MmuINT0092592 @ mm9
Intron Retention
Gene
ENSMUSG00000027070 | Lrp2
Description
low density lipoprotein receptor-related protein 2 [Source:MGI Symbol;Acc:MGI:95794]
Coordinates
chr2:69341444-69343386:-
Coord C1 exon
chr2:69343138-69343386
Coord A exon
chr2:69341656-69343137
Coord C2 exon
chr2:69341444-69341655
Length
1482 bp
Sequences
Splice sites
5' ss Seq
CAGGTAATT
5' ss Score
8.55
3' ss Seq
TTTTTCCTTTCCCTACACAGCAT
3' ss Score
10.18
Exon sequences
Seq C1 exon
ATCAAGACAGCTGCTTACATTTTAATGGTGGCTGTACTCACCGGTGCATACAAGGGCCCTTTGGAGCCACCTGCGTGTGTCCAATAGGATACCAACTTGCCAATGATACCAAGACCTGTGAAGATGTAAATGAGTGTGATATTCCAGGCTTTTGCAGCCAGCACTGTGTCAACATGAGAGGGTCCTTCCGGTGCGCTTGTGACCCAGAATATACATTGGAAAGTGATGGGCGGACTTGCAAAGTCACAG
Seq A exon
GTAATTATTAAGCTTGAAAGGGAACTAACTCCAGGAAATTTAATAGCCTCTCTCAGTGTAAGACTGATTGTCTAGTCAGTCTGACTAGACAACTTATTCAATGCCTTTTGACCCATATGAAAGTGAATACGCTAGATATCAGAATGTTGATTCAGCCGCTCTCAAAATGATTCAACAGAGGAGGGTTTGAAAGTTTCCTGATTGCAGGACACCATGGTTTATGCCTTTTATCCCAGCACTTGGGAGGTAGCACCAGATTAATTAGCCTGGGCTTTATAGTGAGTTCAAGGCCAGCCTAGGCTACAAAAATACCAAAGCTTTGCTTCAAGAATACCAATGTCAAACAAGGAGCCTTTCTTTTCAAGGAGGCTGGATGAAACAGTCTAAGGGACAGACTGTTTTTTAAAAAAAATATTTAATTATTTATTTTACATACATGAGTACACTGTACACTGTACACTGTACAGATGGTTGTGAGCCTTCATGTGGTGTTGTTGCGAATTGAATTTTAGGACCTCTGCTTGCTCTGGTCAACCCACTCACTCTAGTCGACTTTGCTCTCTCAGTCCCTGCTCGCTTAGTCCCAAAGATTTATTTATTATTATACATAAGTACACTGTAGCTATCTTCAGATGTCCCAGAAGAGGGCATCACATCTCATTATGGATGGTTGTAAGCCACCATGTTGCTGCTTGGATTTGAACTCAGGGCCTTCCTAAGAGCAGTCAGTATTCTTACCCGATGAGCCATCTCCCCAGCCCAACAGACTGATTCTTATTATCTGAAGTTCCACCCAAGATCCAAGAAGTTTGCTCTAGTCTGTTCTTTCCCTTAGAAAATAGGCTAGGCAAAGAAAGGTCCTTTTCAGGAAGTAGATCCATCATTGTTATTGATGCATTATTGGTCAGAACTCAGTCATTTGGTTCTAGCAGCTGCAGGGAAGGCAGAGACCAGTCTCTATTTGAGTAGCCTTAGGCCAACCTAAATGTAGTGTGACTTAACACTAAAAAGACCAGGGGGAAAGGAATATTCATTGATGGAACTCTCTGCTACACCTAAAGGTTTGGGAGAAAACAAAAATACTCAAAACTTGGTTCCTGCCAAGAATCAAGCCTACAGTCTGCTAAGATAGAAAGCAAATTGCAACAAGCAAGTCAAGGATCAATGTATGAACAGCTCACTCCATACTGGTACTTAGATGCCCACTGCAATAATCCAAGAGAGAAAGCTTTTTCAGAACATAACTATTTTACGTGCCAATGAGTATCCATGAGCAAACAAGGTTCCCCTGATCCCGCTTAGCTCTGATGAGGTCAGGGATGTTCAGGGTGATATGTCTGTAGACAACGTGATTATTTCTCCCATTTCTCTAGTTTGGTACCACGCACTTGATGTTGGGGAGACTTTAAAACTGTATTTAATTGTATTTTTCTTTCAGATTCATTGACGGTTTCTTTTTCTTTTTTTCCTTTCCCTACACAG
Seq C2 exon
CATCTGAAAATCTGCTGTTAGTTGTAGCCAGTCGTGACAAAATCATTATGGACAATATCACTGCCCACACGCACAACATCTATTCTTTGGTCCAGGATGTTTCTTTTGTGGTTGCTCTGGATTTTGATTCAGTCACTGGTCGTGTCTTTTGGAGTGACTTATTGGAGGGTAAAACCTGGAGTGCCTTTCAAAACGGAACCGACAAGAGAGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027070-Lrp2:NM_001081088:26
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0005713=Ldl_recept_a=PD(9.3=4.8),PF146701=FXa_inhibition=WD(100=42.9),PF146701=FXa_inhibition=WD(100=41.7)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CATACAAGGGCCCTTTGGAGC
R:
ACTCCAAAAGACACGACCAGT
Band lengths:
358-1840
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: