HsaINT1045694 @ hg38
Intron Retention
Gene
ENSG00000196230 | TUBB
Description
tubulin beta class I [Source:HGNC Symbol;Acc:HGNC:20778]
Coordinates
chr6:30720201-30722645:+
Coord C1 exon
chr6:30720201-30720563
Coord A exon
chr6:30720564-30722536
Coord C2 exon
chr6:30722537-30722645
Length
1973 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGA
5' ss Score
10.57
3' ss Seq
TCGTTGCTCCCCCTCGGCAGTTC
3' ss Score
7.37
Exon sequences
Seq C1 exon
GTACATGACCGGCATCGACTAATCAGGGCCAGGCTCGATGAGGCTTTGTCTCCCTACCGCGCGCGGGGCCGATTCTCCCGCCTCCCAGCCCCGGCGCACGCGCGCCCCGCCCAGCCTGCTTTCCCTCCGCGCCCTCCCCTCTCCTTTCTCCCTCTCAGAACCTTCCTGCCGTCGCGTTTGCACCTCGCTGCTCCAGCCTCTGGGGCGCATTCCAACCTTCCAGCCTGCGACCTGCGGAGAAAAAAAATTACTTATTTTCTTGCCCCATACATACCTTGAGGCGAGCAAAAAAATTAAATTTTAACCATGAGGGAAATCGTGCACATCCAGGCTGGTCAGTGTGGCAACCAGATCGGTGCCAAG
Seq A exon
GTAAGAATTTTACACCTCTTTTATTTCTTTTTACAAGGAAAAATCCAGGTAAGTTATGAAAAAATGGTTGTGGGGCATTTGCACCCGCTATCCTTAATCAAGATTTGCCCCTCTCAAGTTTGTTACATTTATATATATAACAATTGTAGCTAGCATTTGCCTTTGGAAAGCTGGGAATCATTTTTCTTGGCAGGCACATTTTGGAGAAACTAGTAAAAGGGCTCTTCGGGTTTGGGGGCGGGAAGACCGAGGACTTATAAGATGTTACTTAAAAGGGCTTCTAACGGTCCGAGAACCGGGCAGGGAGAGAGATGCGGAAACGGTCGCAGACAAAGCGGGGCGAGGTTTTGCCCATGTGCATCCCGCCCAACCCCCCTGCGGGGTACTTAGGGCCAAACCGGAGCGGGAAGGGGTGAGGCCATCGGGCGGCTGCAGAGAGCTCCAGCGCAAGGGTGGGGGGCGATGCGCCAGGGTGGGCTGCGCTGGGCGCTACCTTTCACAAAAGACCAGGGACCCCAACGCGCCCGCGACCCCAGAGGGCCGGTCCTGTATTTGTTCCTGGGTGGAAGGAGAATAAGAACGGGATTAATTTTACTTGCTTTCATGGCCCCTAAGAGAGACTTTTTTAGGGCGTGAACAGATATGTCGAGAAAATGGGGGTGTGTGGTTTTCTTTAATGAGTCCCTCAGGACTTAATGGGAGAGAAAGAATCCTTTAAATCAAGGGGTAGAAATGTAGCGAAGGAATAAAAATTCCGAGGCCAAGGGGGATTTTTTTTTTTTGCGCGCGGTTACAGTGTAGCGGGGGAGGGGCGGGAGGAAGTGCGGCTGCTACGTTGTAGCAGAAGGGCGGGGCCCTGCGGGGCGGGGCCGGGGCGCCGTGGGCGCGCGGGGACAATGCGGCGTTGCCCGCCGGCAGGGGCGCGCTACCTTGGGCCCCGCCCCTCGCGCGCGGAATTTTTGTCCCTGGCCCCGCCCACGCGCGAAGTCTTTTGTCGGCGGCTCGACCTGCGCGTGCGCCGCAGTCACGTGGAGGGCGGGGGGGGTGGTCGACTGCGGCGGCAGCTCTTTCCTCAGACCCCCAGCCTTTTGTGCGCCGCGCGGTGGGGCGGTGCCCAGCTTGGGGGAAGGAGAGCGGCGCTTATCGAAGTGTGGTCGACCTCCATCCGCCCACCGAGCACTTGGGACCCGCTGCACATATCCAGAGCAGGGAAAGCTGTGGCTTTCTCGGGGGAGCGAGTGTCTAGGGGAAGGGTGTGGCAGGCCCACGGGATGCCATGCCCTAGAACAACGGCCTGAGCGCTTGTGGAATTAAAATGGGAGATGTGGGGCCGAGGTGGGCGAATTGGGATCCCTCCAGGTCAGGGGTTCGAGACCATCCTGGGCAACAAAGCGAGACCCTCCCCCATGCCACGTTTCTACAAAAAATAAAAGTAAAAAATTAGCTGGGCGTGGTGGCGCGCGTCTGTGGTCCCAGCTACTCGAGAGGCTGAGATGGGAGGATCGGTTGAGCCTGGGAGTTCCACGCTGTAGTCATCCGTGATTGCACCACTGCACTGCAGGCTGGGCAACAGGAAGACCCTGTCTTAAAAATTAGAAGAAGCTGGGCGCGGTGGCTCACCCTTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCGGATCACGAGGTCAAGAGATCTAGACCATCCTGGCCAACATGGTGAAACCCGTCTCTACTAAAAATACAAAAAGTAGCTGGGCGTGTTGGTGCGCGCCTATAGTCCCAGCTACTCCGGGGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAAGCAGAGGTTGCAGTGAGCCGAGATAGCGCCACTGCACTCCAGCCTGGTGACAGAGCGAGACTCCGTCTCAAAAAAAATTAAGAAAAAGATGAAATAAAATGGTAGTTGGGGACATAGTTGGCTGGGACTTGACCTGTTGTGGTCTCGTTGCTCCCCCTCGGCAG
Seq C2 exon
TTCTGGGAGGTGATCAGTGATGAACATGGCATCGACCCCACCGGCACCTACCACGGGGACAGCGACCTGCAGCTGGACCGCATCTCTGTGTACTACAATGAAGCCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000196230:ENST00000327892:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.122
Domain overlap (PFAM):
C1:
PF0009120=Tubulin=PU(7.2=84.2)
A:
NA
C2:
PF0009120=Tubulin=FE(16.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTCGATGAGGCTTTGTCTCC
R:
TCATCACTGATCACCTCCCAGA
Band lengths:
354-2327
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains