FBgn0002941 @ dm6
Biotype
protein_coding
Gene Symbol
slou
Description
The gene slouch is referred to in FlyBase by the symbol Dmelslou (CG6534, FBgn0002941). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:21548661..21557182. Its molecular function is described by: sequence-specific DNA binding; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: cell differentiation; muscle organ development; positive regulation of transcription by RNA polymerase II; muscle cell fate determination; negative regulation of transcription by RNA polymerase II. 14 alleles are reported. The phenotypes of these alleles manifest in: myoblast; embryonic/larval dorsal vessel; adult external thorax; ventral acute muscle 2; cardioblast. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; lethal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 06-24 hour embryonic stages.
Coordinates
chr3R:21548661-21557182:-
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
Orthologous genes[edit]
Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
---|---|---|---|---|
Human | hg38 | ENSG00000229544 | NKX1-2 | 1-to-2 |
Human | hg38 | ENSG00000235608 | NKX1-1 | 1-to-2 |
Human | hg19 | ENSG00000229544 | NKX1-2 | 1-to-2 |
Human | hg19 | ENSG00000235608 | NKX1-1 | 1-to-2 |
Mouse | mm10 | ENSMUSG00000029112 | Nkx1-1 | 1-to-2 |
Mouse | mm10 | ENSMUSG00000048528 | Nkx1-2 | 1-to-2 |
Mouse | mm9 | ENSMUSG00000029112 | Nkx1-1 | 1-to-2 |
Mouse | mm9 | ENSMUSG00000048528 | Nkx1-2 | 1-to-2 |
Rat | rn6 | ENSRNOG00000005113 | Nkx1-1 | 1-to-2 |
Rat | rn6 | ENSRNOG00000017006 | Nkx1-2 | 1-to-2 |
Cow | bosTau6 | ENSBTAG00000009166 | GSX1 | 1-to-2 |
Cow | bosTau6 | ENSBTAG00000020918 | NKX1-2 | 1-to-2 |
Zebrafish | danRer10 | ENSDARG00000006350 | nkx1.2la | 1-to-2 |
Zebrafish | danRer10 | ENSDARG00000099427 | nkx1.2lb | 1-to-2 |