Special

MmuEX0045257 @ mm9

Exon Skipping

Gene
ENSMUSG00000026718 | Stam
Description
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 [Source:MGI Symbol;Acc:MGI:1329014]
Coordinates
chr2:13995727-14024112:+
Coord C1 exon
chr2:13995727-13995963
Coord A exon
chr2:13996054-13996174
Coord C2 exon
chr2:14024028-14024112
Length
121 bp
Sequences
Splice sites
3' ss Seq
CGTTCGTTCATTCTGGATTCCCG
3' ss Score
-10.77
5' ss Seq
TTGGTAAGG
5' ss Score
8.92
Exon sequences
Seq C1 exon
TGTTCCGCTTCTCGGCTGTTGCCGCCGCCGCCGCCTCTGTTGCTGGGGTGGGTGAGAGGAGGGGCTGAGAGGGACCCTGCACTGGCAGGCAGGCGCCCTTGCTGTGTTTGTACCTGAGGGGCCTCCTTTCTCCGTCACCCCTAGAGTGCCGCGGGGTCGAGGGGCAGTCCCCGGGGACACCTCGGCACGCAGCGGACATGCCTCTCTTTGCCACCAACCCCTTCGACCAGGATGTTG
Seq A exon
CCGAGGCCGAGCCCACGTTCTTCTCTCCCGGGGCCCCTTCGTTCAGAGTTGGGAGAGGGTTGAGCGCTTGGCGCATCCTCTTTGGAAGAAATGGGACTTAGAACCTCTCTAATGGGCCTTG
Seq C2 exon
AGAAAGCAACTAGTGAGTTGAATACTGCTGAGGACTGGGGCCTCATCTTGGATATTTGTGATAAGGTTGGCCAATCTCGCACAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026718-'0-2,'0-1,1-2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (No Ref, Alt. ATG)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.045 C2=0.023
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0079014=VHS=PU(6.7=64.3),PF136461=HEAT_2=PU(0.9=7.1)

							
A:
PF0079014=VHS=PU(5.3=63.6),PF136461=HEAT_2=PU(0.8=9.1)

							
C2:
PF0079014=VHS=FE(20.7=100),PF136461=HEAT_2=FE(25.2=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000121228





     
                   









    
Main Skipping Isoform:
ENSMUSP00000100025





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000028050
  



Associated events






Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
chr10:17686460-17686590 
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr13:32390438-32390556 
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CTGAGAGGGACCCTGCACTG

				
R: 
GTGCGAGATTGGCCAACCTTA

				
Band lengths: 
255-376

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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