MmuEX6056613 @ mm10
Exon Skipping
Gene
ENSMUSG00000023034 | Nr4a1
Description
nuclear receptor subfamily 4, group A, member 1 [Source:MGI Symbol;Acc:MGI:1352454]
Coordinates
chr15:101266846-101271865:+
Coord C1 exon
chr15:101266846-101266971
Coord A exon
chr15:101270083-101270969
Coord C2 exon
chr15:101271736-101271865
Length
887 bp
Sequences
Splice sites
3' ss Seq
TGTGTCTCCTCCCTCTCCAGAGA
3' ss Score
11.05
5' ss Seq
AAGGTATTT
5' ss Score
7.64
Exon sequences
Seq C1 exon
GAGCCCCAGTGCAGGAGGCTGCGAAAGTTGGGGGAGTGTGCTAGAAGGACTGCGGAGCGGAGCGCACGCGGGACCAGGCTGCGACTGGGTCGCTGGTCCCGGCCACAGGGAGTGGGAGCCGGCTGG
Seq A exon
AGATGCCCTGTATTCAAGCTCAATATGGAACACCAGCAACGAGCCCAGGACCGCGTGACCACCTGACCGGTGATCCCCTGGCCCTTGAGTTCGGCAAGCCTACCATGGACCTGGCCAGCCCCGAGACAGCACCTGCCGCACCTGCTACACTGCCCAGCTTCAGCACCTTCATGGACGGGTACACCGGAGAGTTTGACACCTTCCTCTACCAGCTGCCGGGGACGACCCAGCCGTGCTCCTCAGCTTGTTCCTCTGCCTCCTCCACGTCTTCTTCCTCATCCTCGGCCACCTCCCCCGCTTCGGCGTCCTTCAAGTTTGAGGACTTCCAGGTGTACGGCTGCTACCCGGGCACCCTGAGCGGCCCATTAGATGAGACCCTATCCTCCAGCGGCTCTGAGTACTATGGCAGTCCCTGCTCAGCCCCCTCGCCATCTACACCCAACTTCCAGCCGTCCCAGCTTTCTCCCTGGGACGGCTCATTTGGCCACTTCTCCCCGAGCCAGACTTATGAAGGCCTCTGGGCATGGACAGAGCAGTTGCCTAAGGCTTCTTCAGGGCCTCCGCCACCTCCAACCTTCTTCTCCTTCAGTCCTCCCACTGGCCCCAGCCCCAGCCTGGCCCAGAGTTCTCTGAAATTGTTCCCACCACCAGCCACCCACCAGCTTGGGGAGGGGGAGAGCTATTCCATGCCAGCAGCTTTCCCCGGCTTGGCACCCACCTCTCCGAACCGTGACACTTCCGGCATTCTGGACGCACCCGTGACCTCCACCAAGTCCCGGAGCGGGGCTTCAGGTGGCAGCGAGGGCCGCTGTGCAGTCTGTGGTGACAATGCTTCGTGTCAGCACTATGGGGTCCGCACCTGTGAGGGCTGCAAGGGCTTCTTCAAG
Seq C2 exon
CGCACAGTACAGAAAAGCGCCAAGTACATCTGCCTGGCAAACAAGGATTGCCCTGTGGACAAGAGGCGGCGGAACCGCTGCCAGTTCTGCCGCTTCCAGAAGTGCCTGGCTGTGGGCATGGTGAAGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000023034-'4-9,'4-6,14-9
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion (Ref, Alt. ATG (<=10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.505 C2=0.000
Domain overlap (PFAM):
C1:
NA
A:
PF0010513=zf-C4=PU(38.6=9.2)
C2:
PF0010513=zf-C4=PD(58.6=93.2)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGCCCCAGTGCAGGAGG
R:
CTTCCTTCACCATGCCCACAG
Band lengths:
256-1143
Functional annotations
There are 3 annotated functions for this event
PMID: 22002310
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning. ELM ID: ELMI002018; ELM sequence: SATSPA; Overlap: FULL
PMID: 22002310
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning. ELM ID: ELMI002019; ELM sequence: SAPSPS; Overlap: FULL
PMID: 22002310
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning. ELM ID: ELMI002306; ELM sequence: SPSTPS; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types