FBgn0001180 @ dm6
Biotype
protein_coding
Gene Symbol
hb
Description
The gene hunchback is referred to in FlyBase by the symbol Dmelhb (CG9786, FBgn0001180). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:8690980..8697822. Its molecular function is described by: DNA-binding transcription factor activity, RNA polymerase II-specific; sequence-specific DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity. It is involved in the biological process described with 15 unique terms, many of which group under: stem cell fate determination; animal organ development; positive regulation of biological process; central nervous system development; regulation of cell population proliferation. 140 alleles are reported. The phenotypes of these alleles manifest in: tracheal system; embryonic ganglion mother cell; larval metathoracic segment; embryonic/larval proventriculus; neuron projection bundle of ventral nerve cord. The phenotypic classes of alleles include: embryonic/larval segmentation phenotype; lethal - all die before end of larval stage; increased mortality; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed within 00-06 hour embryonic stages.
Coordinates
chr3R:8690980-8697822:-
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
EVENTS AND AS PROFILES[edit]
Associated events[edit]
Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Orthologous genes[edit]
| Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
|---|---|---|---|---|
| Human | hg38 | ENSG00000084093 | REST | 1-to-3 |
| Human | hg38 | ENSG00000151612 | ZNF827 | 1-to-3 |
| Human | hg38 | ENSG00000163795 | ZNF513 | 1-to-3 |
| Human | hg19 | ENSG00000084093 | REST | 1-to-3 |
| Human | hg19 | ENSG00000151612 | ZNF827 | 1-to-3 |
| Human | hg19 | ENSG00000163795 | ZNF513 | 1-to-3 |
| Mouse | mm10 | ENSMUSG00000029249 | Rest | 1-to-3 |
| Mouse | mm10 | ENSMUSG00000043059 | Zfp513 | 1-to-3 |
| Mouse | mm10 | ENSMUSG00000071064 | Zfp827 | 1-to-3 |
| Mouse | mm9 | ENSMUSG00000029249 | Rest | 1-to-3 |
| Mouse | mm9 | ENSMUSG00000043059 | Zfp513 | 1-to-3 |
| Mouse | mm9 | ENSMUSG00000071064 | Zfp827 | 1-to-3 |
| Rat | rn6 | ENSRNOG00000005298 | Zfp513 | 1-to-1 |
| Cow | bosTau6 | ENSBTAG00000011789 | MGC157163 | 1-to-4 |
| Cow | bosTau6 | ENSBTAG00000012738 | ZNF827 | 1-to-4 |
| Cow | bosTau6 | ENSBTAG00000019359 | 1-to-4 | |
| Cow | bosTau6 | ENSBTAG00000019518 | ZNF513 | 1-to-4 |
| Chicken | galGal4 | ENSGALG00000009982 | ZNF827 | 1-to-4 |
| Chicken | galGal4 | ENSGALG00000016516 | ZNF513 | 1-to-4 |
| Chicken | galGal4 | ENSGALG00000028322 | 1-to-4 | |
| Chicken | galGal3 | ENSGALG00000009982 | ZNF827 | 1-to-4 |
| Chicken | galGal3 | ENSGALG00000016516 | 1-to-4 | |
| Zebrafish | danRer10 | ENSDARG00000019961 | znf513 | 1-to-4 |
| Zebrafish | danRer10 | ENSDARG00000076171 | znf827 | 1-to-4 |
| Zebrafish | danRer10 | ENSDARG00000101203 | ZNF513 (2 of 2) | 1-to-4 |
| Zebrafish | danRer10 | ENSDARG00000103046 | rest | 1-to-4 |