FBgn0003339 @ dm6

protein_coding

The gene Sex combs reduced is referred to in FlyBase by the symbol DmelScr (CG1030, FBgn0003339). It is a protein_coding_gene from Dmel. It has 6 annotated transcripts and 6 polypeptides (4 unique). Gene sequence location is 3R:6823120..6849981. Its molecular function is described by: DNA-binding transcription activator activity, RNA polymerase II-specific; sequence-specific DNA binding; activating transcription factor binding; RNA polymerase II regulatory region sequence-specific DNA binding; protein homodimerization activity. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II; midgut development; salivary gland boundary specification; sex comb development; anterior/posterior pattern specification. 156 alleles are reported. The phenotypes of these alleles manifest in: embryonic tritocerebrum; episternum; embryonic abdominal segment 1; presumptive embryonic/larval peripheral nervous system; pronotum. The phenotypic classes of alleles include: wild-type; increased mortality during development; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 06-24 hour embryonic stages, during late larval stages, during early pupal stages.

chr3R:6823120-6849981:-