MmuEX0026901 @ mm10
Exon Skipping
Gene
ENSMUSG00000030201 | Lrp6
Description
low density lipoprotein receptor-related protein 6 [Source:MGI Symbol;Acc:MGI:1298218]
Coordinates
chr6:134520396-134566913:-
Coord C1 exon
chr6:134566643-134566913
Coord A exon
chr6:134541652-134542045
Coord C2 exon
chr6:134520396-134520593
Length
394 bp
Sequences
Splice sites
3' ss Seq
TATTTTTCTTTTTGTTTCAGCGG
3' ss Score
10.19
5' ss Seq
TGGGTAAGT
5' ss Score
10.24
Exon sequences
Seq C1 exon
GGCGGCGGCATGGGGGCAGGCGCTGGCGTCGCGCGAGCCCGGGCCGGAGCGGCGCGCTAGAGCCCTGACGTGCGCCCTTTTCTTTCTTCTCGCGGCCGCGGAAAGCATGAGCGTGCAGACCCGCCGCTGCGGCGGCCGCCCCGGCTCCTCGCCCGCGCGTCCCCTGGCCGCCGGGCGCCGGTGAGGGCCGCGAGCGCGCGCGGTGGTGGGGGGAAGATGGGGGCCGTGCTGAGGAGCCTCCTGGCCTGCAGCTTCTGCGTGCTGCTGAGAG
Seq A exon
CGGCCCCTTTGTTGCTTTATGCAAACAGACGGGACTTGAGATTGGTTGATGCTACAAATGGCAAAGAGAATGCAACGATTGTAGTTGGAGGCTTGGAGGATGCAGCTGCGGTGGACTTTGTGTTTGGTCATGGCTTGATATACTGGAGTGATGTCAGCGAAGAAGCCATTAAACGAACAGAATTTAACAAAACTGAAAGTGTACAGAATGTTGTTGTTTCTGGATTATTGTCCCCGGATGGGCTGGCATGTGATTGGCTTGGAGAAAAATTGTACTGGACAGATTCTGAAACTAATCGTATTGAAGTTTCTAATTTAGATGGATCTTTACGAAAAGTTTTATTTTGGCAAGAGTTGGATCAACCCAGAGCTATTGCCTTAGATCCATCAAGTGG
Seq C2 exon
GTTCATGTACTGGACAGACTGGGGAGAAGTGCCAAAGATAGAACGTGCTGGGATGGATGGCTCAAGTCGCTTCGTTATAATAAACACAGAGATTTACTGGCCAAACGGACTGACTCTGGACTATCAGGAGCGGAAGCTTTACTGGGCCGATGCAAAACTTAATTTCATCCATAAATCAAACCTGGATGGAACAAACCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030201-'0-3,'0-1,5-3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0005812=Ldl_recept_b=WD(100=31.8),PF0005812=Ldl_recept_b=WD(100=31.1),PF0005812=Ldl_recept_b=PU(0.1=0.0)
C2:
PF0005812=Ldl_recept_b=WD(100=62.7),PF0005812=Ldl_recept_b=PU(53.7=32.8)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGTGCGCCCTTTTCTTTCTTC
R:
CATCGGCCCAGTAAAGCTTCC
Band lengths:
355-749
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types