Special

FBgn0002522 @ dm6

Biotype
protein_coding
Gene Symbol
lab
Description
The gene labial is referred to in FlyBase by the symbol Dmellab (CG1264, FBgn0002522). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:6661427..6678590. Its molecular function is described by: DNA-binding transcription factor activity, RNA polymerase II-specific; cis-regulatory region sequence-specific DNA binding; protein heterodimerization activity. It is involved in the biological process described with 7 unique terms, many of which group under: anatomical structure development; developmental process; system development; cell differentiation; cellular developmental process. 40 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval brain; visual system; brush border; postgena; wing blade. The phenotypic classes of alleles include: increased mortality; phenotype; some die during P-stage; partially lethal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages.
Coordinates
chr3R:6661427-6678590:-
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)


Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000120094 HOXB1 1-to-1
Human hg19 ENSG00000120094 HOXB1 1-to-1
Mouse mm10 ENSMUSG00000018973 Hoxb1 1-to-1
Mouse mm9 ENSMUSG00000018973 Hoxb1 1-to-1
Rat rn6 ENSRNOG00000001572 Hoxd1 1-to-3
Rat rn6 ENSRNOG00000005628 Hoxa1 1-to-3
Rat rn6 ENSRNOG00000058485 Hoxa1 1-to-3
Cow bosTau6 ENSBTAG00000007603 HOXB1 1-to-1
Zebrafish danRer10 ENSDARG00000025899 pnx 1-to-1