HsaINT1044250 @ hg38
Intron Retention
Gene
ENSG00000146426 | TIAM2
Description
T-cell lymphoma invasion and metastasis 2 [Source:HGNC Symbol;Acc:HGNC:11806]
Coordinates
chr6:155248000-155249969:+
Coord C1 exon
chr6:155248000-155248179
Coord A exon
chr6:155248180-155249850
Coord C2 exon
chr6:155249851-155249969
Length
1671 bp
Sequences
Splice sites
5' ss Seq
CGGGTGAGG
5' ss Score
8.48
3' ss Seq
TATGATTTCATATCTTGCAGAAG
3' ss Score
9.22
Exon sequences
Seq C1 exon
CTAAAACTGACAAAGCCTTCAAGGCTTTTCTGGACGCCCGGAACCCCACCAAGCAGCATTCCTCCACGCTGGAGTCCTACCTCATCAAGCCGGTTCAGAGAGTGCTCAAGTACCCGCTGCTGCTCAAGGAGCTGGTGTCCCTGACGGACCAGGAGAGCGAGGAGCACTACCACCTGACGG
Seq A exon
GTGAGGCGGCGGCGGCACCTCCGGGCGAGGGCCTGCACAGGGCGGCGAGGGGCTGCCAGCCGTGCCCTGGGCCTGACAGCTCACCTCTTCCCCGCCTAGTGGCACGTCCTAAGTCACTTTTCAGTTCTGCGATGGTTAATCTTAGGTTTCACGTGAATATGTGAAACTAGCTAGGCGTCTGGGCACTCCTTTAGAGCTTACAAAATACTTGGGTAGAAATGATCTCATCCGGGTAGCGCCATACTCCTCCTATGCAGGGATGATTCTGTCTTCACTCTCAAAATAAGTAAATTACCTCAGGTCACGTGGCTGTGAAACAGTGCCGCTGGAACTGAAAATCAGGCCTATTTTCCTACCACTTGGTTAAGTTTTGTGGGGTTCGCTGCCCGAGCTGCTGGTCAGATTTGTTGGGTGAGGCTCCACCTTGTGGAGATCTCTGAGCAGAGCTCGGCTTCAAAACCAAACTCCCAATGATGGGTTATGCTTTCAAGTCGCTACTGGTGTGTTACTGTTTGAACCTCTGAAATTACTGGCCTGAGACACAATTTATCAAAAACACAAAGCCTTGCAGTTTGATAGTAAATAGAGGATCCTTAAAGAGGGGCTTTATTTGGGTTGGAGATAGTGATTTGTTCATATGTTGAAACTAGGAGGTCCAATTAAACCATAGGTGATAAAATTTATGGGGAGAGAGAGGCTTATTAACACTTTAGTATTACTGAATAATAAATACTGAGAAGAGCGTAAATTAAACTGGCTTTTTTTCCATGACAAGCATACTTTGGTATCAAAATCAACAAGAGGAAAGCATTTTTGTATGACAGTTAACTTCTATAAGTAAATAATACAAATTATGTTCAGCATTCATACTATGTAAAAACTTCATTTTGTATTAAGATGATCTTTAGAAGGGTTTGATTTAAAAAACTTCCTTCCAAACTTCCCTCCAGTTAGAATTAAAATGCTGAATTGGGAGAAAAAAAAGTATAAAGAATACTGAATTTAGAAGTGACCTAAAATTTTGCTTTTTGGCTTTTATAAAATAATGTATCTCTCATATTCCCTCGCGGAAAGTTATGAACATATACCATATATAAATGCAAACAATTGTTCTGTCAGTCAGTCATGTACTGGGGTGTTTTTAAGTTCCATTTAAACCTAGATCCGGGTTCCCAGAAGGGCAAGCCAAACTCGAGAGCTGGTGCCCTAAGCCCAGTCAGGCTTGGGTTTGAAGCCTGGCTCCATTCTTGTGTTTTCCTCTCTGGAACTCTGGCAGAATATCCTGCACTCACTTTTCTCATCTGTAAAATGGGATGGTTTAGTCTTTGAGTTATTGCGGGCACTAAATGAGATGATTCACAGAAATCACCTGTCGTGATCCTTGCTAAGTAGAAAGTGCTCCAGAAATGTCAGTTGTTGTTATTAGTGATACTTTTCACTGATACTCTGTCTCATTTCAAAAAGAATTTGAAGTAGGAGATAATTTTGCTGTTCTTCATTCTAAGGGCTGGGCTACAGTGGGCTGTTGTGACTTATTCTGAATGTAATGCTCCTGCTAGTGGGTACTGGTCTGGAATCCTGAGTTGAATCTTGACTCCATTCATTATTACTGTTGGATAGAATCTAAAACAAATAACAGTTATGAAATAAATATGATTTCATATCTTGCAG
Seq C2 exon
AAGCACTAAAGGCAATGGAGAAAGTAGCGAGCCACATCAATGAGATGCAGAAGATCTATGAGGATTATGGGACCGTGTTTGACCAGCTAGTAGCTGAGCAGAGCGGAACAGAGAAGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000146426:ENST00000318981:19
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.011
Domain overlap (PFAM):
C1:
PF0062115=RhoGEF=FE(31.6=100)
A:
NA
C2:
PF0062115=RhoGEF=PD(7.4=35.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAAACTGACAAAGCCTTCAAGG
R:
CTTCTCTGTTCCGCTCTGCTC
Band lengths:
294-1965
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains