Special

MmuINT0162771 @ mm9

Intron Retention

Gene
ENSMUSG00000033177 | Tmprss7
Description
transmembrane serine protease 7 [Source:MGI Symbol;Acc:MGI:2686594]
Coordinates
chr16:45664285-45667772:-
Coord C1 exon
chr16:45667665-45667772
Coord A exon
chr16:45664396-45667664
Coord C2 exon
chr16:45664285-45664395
Length
3269 bp
Sequences
Splice sites
5' ss Seq
GTGGTAGGT
5' ss Score
7.23
3' ss Seq
CTTTCTGCCTTTCACCACAGTGA
3' ss Score
9.37
Exon sequences
Seq C1 exon
CGTGTCCTGCAGGATCTTTTAGGTGCTCCTCCGGTTTGTGTGTCCCTCAGGCCCAGCGTTGTGACGGAGTGAATGACTGTTTCGACGAAAGTGATGAACTTTTCTGTG
Seq A exon
GTAGGTGTAATACAATTTCATTATGAATATATAACTTCTTGGAATCATTGCTGCTGCTGGTTGACCCCAGTCTTTGTAGATGCTGCATGTCTGTCCCTAGCTATCCTGAAACTCAATGGCTTAATTAACCCCATCATTTATTCTTGACCATGTATTCATGGTTGCATAGGCTCTCCTTAGCTGAGTGGCTCAGGCTCAAGCAATGGGTTGTTCTGTGCTAAGCTCCTTCCAGGTTGGCGTCATGGCTATTCTTTATGGCCCGGTCTTTCATGGAGTCAAGGAGCTAATAGAAACAAAAGCAAGGAAAAGTAAACATCAACACCTGGCTTCCAATAAGGGCTGGCCTTGCAAAACTTATATCATATTCTGTTGCTCCAAAGAAGTCGAATGGCTAAGCCCATGTTCAAGAGAGAGGTAAAATTATTTTGTATACCTTGAGGTCATGTCGTGGCATATTCTCACTATAGGGAGTAATGTCTTGTGGCTAATGACCTAACCTACCACAACTGGGTGTAAACACAAAGATCCTATACCTTAAGGAGCTCAGAATCTGAAGGAAGTTCAGTTCAGTGTGGTTGCTGATACAACACAGGTGTCGTGAACAAACTAGACAACTGTTTAGTTGATTTATTTTTTCTGTTACAGTTACTTCCTTTTTATTGAAAAAGCTTTCTTTTTCATGCAATATATTCTGGTTCAGGTTTCTCCTTCCCATGCTCCTCTGAGAGCGTCATCATCTTTCTCTACCCATCCAACTCCACCATTTTTCTTTTTCTCTCTTGAGAAAATAAGTAACCAATCAAGCAAAACTTAATAAACAAATGAAAAGAAAAACACACACACACACACACACACACACACACACACACACACACACAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAAAGCCCCAAATCTATAAAAACACAAAACTGGAAACCTTAATATACAATCAAAAGACAAGTAAGATTACAAAGAGAGAGAGAGAGAGAGAGAGAGAGAGTAAAAAAGGAAAGAAAAATGCCAATCAAAGCAATATGGGACTAACATTTATAAAAATACTATTGAGCTGGTTCTGTGTTGTCTATCTACTACTGCTTGGCACGGGGCCTGCCCTTAAGTGTGGTCTAATGTTTCCTTTGCAAGCAGATGTCAGTTGGAGATAGCTTCCTGTTTAGTTCATGTCCACTTCCCTTTCTGAGTGCTGGGTTCTGGTCTGCTTTGACCCTATGGAGAGCCTGTACGTGCTGCCACAGTCTCTGTGGGTTCATATGTGCATCAGTCCTGTCCTTTCTGGAAGACACCATTTCCTTAGAGTCCTCTGGATCTTAGAGGCTTTCTGACTCATCTTCTTCATACACATTGACTGCTGGTAACAACTAAGGGATGGAAACAGGATACTCCTAATCTAGACAGATAATATAGATCATAATTTTCATTGTTATTTGCAACCTACTCCTGTATCGATTTCTAGTTTATAGGACAACAGGAAGATAGTTTAAGGGCAATATAAAGTTATTGGCAATAGTTTTTTAAATACTCTTGTAACAAAAATGGTATGTAATCTTTCCATATCTTTGGGGAAACATTTCATTTAATATAATACAGCTATGTAAAATTATATTCATAAAATGACCTCTGCATCTACAACTGTGTATGTGTGGGTGTGATACTGGGATCAAGCCTAGTGTCTTGCATGTGCTAGGCAAATACCCTAGCCCTGAACTACATCCCTAATCCCTTTGTACATTTTCAAATTTACAAAACAAAATAAAATCATCTTAATTTATGGCTCATTAGCAATCTAAATCTATAAAATCTTTGATTTCTTAAGAAAATAGATGCTGACAATTTTAGTGATTGAAGGTTTTTTTTTTCCATTACTGTTCTTTGCTCTGATGCCCCAGATGAAAGCTATTGGCATTCTTTTATAATAAGGACTAGTGATTGGTATCATTGTATTCCATTGCATCTTTTCCGGAGCCATTCTGTGGATGTTAACTAGGTACCTTTTGGCAACAACCAAGTGCTTTAAGGCAGTAGTGTACTCCACTCACCCTTTGAGGGGTGGGGACAGGGACTGAGTAACACAAGAAATACACTGGTAAACAAAAAAAAAAAAAGACAGTAAAACTGAAAAATTTCACAATCTAGAGATCACAGAGAAACCTTCCTTTCAGACGATGCTTTGCTGGTATACTATGTATGCCATAGATGTAAAGGTGATTCAAGAAGTCTGTCAAAGAAACAGTCGTTTTTAGGGTATATATCCATCAGAGTAAAACAAGTTTAAAGTGGTTTCACATGTGGGCTACGAGTCTGATATCCTTTAAGGTCTCACCTTCATTAATTAATCCACCAAGGTTTTTGTGAGCATCTAATATTTTTTGGTCAGGGACCTGAGGTAGAGAGATGAGTGAGACAAAATCCCCCATTTCAGCCCACTACACCTTTCTCAGGAGGGTAGGCAAGTTCAACTCAGATAACAGGTGATGCGAATTATTTTTCTTTAAAAAAAAAAATTAGTGATGCCAGGTGTCTTAGTTAGAGTTTTACTGCTGTGAACAGACACCGTGACCAAGGCAACTCTTATAAGGACAACATTTAAGTAGGGCTGGCTTACAGGCACAGAGGTTTAGTTCATTAACACCAAGGTGGGAACACATGGCAGTACCAGGGAGGCATGGTGCAGGCAGAGCTGAGAGTTCTACATCTTCATCTCAAGACTTCTAGGAAGACTGGCTTCAAGGCCACTAGAGTGAGGGTCTTAAGCCCATGACCACAGTGATACACCTACTCTAACAAGGCCCAACCTCCTAATAGTGCCACTCCCTGGGCCAAGCATATACAAACCATCATACCAGGCATGGTGGAGCAGATCTTTAACCCAAGCACACAGAAGGCAGAAGCAGGTGGATCTCTTTGAGGTCAGCTAGGATTACACAGTGAGAGCTTGTCTCAAAAAATAAGAGAAAACATGATTATTTATGATGCAATGAGTTGAAGTTACATAAACCACCAGATTTAAACACATTGACACCATAGCAAAACCAAGATCCGATAGGAATTTCATCAGAGTAAGGAATTATACTAGCCATCCCCTTTCTTCCTGGGATTTATTACTTGAAGGTAGACACATTCTATCACGCTTTTGTATTTTCCGTGATAATGTTCATACCTTTAGAGGGGTACTGTTGGCCATCAGAGAACCCAGCTGATGCCCTGTTGTTCATGACCTTTCTGCCTTTCACCACAG
Seq C2 exon
TGACTGTAAAACCTGCCTGCAACAGCAGCAGCTTCCGGCAGCATGGCCCTCTGGTCTGTGATGGCTTCCGGGACTGCGAGGATGGTCAGGACGAGCAAAACTGCACTAGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000033177-Tmprss7:NM_172455:12
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0005713=Ldl_recept_a=PD(94.6=94.6)

							
A:
NA

							
C2:
PF0005713=Ldl_recept_a=WD(100=55.3)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000044975





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000110209, ENSMUSP00000127789
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr3:112063633-112066391 
HsaINT1044712
(TMPRSS7)
Human
(hg19)
chr3:111782480-111785238 
HsaINT0169764
(TMPRSS7)
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr1:57255101-57257602 
BtaINT0150480
(TMPRSS7)
Chicken
(galGal4)
chr1:88004030-88004658 
ALTERNATIVE
GgaINT0119257
(TMPRSS7)
Chicken
(galGal3)
chr1:91909343-91909971 
GgaINT0119257
(E1C7W0_CHICK)
Zebrafish
(danRer10)
chr24:21702711-21703411 
DreINT0021351
(TMPRSS7)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"