MmuEX1018543 @ mm10
Exon Skipping
Gene
ENSMUSG00000044220 | Nkx2-3
Description
NK2 homeobox 3 [Source:MGI Symbol;Acc:MGI:97348]
Coordinates
chr19:43612325-43615892:+
Coord C1 exon
chr19:43612325-43612849
Coord A exon
chr19:43613261-43613476
Coord C2 exon
chr19:43614306-43615892
Length
216 bp
Sequences
Splice sites
3' ss Seq
TGTCTTTCTTCTAACGTGAGGTG
3' ss Score
2.78
5' ss Seq
GAGGTGAAG
5' ss Score
4.41
Exon sequences
Seq C1 exon
CCAATGGAGGGGATTTAGACTGGACCGCGTCTGTCAAAAGCTCGACTCCGCACCACCGCGGAGTCCAGAAGAAGAGCTGGAGCCACCGCACTCCCTCCCCGCCCCCGCCGGGATTTATTGAGTATTTGGACTGGACAATTAAGTGGCCCTGATGATGTTACCAAGCCCGGTCACCTCCACCCCTTTCTCAGTCAAAGACATTTTGAATCTGGAGCAGCAGCGGCACTTCCACGGAGCTCACTTGCAGGCGGAATTGGAGCAGCACTTCCACTCGGCACCCTGCATGCTGGCCACGGCTGAAGGGACGCAGTTTTCCGATGCAGGGGAGGAGGACGAGGAAGAAGAGGGAGAGAAACTGTCCTATTTGAACTCACTAGCTGCTGCCGAGGGCCATGGAGATTCGGGTCTCTGTCCTCAGAGCTATGTCCATACAGTTCTCCGAGACGCTTGCAGCGGGCCCAAGGAACAAGAAGAGGAGGTTGTGAGCGAACGGAGCCAAA
Seq A exon
GTGAATTCAGCGAGGCCAGGGCAGTCACCCCGGCTGTCCCGAAAAGGCAGTGCAAGAATGTTGTGTTTGGGCCATCCTTTCGGGCAAGACTTTGAGAGACACCAGCTTACTTCGGAGCTTGCAGTTCTTACGTTCGAACTGCAAGGAGGAGAGGTGGTGGCCAATGTGTGGGAGCTCGATCCATATCAGATGACGGCAGCAAGTCACACCCAGGAG
Seq C2 exon
AAAGCTGTCAGTTGAAGAAGTCTCTGGAAGCGGCGGGAGACTGTAAGACGAGCGAGGACGGCGAGAGGCCGAAGCCGCGGAGCCGCCGGAAGCCCCGGGTGCTCTTCTCGCAAGCTCAGGTCTTTGAGCTGGAGCGCAGGTTCAAGCAGCAGCGGTACCTGTCGGCGCCCGAGCGCGAGCATCTCGCCAGCAGCCTGAAGCTCACGTCCACGCAGGTGAAAATCTGGTTCCAGAATCGCAGGTACAAGTGCAAGAGACAGCGGCAGGATAAGTCCCTGGAGCTGGGGACGCACGCGCCGCCGCCGCCACCCCGCCGCGTGGCAGTGCCGGTGCTCGTGCGGGACGGCAAGCCGTGCGTCACGCCCAGCGCACAAACCTACGGCTCGCCCTACGGCGTGGGCGCCGGCGCCTACTCCTACAACAGCTTCCCCGCCTACGGCTACGGGAACTCGGCCGCCGCAGCCGCTGCAGCCGCCGCAGCCGCAGCAGCAGCGGCGGCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000044220-'0-1,'0-0,1-1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.530 A=0.323 C2=0.211
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0004624=Homeobox=WD(100=23.1)
Main Inclusion Isoform:
ENSMUST00000057178fB13630
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGAAGAGGAGGTTGTGAGCGA
R:
ACTTATCCTGCCGCTGTCTCT
Band lengths:
305-521
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types