Special

FBgn0002941 @ dm6

Biotype
protein_coding
Gene Symbol
slou
Description
The gene slouch is referred to in FlyBase by the symbol Dmelslou (CG6534, FBgn0002941). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:21548661..21557182. Its molecular function is described by: sequence-specific DNA binding; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: cell differentiation; muscle organ development; positive regulation of transcription by RNA polymerase II; muscle cell fate determination; negative regulation of transcription by RNA polymerase II. 14 alleles are reported. The phenotypes of these alleles manifest in: myoblast; embryonic/larval dorsal vessel; adult external thorax; ventral acute muscle 2; cardioblast. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; lethal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 06-24 hour embryonic stages.
Coordinates
chr3R:21548661-21557182:-
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)


Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000229544 NKX1-2 1-to-2
Human hg38 ENSG00000235608 NKX1-1 1-to-2
Human hg19 ENSG00000229544 NKX1-2 1-to-2
Human hg19 ENSG00000235608 NKX1-1 1-to-2
Mouse mm10 ENSMUSG00000029112 Nkx1-1 1-to-2
Mouse mm10 ENSMUSG00000048528 Nkx1-2 1-to-2
Mouse mm9 ENSMUSG00000029112 Nkx1-1 1-to-2
Mouse mm9 ENSMUSG00000048528 Nkx1-2 1-to-2
Rat rn6 ENSRNOG00000005113 Nkx1-1 1-to-2
Rat rn6 ENSRNOG00000017006 Nkx1-2 1-to-2
Cow bosTau6 ENSBTAG00000009166 GSX1 1-to-2
Cow bosTau6 ENSBTAG00000020918 NKX1-2 1-to-2
Zebrafish danRer10 ENSDARG00000006350 nkx1.2la 1-to-2
Zebrafish danRer10 ENSDARG00000099427 nkx1.2lb 1-to-2