MmuINT0023261 @ mm10
Intron Retention
Gene
ENSMUSG00000047228 | A2ml1
Description
alpha-2-macroglobulin like 1 [Source:MGI Symbol;Acc:MGI:3039594]
Coordinates
chr6:128543932-128545134:-
Coord C1 exon
chr6:128544925-128545134
Coord A exon
chr6:128544057-128544924
Coord C2 exon
chr6:128543932-128544056
Length
868 bp
Sequences
Splice sites
5' ss Seq
CAGGTACTG
5' ss Score
9.04
3' ss Seq
GATGTCTTCCTTCTTCCCAGGCC
3' ss Score
9.69
Exon sequences
Seq C1 exon
GACACCACAGTGTGCCTTCTCGCTCTAACCCAATACATGAAGTTAACCGGCTCTAACCCTCAAAACACCATCACGCTGAGCTCAGAGGAGTCTGAGGAGGTTTTCTATGTTAACAGAAATAAACGCCTTCTGGTCCAGCACTCAAAAGTATCCAAAGGCCACCAACAATACACAGTGGATGTAGAAGGAGATGGATGCTCATTTATCCAG
Seq A exon
GTACTGGAAGCCTTCCTCACAGGAGAACTGAGCCTGTCTGTAAGAATCCAGACTAGTGTTCAGCTATGTGTGATGTGTTTTGTCATTTTGACTCTTCCTGTTTCCTGCTTCTCTCATATTTTTCTAATCAACAGCAGAAAATGCAACATACATGATAGAGAAGTTACTCACATTTTTATTATTTTTCAAAGTTAACATTTAGGGACTGGAGAGATGATTCTGTAGTTAAGAACATTGGCTGTTCTTTTAGAGGATCAGGGTTCAATTCTAAGCAGCCACATGGGGGCCACAACTCCAATTCCAGGAGCTCTGATGCCTTCCTCTGGCCTCTGTCAGCACTGAACATCACTATGTGGCGCATAGCTGCAGGCAAAACACCCACACACATAAAATTAAATTAAAAAATCTTTAAAAAAAATAGTAAAGTTGGCATACGGAGTAATAAGTTTCCTGATAGCATGTTCATGCCTGCTTTGTTATTTGTCTTCCTTCCCTACTCCCATCACCCCCCTTACCCCCTTTTGTTGAAGGACCACCCCAGCAATATCCCCCTTCTGCTTTCATGTCATATGCACCCCACTATCTCCCCAAATAAGAGCTCTTCTTTCCATTTCATAATGTTCTTTCTAGTCCCCCCAACACACACACATATATAAATTAAACATTTTTAGTAATTAAATTGGTTCTTCTGATAGAAAGCATTCTGCCCTCAGCCAGTCACATCATCACGCTGTCCCCATAAACATTTCGTTGATCCTGGTTCCCTGATGATAACACTATAAAGCACATTAATAATGGAGTTATACAGATAACAGGTTCTTCAGTGTTTACTGCAGGATGATTTTCAAGATGTCTTCCTTCTTCCCAG
Seq C2 exon
GCCACCCTCAGGTACAACGTGCCACTTCCTAAGGAGGCCTCAGGATTTTCCCTTTCCGTGAAAACTGGAAAAAGCAACTCTTCAGATGAATTCCAGACCAAGTTTGAACTCACGGTGACCCTCAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000047228:ENSMUST00000060574:30
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.071 A=NA C2=0.024
Domain overlap (PFAM):
C1:
PF076789=A2M_comp=PD(5.2=18.6)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACAGTGTGCCTTCTCGCTCTA
R:
TGAGGGTCACCGTGAGTTCAA
Band lengths:
328-1196
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types