MmuINT0092650 @ mm10
Intron Retention
Gene
ENSMUSG00000027070 | Lrp2
Description
low density lipoprotein receptor-related protein 2 [Source:MGI Symbol;Acc:MGI:95794]
Coordinates
chr2:69533453-69535058:-
Coord C1 exon
chr2:69534909-69535058
Coord A exon
chr2:69533573-69534908
Coord C2 exon
chr2:69533453-69533572
Length
1336 bp
Sequences
Splice sites
5' ss Seq
GTGGTGAGT
5' ss Score
8.95
3' ss Seq
GTTTCTTTCCTTCTGTTTAGGTA
3' ss Score
11.43
Exon sequences
Seq C1 exon
AAAGTAACCAACGTCATCATACATGTTACCCAAGAGAATGGGCGTGTCCTGGGTCTGGACGATGCATCTCAATGGATAAAGTTTGTGATGGAGTTCCCGACTGTCCAGAAGGAGAGGATGAGAACAATGCCACAAGTGGACGATACTGTG
Seq A exon
GTGAGTGTGGGAGCTGTATATGGCTCACTTCCTGATAAGAAGGTTTCTAGACCAGACTCTCAAATGCAGAGAATATCAGCTGACATTTCCACAACAAAATAGCTCGGTTCAGTCACTTCATTGACATTTATTATGTCTCATGGCAGTTCTTGCCTATACCAGCCCACTGTCTAACCCACACTTGGTTTCACAATGGTGGAGAGTAGACCCTATCATTTGAACAATTTTAAGTCTCTGCAAGCCATGTTTGCTAAGGTATTGACCACATTCAGGTGAGGCCAGAGTGGAACAAAAGTATATGCCAACAAGGAAAGTTTTTTTTTTTTTTGAGACAGGGATTCTCTGTGTAGCTTTGGTTGTCCTGGAACTCACTTTGTAGACCAGGCTGGCCTCGAACTCAGAGATCCGCCTGCCTCTGCTTCTGCCTCTGCCTCCCAAGTGCTGGGATTAAAGGTGTATGCCACCACGCCTGGCTGGAAGTTGTTTTAATAACAAGTATGATGACTTTAACATGGGAGCATCTCATCTTGTGATACTAGGGCTCAGACATAAAGAATTATGGGAATTATGCCCTACCCATTGAACTTGTTACATACGTTTGATATCTTATCTTATCCTGGTCTTATTTAGATATTCTAAGACAAGCTTCTGATTCCTAGGGTGTGTAAGTTGTCTTCTAGCGGTTCTTAGGATAGGTAATGAACTGAATTGGCCATTTGGTATCTAAGCACCATTTTTGTCTCTCTCCCCCTAAGTCAATCCAGTTCTGAGAACATCTCACATCTCAAAGGGGACAATTTTGAACTTGATCTCATCATTTCGACACTAACTCAGTTGGTGATTGCACAGATGAGCACATGTCCTTCTAACTCCAAGGATCCCCTGACCCCAATACTTGTCATATCTAAAAGTCTTTCCATTCAGCTTAGAAGATTTAGTATAAAAGCTTCAGAATAAACAAATGATATGTAATCAGTGGCCAAAGTTTTGAGAAGAGATATTAACAGGAAAAACAAACAAAACTAATCTCCTGAAAGCCTACTATTGCAAGCCAGCCACAGTCAGAGCTACCAAAGCTTATGACCTGATTTTTCATGAATGGAGTTAACAGCCTTTTATGTCTACAGGTAACAGTAGCTGTAATATGAAAAGAAAAAGAGGTTTAAGAAACACAAAGCATTTGCTACGTGGTATTGCAGGAGGTGGCAGGCTCTCCTGCTGTATTGCATGCTCATTGTTTTTTTTTTTTTTTTTTTTTTTTTTCTGTTTGGAAGTTACTAGGTAAACTAGTCTTGTCCAGAGCCATCCAGTTAGCAGTTTCTTTCCTTCTGTTTAG
Seq C2 exon
GTACGGGTCTCTGCTCTATCTTAAACTGTGAGTACCAATGCCATCAGACGCCATATGGAGGAGAATGCTTCTGCCCGCCAGGTCATATTATCAACAGCAATGACAGCCGTACTTGCATTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027070:ENSMUST00000080953:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0005713=Ldl_recept_a=WD(100=76.5)
A:
NA
C2:
PF146701=FXa_inhibition=WD(100=90.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAAGTAACCAACGTCATCATACATGT
R:
CAATGCAAGTACGGCTGTCAT
Band lengths:
270-1606
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types