FBgn0002522 @ dm6
Biotype
protein_coding
Gene Symbol
lab
Description
The gene labial is referred to in FlyBase by the symbol Dmellab (CG1264, FBgn0002522). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:6661427..6678590. Its molecular function is described by: DNA-binding transcription factor activity, RNA polymerase II-specific; cis-regulatory region sequence-specific DNA binding; protein heterodimerization activity. It is involved in the biological process described with 7 unique terms, many of which group under: anatomical structure development; developmental process; system development; cell differentiation; cellular developmental process. 40 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval brain; visual system; brush border; postgena; wing blade. The phenotypic classes of alleles include: increased mortality; phenotype; some die during P-stage; partially lethal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages.
Coordinates
chr3R:6661427-6678590:-
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
Orthologous genes[edit]
Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
---|---|---|---|---|
Human | hg38 | ENSG00000120094 | HOXB1 | 1-to-1 |
Human | hg19 | ENSG00000120094 | HOXB1 | 1-to-1 |
Mouse | mm10 | ENSMUSG00000018973 | Hoxb1 | 1-to-1 |
Mouse | mm9 | ENSMUSG00000018973 | Hoxb1 | 1-to-1 |
Rat | rn6 | ENSRNOG00000001572 | Hoxd1 | 1-to-3 |
Rat | rn6 | ENSRNOG00000005628 | Hoxa1 | 1-to-3 |
Rat | rn6 | ENSRNOG00000058485 | Hoxa1 | 1-to-3 |
Cow | bosTau6 | ENSBTAG00000007603 | HOXB1 | 1-to-1 |
Zebrafish | danRer10 | ENSDARG00000025899 | pnx | 1-to-1 |