0023314=PDEase_I=PD(7.6=37.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTATGATGGACAGAAACAAAAGAGA
R:
TTTTCGGCTCCTCCTTCTTGC
Band lengths:
233-617
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains