MmuEX1010958 @ mm10
Exon Skipping
Gene
ENSMUSG00000041798 | Gck
Description
glucokinase [Source:MGI Symbol;Acc:MGI:1270854]
Coordinates
chr11:5903100-5904544:-
Coord C1 exon
chr11:5904361-5904544
Coord A exon
chr11:5903560-5903744
Coord C2 exon
chr11:5903100-5903255
Length
185 bp
Sequences
Splice sites
3' ss Seq
TTTTATGAGTTTCCTCACAGACC
3' ss Score
5.73
5' ss Seq
CCAGTAAGC
5' ss Score
5.34
Exon sequences
Seq C1 exon
GCACCGGCTGCAACGCCTGCTACATGGAGGAGATGCAGAATGTGGAGCTGGTGGAAGGCGATGAGGGGCGCATGTGTGTCAACACAGAGTGGGGCGCCTTCGGGAACTCCGGTGAGCTGGACGAGTTCCTCCTGGAGTACGACCGGATGGTGGATGAGAGCTCAGTGAACCCCGGTCAGCAGCT
Seq A exon
ACCCTCACGGGCCTCTGTTAGGTCATTTAATATCTGCTGGATTTCAAGACGAAAATATGGAGCCTCACACATTAGACAAAAATATACCAGGCTGCATGTGCCATGCCGGGCACCAACCCTGTGAGCCACTGAGAATGGTTGTCACTAAATTCCAGGGTGTGGGCTTCACACAAGGCCTGTCACCA
Seq C2 exon
GTACGAAAAGATCATTGGCGGAAAGTACATGGGCGAGCTGGTACGACTTGTGCTGCTCAAGCTGGTAGAGGAGAATCTTCTGTTCCACGGAGAGGCCTCAGAGCAGCTGCGCACACGTGGTGCTTTTGAGACCCGTTTTGTGTCGCAGGTGGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000041798-'19-14,'19-13,20-14
Average complexity
S
Mappability confidence:
88%=100=75%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.020 A=0.024 C2=0.000
Domain overlap (PFAM):
C1:
PF0372711=Hexokinase_2=FE(25.4=100)
A:
PF0372711=Hexokinase_2=PD(5.4=9.5)
C2:
PF0372711=Hexokinase_2=FE(21.7=100)
Main Inclusion Isoform:
ENSMUST00000102920fB10428
Other Inclusion Isoforms:
NA
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGCAGAATGTGGAGCTGGTG
R:
GCCTCTCCGTGGAACAGAAGA
Band lengths:
248-433
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types