FBgn0002023 @ dm6
Biotype
protein_coding
Gene Symbol
Lim3
Description
The gene Lim3 is referred to in FlyBase by the symbol DmelLim3 (CG10699, FBgn0002023). It is a protein_coding_gene from Dmel. It has 8 annotated transcripts and 8 polypeptides (4 unique). Gene sequence location is 2L:19079256..19108427. Its molecular function is described by: sequence-specific DNA binding. It is involved in the biological process described with: motor neuron axon guidance; regulation of transcription, DNA-templated; positive regulation of gene expression; nervous system development. 37 alleles are reported. The phenotypes of these alleles manifest in: circulatory system; tagmatic subdivision of integument; segmental nerve; melanotic mass; adult. The phenotypic classes of alleles include: lethal; phenotype; increased mortality; increased mortality during development. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 06-24 hour embryonic stages, during early larval stages.
Coordinates
chr2L:19079256-19108427:-
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
EVENTS AND AS PROFILES[edit]
Associated events[edit]
Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Orthologous genes[edit]
| Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
|---|---|---|---|---|
| Human | hg38 | ENSG00000107187 | LHX3 | 1-to-2 |
| Human | hg38 | ENSG00000121454 | LHX4 | 1-to-2 |
| Human | hg19 | ENSG00000107187 | LHX3 | 1-to-2 |
| Human | hg19 | ENSG00000121454 | LHX4 | 1-to-2 |
| Mouse | mm10 | ENSMUSG00000026468 | Lhx4 | 1-to-2 |
| Mouse | mm10 | ENSMUSG00000026934 | Lhx3 | 1-to-2 |
| Mouse | mm9 | ENSMUSG00000026468 | Lhx4 | 1-to-2 |
| Mouse | mm9 | ENSMUSG00000026934 | Lhx3 | 1-to-2 |
| Rat | rn6 | ENSRNOG00000003595 | Lhx4 | 1-to-2 |
| Rat | rn6 | ENSRNOG00000018427 | Lhx3 | 1-to-2 |
| Cow | bosTau6 | ENSBTAG00000003992 | LHX4 | 1-to-2 |
| Cow | bosTau6 | ENSBTAG00000011124 | LHX3 | 1-to-2 |
| Chicken | galGal4 | ENSGALG00000003928 | LIM3 | 1-to-2 |
| Chicken | galGal3 | ENSGALG00000003928 | LHX3_CHICK | 1-to-2 |
| Zebrafish | danRer10 | ENSDARG00000003803 | LHX3 | 1-to-2 |
| Zebrafish | danRer10 | ENSDARG00000039458 | lhx4 | 1-to-2 |