Special

MmuEX0046412 @ mm9

Exon Skipping

Gene
ENSMUSG00000029192 | Tbc1d14
Description
TBC1 domain family, member 14 [Source:MGI Symbol;Acc:MGI:1098708]
Coordinates
chr5:36837667-36850355:-
Coord C1 exon
chr5:36850227-36850355
Coord A exon
chr5:36847674-36847783
Coord C2 exon
chr5:36837667-36837925
Length
110 bp
Sequences
Splice sites
3' ss Seq
TGTTTAACATTGTCTCCTAGATG
3' ss Score
8.03
5' ss Seq
TTGGTAAGA
5' ss Score
8.85
Exon sequences
Seq C1 exon
GTTCAGGGCATGTCCTTTATAGCTGCAGTGTTGATCTTGAACCTCGATACTGCAGATGCCTTTATTGCTTTTTCTAATCTTTTGAATAAACCCTGTCAAATGGCGTTTTTCCGAGTGGACCATGGCCTT
Seq A exon
ATGTTGACTTACTTTGCTGCATTTGAGGTATTCTTTGAAGAAAACTTGCCGAAATTGTTTGCGCATTTCAAGAAAAACAACTTAACTGCAGATATCTACCTAATCGATTG
Seq C2 exon
GATTTTCACCTTGTACAGTAAGTCCCTGCCCTTGGACTTGGCCTGCCGCATCTGGGACGTATTCTGTCGAGATGGAGAGGAATTTCTCTTCCGCACAGCTCTGGGCATCCTGAAGCTTTTTGAAGATATCCTGACCAGGATGGACTTCATCCACAGTGCCCAGTTTCTGACCAGGCTGCCTGAGGACCTGCCCGCAGATGAAGTGTTTGCAGCTATCTCCACAGTCCAGATGCAAAGCCGGAACAAGAAATGGGCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000029192_MULTIEX1-10/11=9-C2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0056613=RabGAP-TBC=FE(18.4=100)

							
A:
PF0056613=RabGAP-TBC=PD(1.2=3.6),PF0056613=RabGAP-TBC=FE(33.8=100)

							
C2:
PF0056613=RabGAP-TBC=PD(19.7=51.7)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000116519





     
                   









    
Main Skipping Isoform:
ENSMUSP00000134405





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000031094, ENSMUSP00000084830, ENSMUSP00000098830, ENSMUSP00000114508, ENSMUSP00000115467, ENSMUSP00000115926, ENSMUSP00000117414, ENSMUSP00000119347, ENSMUSP00000121516, ENSMUSP00000121816, ENSMUSP00000131876
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr4:7014448-7014557 
HIGH PSI
HsaEX6083490
(TBC1D14)
Human
(hg19)
chr4:7016175-7016284 
HIGH PSI
HsaEX6083490
(TBC1D14)
Rat
(rn6)
chr14:79429107-79429216 
HIGH PSI
RnoEX0088803
(Tbc1d14)
Cow
(bosTau6)
chr6:118290890-118290999 
HIGH PSI
BtaEX0035699
(TBC1D14)
Chicken
(galGal4)
chr4:79494305-79494414 
ALTERNATIVE
GgaEX0022809
(TBC1D14)
Chicken
(galGal3)
chr4:82887594-82887703 
ALTERNATIVE
GgaEX0022809
(TBC1D14)
Zebrafish
(danRer10)
chr7:39427657-39427766 
HIGH PSI
DreEX6006584
(tbc1d14)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
ACCTCGATACTGCAGATGCCT

				
R: 
CTGGGCACTGTGGATGAAGTC

				
Band lengths: 
252-362

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"