FBgn0001218 @ dm6
Biotype
protein_coding
Gene Symbol
Hsc70-3
Description
The gene Heat shock 70-kDa protein cognate 3 is referred to in FlyBase by the symbol DmelHsc70-3 (CG4147, FBgn0001218). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (1 unique). Gene sequence location is X:11801696..11807117. Its molecular function is described by 7 unique terms, many of which group under: protein binding; binding; nucleoside-triphosphatase activity; drug binding; protein folding chaperone. It is involved in the biological process described with 10 unique terms, many of which group under: protein folding; multicellular organismal process; 'de novo' posttranslational protein folding; organic substance catabolic process; intestinal stem cell homeostasis. 50 alleles are reported. The phenotypes of these alleles manifest in: larva; central nervous system; pupa; interneuron; sensory organ cell. The phenotypic classes of alleles include: lethal - all die before end of larval stage; increased mortality during development; increased mortality; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
Coordinates
chrX:11801696-11807117:-
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
EVENTS AND AS PROFILES[edit]
Associated events[edit]
Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Orthologous genes[edit]
Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
---|---|---|---|---|
Human | hg38 | ENSG00000044574 | HSPA5 | 1-to-1 |
Human | hg19 | ENSG00000044574 | HSPA5 | 1-to-1 |
Mouse | mm10 | ENSMUSG00000026864 | Hspa5 | 1-to-1 |
Mouse | mm9 | ENSMUSG00000026864 | Hspa5 | 1-to-1 |
Chicken | galGal4 | ENSGALG00000001000 | HSPA5 | 1-to-2 |
Chicken | galGal3 | ENSGALG00000001000 | GRP78_CHICK | 1-to-2 |
Zebrafish | danRer10 | ENSDARG00000103846 | hspa5 | 1-to-1 |