Special

MmuINT0077973 @ mm9

Intron Retention

Gene
ENSMUSG00000037012 | Hk1
Description
hexokinase 1 [Source:MGI Symbol;Acc:MGI:96103]
Coordinates
chr10:61734337-61737350:-
Coord C1 exon
chr10:61737195-61737350
Coord A exon
chr10:61734571-61737194
Coord C2 exon
chr10:61734337-61734570
Length
2624 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGC
5' ss Score
8.7
3' ss Seq
TGGGCTTTTGTGCTCCACAGTGA
3' ss Score
8.02
Exon sequences
Seq C1 exon
GTTTGAGAAGATGATCAGTGGAATGTACCTGGGTGAGATCGTCCGTAACATCCTGATTGACTTCACCAAGAAAGGCTTCCTCTTCCGGGGACAGATCTCTGAGCCACTCAAGACCCGAGGCATCTTCGAGACCAAGTTTCTCTCTCAGATCGAGAG
Seq A exon
GTGAGCAGGGAGGGGAGGAGTTTCTGAGCACCATTTTGCTTTCGGCGAACTCCAAACTCGTGTCGAGAGTACTTCACTTCGCAGAGTATTTTTGAGGCTCATCCACTTTGGGTCCTCCCTTTTTAGGGCTGAGTAATATTCCATTGGATGGACCTATCACGTTTTGTTTTCCCGCATCTGCTACTGTCTGGCAGCTTGGGTGGTTCCCTTAAATGACTCTCTGAACATGGGGGGGGGGGTTGGGGAGTAAACATCTGTTTGGTCCCTGCTGTCGTGTCTCTTATGTATATACTCACAAGTGGACTGGCTGGGACCTGTGGTAATTCCCTTTTCAGTTTCCTGAGGAACCACCATATTGTTTTCCCAAACGGCCACTCCCATTTGCCATCCCCAGCATCCTCACGTAAGCTGCCAGTTTCTAACAGCTTAATGGCAAAGACAGAACAAACCAGAGCTCCATAGGTTCTGTAAGGCCTTTTAAAGATTGGTATTGGGGGGGGGGCGACAAATAGTACACTGAGAAAAACATTTGCTTTGCGTGTGACAAGAGGCAGAAGCATGGTGGGGGCTGGGGACGCAGATCCCAACAGTTCCGACCCCGTGAGCCTCCCTACCCTCGACTGTGCTTCCAAGAATGCCTAAGTTTTCCATTTCCTCCTCTTGGGCATGATGAAAGCTTGACGTAAGGGTTACAGGCCAGAGGATCTGGAGTTATAGGCCCAACTCATCTACGTGGTGAATTTGGGGCTAGCCTTGGCTATTTGAGATCTTGTAGTGACTTCGTACATGCAGTGTGTGTACAATTGCACACACACAAGTCTTTGAGAAAGGCTAGCCAGTCTTATCTCAGCTCTTTCAATTTACTAGGAGAAGGGAAAGTCCTGGGGTACACTAGGTCGCTCATATGACCCTTAAGGGAACAAACGTCATCTTGGCTGACGTAGAATAATGCAAATTAAGCCAAGGTGTGGTGACAAAGGGCATTAAAAAATTACTTCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGACATGTGTCAGTCAGAGGTTTCCTTTCTCCTGGCTAAGAGAGAAGGCCGATCCCTCGGCTAGCCTCTCCTCTTGCTGTAGGGGTGCTTCTGGCATCAGATTTAGTTCATTGGACTTTCATAACCAGTGCTGTCCCCACTGAGCCACCTCCCAGCCCTGCTGTTGTCCTTAGGAAATTATAGTTTCAAAGTGATCTCTTCTAGCTGGGCGGCGAGGTGAGGCGGGAAGCCGGTGAGCCTCTAGGTCACCTTGGACAGCCCTCTCTCTCCAACAGAAGAGGAAGAAGAGGGGGAGAAAAGAATGTAATGGCATTCCCTGGGGTCACTGGGATTAGGAAAAGTTTTAAAATTTTTCAGCTTTAATTTCTGTAGTCTAGCATGTGGTACACGCCTCTAATCCCAGCACTCTGGAGGCAGAAGCAGGCAGATCAATGAGATCCAGGCCAGCCTGGACTACAGAGTAAGTTCCAGGACAGCCAGGGCTACACAGAGGAACCCTGTCATAAAAAACACCACCACCACCACCAAAAACCAAAACAGTCTTCAGTCTTCCTAATGCTGCAACCCTTTAATACAGTCCCTCATGTTGTGGTGACCCCCCCAACCATAAAATTATTTTCATTGCTCCCTCAAAACTGTAATTTTGCTACTGTTATGAATCATAGGGTAAATACCTGTGTTTACTGATGGTTTTAAGTGACACCCATGGAAGGGTCATTAGACTTCCAAGGAGTCACAATCCACGGGGTTAAGAATCACTGGTTTAGACACACACATACACACACACACACACACACACACACAAAAAAAAAAAAAAAAAACAAAACAAAACAAAAAAAAAAAAGAATCACTGGTTTAGGGCTGGCGAGATGGCTCAGCGGGTAAGAGCACTGACTGCTCTTCCAAAGGTCCTGAGTTCAATTCCCAGCAACCACATGGTGGCTCACAACCATCTGTAGTGAGATCTGACGCCCTCTTCTGGGGTGTCTGAAGACAGCTGCAGTGTACTTATGTATAATAATAAATAAATCTTAAAAAAAGAAAAAGAAAAAGAGCCACTGGTTTGAATCGGTGAGCCAGAGAGATTATTGCTCATTGGTTAAGAGCACTCACAGCTCTTGCGGAGAGCCTGAGTTTGGTTCCTAGCACTTCATTCAGGCTGCTCACAGCCACCTGTACCTCGAGCTCCAGGGGATCTGACACCTCTGGCTGCCGCAGGAACCTGTAACTCATGCACACAGACATACACAATTAGAAGCCGAAGACAGGAGAGATGGCTCTCACCCCTTCTGAAGTTCACAGTGTGATTGTCAGCTCGCACAATCAGGCAAGTCACAGCTTCATATAGCTCCAGATCCAGGGGATCTGACACCCTCCTCTGGCCTCTATGGGTACCTGTGGCGTATACATAGACACACCTACCTACAAATGTGTGTGTGTGTGTGTATTCTTTTAATTTAATCTATTTAGAAGGGGAATAAACCCCTGGGATGCCATTCATAGACAAGCAGAATGCTTTGGACCGGTCCTTGTTCCAAGGGTTCCATGGGCCTGCTCCATCCAGCTCACTGGGCTTTTGTGCTCCACAG
Seq C2 exon
TGACCGATTAGCGCTGCTCCAGGTGCGGGCCATCCTTCAGCAGCTGGGTCTAAACAGCACGTGCGACGACAGTATCCTGGTCAAGACCGTGTGTGGGGTGGTGTCCAAGCGGGCGGCCCAGCTGTGTGGTGCCGGCATGGCCGCCGTGGTGGAAAAGATCCGAGAGAACAGAGGCCTAGACCACCTGAATGTAACCGTGGGCGTGGACGGGACGCTCTACAAACTCCATCCACA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000037012-Hk1:NM_010438:20
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0372711=Hexokinase_2=FE(21.7=100)

							
A:
NA

							
C2:
PF0372711=Hexokinase_2=FE(32.5=100)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000131080





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000072195, ENSMUSP00000097282, ENSMUSP00000111946, ENSMUSP00000118601
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr10:69395106-69398594 
LOW PSI
HsaINT0076355
(HK1)
Human
(hg19)
chr10:71154862-71158350 
LOW PSI
HsaINT0076355
(HK1)
Rat
(rn6)
chr20:31914304-31916641 
LOW PSI
RnoINT0070951
(Hk1)
Cow
(bosTau6)
chr28:25919174-25922342 
LOW PSI
BtaINT0072296
(HK1)
Chicken
(galGal4)
chr6:10492895-10493554 
LOW PSI
GgaINT1014840
(HK1)
Chicken
(galGal3)
chr6:12002944-12003603 
GgaINT0040808
(F1NEI1_CHICK)
Zebrafish
(danRer10)
chr13:22845780-22845882 
LOW PSI
DreINT0078059
(hk1)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"