MmuEX0022283 @ mm10
Exon Skipping
Gene
ENSMUSG00000024459 | H2-M5
Description
histocompatibility 2, M region locus 5 [Source:MGI Symbol;Acc:MGI:95917]
Coordinates
chr17:36987655-36989204:-
Coord C1 exon
chr17:36988935-36989204
Coord A exon
chr17:36988505-36988780
Coord C2 exon
chr17:36987655-36987930
Length
276 bp
Sequences
Splice sites
3' ss Seq
TACGACCGGGGCGGGGCCAGGCT
3' ss Score
-1.05
5' ss Seq
CAGGTATAT
5' ss Score
7.88
Exon sequences
Seq C1 exon
GCATCCATTCCTTGCAGTTTTTTGCCACCACCATGACCCAGCCTGGTTTGAGGGAGCATTCCTTCATCTTTGTCGTCTTCGTGGACGACACACAGTTCCTGTGCTACAACAATAAGGGGAAAAATCAGAGAATGGAGCCACGCGCTCTGTGGGTGAAGCAGATGGGGCCAGAGTATTGGGAACAGCAGACCAGGACTGTCAAGGTCATTGAGAAGATTGCCCTAGTGAATTTGCAGGAGGCCATGGACATCTACAACCACAGCAAGGATG
Seq A exon
GCTCTCACGTCTTTCAGTGTGTGTATGGCTGCGAAGTGGGGCCAGATGGACTCTTCCTCCGTGGGCATGAGAAGCACGCATACGACGGCCGCGATTACCTCACCCTAAGCCCGGACCTGCACTCCTGGGTCGCAGGCGACACAGCTGCGCAGATCACGCTGCGCAGGTGGGAGAAGTCTGGTGTCTCTGAGCAAAGGCAATCCTTCTTGAAGGGCGAGTGTGTGGAGTCGCTCCGCACATACCTGGAGATAGGGAAGGAGACTCTGCTAAGAACAG
Seq C2 exon
ATCCTCCCAAGGCACATGTGACCCATCACCCCAGACCTGAAGGTGAAGTCACCCTGAGGTGCTGGGCCCTGGGCTTCTACCCTGCTAACATCATCCTGACCTGGCAGTGGGATGAGGAAGACCTGACTCAGGACATGGACCTCATTGAGACCAGACCTGCAGGGGATGGGACCTTCCAGAAGTGGGCATCTGTGGTGGTACCTTCTGGAGAGGAACAGAGATACACATGTCATGTGCAACATGAGGGGCTAACCCAGCCCCTTGTTCTAAAATGGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000024459_MULTIEX1-1/2=C1-C2
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.032 A=0.003 C2=0.136
Domain overlap (PFAM):
C1:
PF0012913=MHC_I=PU(80.0=97.3)
A:
PF0012913=MHC_I=PD(49.2=94.6)
C2:
PF0012913=MHC_I=PD(15.6=7.6),PF0765410=C1-set=WD(100=92.4)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCCAGAGTATTGGGAACAGC
R:
AGATGCCCACTTCTGGAAGGT
Band lengths:
296-572
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types