HsaINT1027382 @ hg38
Intron Retention
Gene
ENSG00000122194 | PLG
Description
plasminogen [Source:HGNC Symbol;Acc:HGNC:9071]
Coordinates
chr6:160711077-160713125:+
Coord C1 exon
chr6:160711077-160711191
Coord A exon
chr6:160711192-160712985
Coord C2 exon
chr6:160712986-160713125
Length
1794 bp
Sequences
Splice sites
5' ss Seq
TAGGTAAGA
5' ss Score
9.14
3' ss Seq
TTCTTTTCCATCCTCCCCAGATT
3' ss Score
10.39
Exon sequences
Seq C1 exon
TGTATCTCTCAGAGTGCAAGACTGGGAATGGAAAGAACTACAGAGGGACGATGTCCAAAACAAAAAATGGCATCACCTGTCAAAAATGGAGTTCCACTTCTCCCCACAGACCTAG
Seq A exon
GTAAGACATTCCCTTTCATCTTTGTGTTCATCTACTGTAAAGTTGTCCCTCTGTGTCTGTGAGGGATTGGTTCCAGGACCCCTGTGGCTACCAAAATCCATGCTTCTCAAGTCCCTTATATAAAATGGTGCAGTATTTGCATATAACCTACATACCTTCTCTTGTATAATCCCTAATATAATGTAAATGCTATTTAATCGTTGTTATACTGTATTGTTTTTATTTGTATTATGTTTTATTGTCATATTGTTATTTTCTGTCATCTTTTTCAAGTCTTTTCCATCCACAGTTGGTTGAATTTGTGGATCTGGAACCCATGGATACAGAGGGCCAACTGTATTTAGGATAATTTCATCACTTTTAATTCAAACCACAATATGTGAATAAGCAGATAGAAAGAATCTTTTTGATGTCGATGTTCAACTATTTTTGGCACCATAGTAGAACATGGTTGCTTTCTATTTTTTCTTGGATATGGAGGTTTCTTGAAGACCTAGAACATAGAAGAATGCCTAGTTTAAAAAAAATCAATGAAACTATGAGTTTTAGGCCAAATCTGAGAAAAGATCAAAGATGACTATGTTTGGGACTGAAGTAAGCATATCAGGTTAGAACTCTCATCACATGTTCGACTCAAATTGTGGAGCAAAAGAGTAAATAAGATATAAAAATGAAAATGAAGATACGTGAAATTCAAATGTTGCAACTTGCCTATTATTTATTTTAGTGCATTTTTTTGTACTTTTCCCAGTTTGGTGTTAGGTGGCATTAAGTTCTCAGTAATGACGCTTATCAAATAGGAACTTAGTGCTTGTTACTCACCTTTATCCATTCCCCCAACACTCAACAAATTGCCTTTGCTATATCCCTATGAGATGAGCAGATCAAATATTCCCCGTGAGTTAATGAAAACTGATTCAACCAAATGGCAAAGTCAGAGACTATCGGGGGCCATGGAGACACTCTGGGCCATTTTTATGAGGTAGTCTAGGCTCATCTTTATGAGGGAACTGAGGTCTCGGGGGGTGGGGGTTATCCCAAATAGGTTCACAGAAGAACCAGAAATAAAACCTGCCTTTCTAGACTGTAAGTCTTGTGATTTTCATCTAAATGGTTGTCTCTATACAGCAACTCATCTCTAGAACTGAAAATAAGCTTAAATCCCTCCTCCATCCCCAATAATTCAAGCTGCATTTCAGAGAAAACCAGGACTTTGGAATCAGACAGATCAACTTTGAATTCTTGATCTGCTTCTTCATAGCTATTTACACTTAGGCAAGTTTTGTTTTGTTTTGTTTTACGTTGCCACTCAGTTTTCTCATCTGTAAAATAGGGATAATAACACCTTCCTCAAATGGTTTTATTAGGACTAAAAGAGAGAATGTGTGGAAAGATGTTAGTGGAATTCCTGGCAGATAGTTCACATGGACAAAATGGTATTAACTACAAAAATTTTTACAGAGAAAACGGTAACTGACAAAAGCAGGTGTTTGGAATGAATTAAGACCATGGCAGCCTTTTGAGGCCTTTATATTTCTCCTGACTGTGCAATAAAAATATTTTGGCTCTCTAAGACTTGGCTGTCACAGTAGCAATGGTAATATTAGCTACTGTGCCAGAAGCAGCCTATCAATAGAGAAATTGAAAATCTGACCACACAAATGCTGCAGCACCCAGCTGAAATGCATTTGGATGACAATCTCAGATGGGAATCGAGAGCATCTCCTTCTGCCTTGCTAATAGCAAGCTGATTTTTAGAATATAGTCTAAGTGCTTCTTTTCCATCCTCCCCAG
Seq C2 exon
ATTCTCACCTGCTACACACCCCTCAGAGGGACTGGAGGAGAACTACTGCAGGAATCCAGACAACGATCCGCAGGGGCCCTGGTGCTATACTACTGATCCAGAAAAGAGATATGACTACTGCGACATTCTTGAGTGTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000122194:ENST00000308192:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.074 A=NA C2=0.285
Domain overlap (PFAM):
C1:
PF0002421=PAN_1=PD(1.3=2.6),PF0005113=Kringle=PU(41.8=84.6)
A:
NA
C2:
PF0005113=Kringle=PD(57.0=93.8)
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTATCTCTCAGAGTGCAAGACTGG
R:
CTTCACACTCAAGAATGTCGCA
Band lengths:
254-2048
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains