HsaINT1044248 @ hg38
Intron Retention
Gene
ENSG00000146426 | TIAM2
Description
T-cell lymphoma invasion and metastasis 2 [Source:HGNC Symbol;Acc:HGNC:11806]
Coordinates
chr6:155244658-155245731:+
Coord C1 exon
chr6:155244658-155244783
Coord A exon
chr6:155244784-155245622
Coord C2 exon
chr6:155245623-155245731
Length
839 bp
Sequences
Splice sites
5' ss Seq
AGAGTAAGT
5' ss Score
9.35
3' ss Seq
TTTCCCCTCTGCCCTTCTAGAAA
3' ss Score
11.58
Exon sequences
Seq C1 exon
ATGGAGTCACTTTTTGGAAGTTTGCCAGAGATGCTTGAGTTTCAGAAGGTGTTTCTGGAGACCCTGGAGGATGGGATTTCAGCATCATCTGACTTTAACACCCTAGAAACCCCCTCACAGTTTAGA
Seq A exon
GTAAGTATCTCAGATTTAGGCTTAAAGTAAAAATACGTGGCTATGGTACGTATTTCTCTCATGAGAATTCTCTCATGAGAAAGAATTTCTTGTCCTGTGACTATTGACTATTTATTGTCCTGTGACTATTTCCTTGCACCGTTTTCCTCTGTCAGGTGGTAAAGGAAGGCTGTATATATTTTTTTTTCCTGGCGCAGGTGCTTTTGGTAGTCAGAAGTCCAGCAGCACCTCCCGCCTGGTTGTTGACCACGTACGTGCTCTTTTCTCAGCTGCTGTGAAGGATATCCAAGGTGGTTGCTTCTGAAACCAGAGCTCCTACCCTGTGCCCAATCCTTCTTCCCCGTGGTCATGTGGATCTGGGATTAAGAGAATAGGTTTCTAATTGCTGGGCTCAAGCCCTCTCTTCTATGAAGCACCAGTGCTCCATAGCATCCGTGTAAGCCGCAGTGTGGCAGGAAGCCCCTCCAAGGGGACCTGGAACCATACAGACAGCATCACTCTCCCCAAGCAATGCAGAGTCGGCTTTATTAGTGAACCTCTCTCAGATTGTTTATATCCCACCTTGTCAGCTGTATTTTTGTAGAACTTTCTTTGTTTCTTGTCCTTGGATTGCACACTGTCAGTAGGCTCTGCCGCTGGAAACTTTGCAGTCAAGCTAGATACCTGCCAGGGGAGCGCCTGGGCTGTTCCCCACCTCCTGTGTGGATGGAGCAGGTTTGAACTTCTCCAAGGCATTAGTGCTATGGAATCTGACAGAAGCCATGGGGCCGTCAAATGCCATAAGCCAGCACGCATTGATTAAACCATGTCTGATTTGACTTTCCCCTCTGCCCTTCTAG
Seq C2 exon
AAATTACTGTTTTCCCTTGGAGGCTCTTTCCTTTATTACGCGGACCACTTTAAACTGTACAGTGGATTCTGTGCTAACCATATCAAAGTACAGAAGGTTCTGGAGCGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000146426:ENST00000318981:17
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.002 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0062115=RhoGEF=FE(21.6=100)
A:
NA
C2:
PF0062115=RhoGEF=FE(18.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGAGTCACTTTTTGGAAGTTTGCC
R:
ACCTTCTGTACTTTGATATGGTTAGC
Band lengths:
222-1061
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains