HsaINT1048181 @ hg38
Intron Retention
Gene
ENSG00000221988 | PPT2
Description
palmitoyl-protein thioesterase 2 [Source:HGNC Symbol;Acc:HGNC:9326]
Coordinates
chr6:32155871-32157720:+
Coord C1 exon
chr6:32155871-32155978
Coord A exon
chr6:32155979-32157636
Coord C2 exon
chr6:32157637-32157720
Length
1658 bp
Sequences
Splice sites
5' ss Seq
ATGGTGAGT
5' ss Score
10.13
3' ss Seq
TAACTGCTGTTTGTACCCAGATC
3' ss Score
7.94
Exon sequences
Seq C1 exon
ACACGGACTACTTGAAGTGGCTGTTCCCCACCTCCATGCGGTCTAACCTCTATCGGATCTGCTATAGCCCCTGGGGCCAGGAATTCTCCATCTGCAACTACTGGCATG
Seq A exon
GTGAGTGGGGATGCTGAACTGGGGCTTCCATGGATCAGGTCAGTTGCTTCCACCTCTGCTACAACCAATAGCAGTGATGACAATAAAGATAACTTACATTTATTGAGTTATTTGAACAGGCTCTGTTCAGAATTTTTTTTTTTTTTGAGACGGAGTCTTGTTCTGTTGCCCAGGCTGGAGTGCAGTGCACCATCTTGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGTGATCCTCCTGCCTCAGTCCCCCTAGTAGCTGGGATTACAGGCAGGCGCCATCATGCCCGGCTAAGTTTTGTATTTTAAGTAGAGATGGAGTTTCGCCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACTCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAACCATTGCACCTGGCCCAGAATGTTTTAAGTGTGTCACCTTATTGCCTTAGAAGGTTTAGTCTGATGTGGGAGTCAGCAAACCTTGTCTATAAAGGGCCAGAGAGTAAATATTTTTGACTTTGTAGGACATATAGTCTGTTTCACAACTCCTCAATTCTGCTGTTGTAGTGTGAAAGCAGCCATGTACCATATGTGAATGAATGTGCCTGTGTTCCAGTAAAACTTCATTTACAAAAACAAGTAGCAGGCTGGATTTGGTCCTTTGGTCACAGTTTGCCAACCTCTAGACCAGACCATGGGGCCAGAATACTTGGGTTTGAATCTTGACCCTATTGGGTGCCTTTGGGCAAGTTACTTAACCATTCTGTTACTCAGTTTTCCTTATCTGTAAAATATTATAGCATGTACTTCACCAGGTGGTTGTAAGGATTAAATAAATAAATGAATGCAATGTACTTTGAATAGTACCTGGCTCATATAGTAGATACTAGATAGAAGTACTTGCTATTGCCAGGTGTGGTGGCTCACACCTGTAATCCCAATATCTTGGCAGGGGGAGGTGGGCGCATCACCTGAGGTCGGGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAAAAATTTAGCTGAATGTGGGCACACGCTTGTAATCCCAGCTACTCAGGATGCTGAGTCAGGAGAATTGCTTGAACCCGGGAGGCAGATGTTGCAGTGAGCGGAGATCCTGCCACTGCACTTCAGCCTGGGTGACGGAGTGAGATTTCATCTAAAAAAAAAAAAGTACTTGTTACTATGTTTACGGTTGTTATCACTACTATTATTATTTTGAGATGGAGTCTCACTGTGTCTCCCAGGATGGAGTGCAGTGGTGCAGTCTCGGCTCACTGTAACCTCCACCTCCTGGGTTCAAGTGATTCCAGCGCCCCGAGTAACTGGGATTACAGGCATGCACCACCACGCCTGGCTAACTTTTGTATTTTTAGTAGAGACAGGGTTTCGCCATGTTAGCCAGGCTGGTCTCAAACTCCCGACTTCAAGTGATCCACCTGCCTCTACCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGCACCTGGCCTACATTATCACTACTATTTTATTACTATCCACCTTGACTATTGCTGCAGCTTCCTTATTGGGCTTTTCACCACCAGTCTTGCCTCCCTTTTCTGCTTCTTTTTCTAACTGCTGTTTGTACCCAG
Seq C2 exon
ATCCCCACCACGATGACTTGTACCTCAATGCCAGCAGCTTCCTGGCCCTGATCAATGGGGAAAGAGACCATCCCAATGCCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000221988:ENST00000361568:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF126972=Abhydrolase_6=PD(21.9=81.1)
A:
NA
C2:
PF0208910=Palm_thioest=FE(10.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACACGGACTACTTGAAGTGGC
R:
CTGTGGCATTGGGATGGTCTC
Band lengths:
192-1850
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains