Special

MmuEX0026153 @ mm9

Exon Skipping

Gene
ENSMUSG00000038366 | Lasp1
Description
LIM and SH3 protein 1 [Source:MGI Symbol;Acc:MGI:109656]
Coordinates
chr11:97660961-97668233:+
Coord C1 exon
chr11:97660961-97661288
Coord A exon
chr11:97662277-97662428
Coord C2 exon
chr11:97668139-97668233
Length
152 bp
Sequences
Splice sites
3' ss Seq
TCTTGTGACCCCCTCTGCAGGGA
3' ss Score
8.95
5' ss Seq
AGGGTTAGT
5' ss Score
5.02
Exon sequences
Seq C1 exon
GGGAAGGAGGGCGGAGGCGGAGGCCAGTTCCCCAGTTCCAGTCGCCGTCGCCTGCACAGTTGCAGCCGCCGCCTCCCACCAGCTCGCCCAAGGAAAAGGGAACGCGCGCGAATACGGGCGTCCCCGCCCCAGTCTTTCCCCGGAACCATGAACCCTAACTGTGCCCGGTGCGGCAAGATCGTGTACCCCACGGAGAAGGTGAACTGTCTGGATAAGGTGAGCTCGGGTACCGGGCGCTGCGAGCTAGCCAGTGCTAGTGCAGCTCTCCATCAGGGGAGGAAAGAGGGGCCGGGTCTTTGCGGGCTCTTCCCTGCGCTCCCCAGAGCAG
Seq A exon
GGAAGCCTTTTGGCTCCTCATAGATACGTTGTACCTGGCTCTCCAAGCTGGATCTCATTCTCCACGTTTATGGCTGAACTGGACAGAAGCAGGCGCCTCAATGAGGCGATCTAGTTTTGTTGGAAAAGGATACTTTGTTTCTCCGGGCTAGG
Seq C2 exon
TACTGGCATAAAGCATGCTTTCACTGCGAGACCTGCAAGATGACCCTGAACATGAAGAACTACAAGGGTTATGAGAAGAAGCCTTACTGCAATGC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000038366_CASSETTE1
Average complexity
S
Mappability confidence:
50%=100=100%
Protein Impact





	

	
5' UTR





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.035
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF062218=zf-C2HC5=WD(100=100.0),PF0041217=LIM=PU(75.0=78.3)

							
A:
PF062218=zf-C2HC5=PD(27.3=23.7)

							
C2:
PF0041217=LIM=FE(54.4=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000116102f5640A





     
                   









    
Main Skipping Isoform:
ENSMUSP00000042123





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000116102
  



Associated events






Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
chr17:37027623-37027884 
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr19:40092309-40092524 
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CAGTCTTTCCCCGGAACCATG

				
R: 
TCAGGGTCATCTTGCAGGTCT

				
Band lengths: 
248-400

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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