FBgn0015399 @ dm6
Biotype
protein_coding
Gene Symbol
kek1
Description
The gene kekkon 1 is referred to in FlyBase by the symbol Dmelkek1 (CG12283, FBgn0015399). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:12817000..12822787. Its molecular function is described by: receptor inhibitor activity; epidermal growth factor receptor binding; receptor antagonist activity. It is involved in the biological process described with: oogenesis; negative regulation of epidermal growth factor receptor signaling pathway; negative regulation of epidermal growth factor-activated receptor activity. 46 alleles are reported. The phenotypes of these alleles manifest in: visual system; somatic precursor cell; egg; adult head sensillum; egg chorion. The phenotypic classes of alleles include: visible; neuroanatomy defective; lethal - all die during P-stage; viable; lethal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed during early pupal stages.
Coordinates
chr2L:12817000-12822787:-
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
Orthologous genes[edit]
| Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
|---|---|---|---|---|
| Human | hg38 | ENSG00000040608 | RTN4R | 6-to-12 |
| Human | hg38 | ENSG00000144771 | LRTM1 | 6-to-12 |
| Human | hg38 | ENSG00000162763 | LRRC52 | 6-to-12 |
| Human | hg38 | ENSG00000254402 | LRRC24 | 6-to-12 |
| Human | hg38 | ENSG00000261594 | TPBGL | 6-to-12 |
| Human | hg19 | ENSG00000040608 | RTN4R | 6-to-12 |
| Human | hg19 | ENSG00000144771 | LRTM1 | 6-to-12 |
| Human | hg19 | ENSG00000162763 | LRRC52 | 6-to-12 |
| Mouse | mm10 | ENSMUSG00000028584 | Lrrc38 | 6-to-12 |
| Mouse | mm10 | ENSMUSG00000035274 | Tpbg | 6-to-12 |
| Mouse | mm10 | ENSMUSG00000045287 | Rtn4rl1 | 6-to-12 |
| Mouse | mm10 | ENSMUSG00000075224 | Lrrc55 | 6-to-12 |
| Mouse | mm10 | ENSMUSG00000096606 | Tpbgl | 6-to-12 |
| Mouse | mm9 | ENSMUSG00000028584 | Lrrc38 | 6-to-12 |
| Mouse | mm9 | ENSMUSG00000035274 | Tpbg | 6-to-12 |
| Mouse | mm9 | ENSMUSG00000045287 | Rtn4rl1 | 6-to-12 |
| Mouse | mm9 | ENSMUSG00000075224 | Lrrc55 | 6-to-12 |
| Rat | rn6 | ENSRNOG00000003121 | Rtn4rl1 | 6-to-6 |
| Rat | rn6 | ENSRNOG00000010694 | Tpbg | 6-to-6 |
| Rat | rn6 | ENSRNOG00000016204 | Lrrc24 | 6-to-6 |
| Rat | rn6 | ENSRNOG00000017922 | Tpbgl | 6-to-6 |
| Rat | rn6 | ENSRNOG00000021513 | Rtn4rl2 | 6-to-6 |
| Cow | bosTau6 | ENSBTAG00000012302 | RTN4RL1 | 6-to-12 |
| Cow | bosTau6 | ENSBTAG00000012621 | RTN4RL2 | 6-to-12 |
| Cow | bosTau6 | ENSBTAG00000013124 | LRTM1 | 6-to-12 |
| Cow | bosTau6 | ENSBTAG00000045734 | LRRC26 | 6-to-12 |
| Cow | bosTau6 | ENSBTAG00000046677 | RTN4R | 6-to-12 |
| Chicken | galGal4 | ENSGALG00000003443 | LRRC52 | 6-to-11 |
| Chicken | galGal4 | ENSGALG00000005404 | LRTM1 | 6-to-11 |
| Chicken | galGal4 | ENSGALG00000007732 | RTN4R | 6-to-11 |
| Chicken | galGal4 | ENSGALG00000027355 | TPBG | 6-to-11 |
| Chicken | galGal3 | ENSGALG00000003443 | LRRC52 | 6-to-11 |
| Chicken | galGal3 | ENSGALG00000005404 | LRTM1 | 6-to-11 |
| Chicken | galGal3 | ENSGALG00000007732 | RTN4R | 6-to-11 |
| Zebrafish | danRer10 | ENSDARG00000037186 | tpbgb | 6-to-18 |
| Zebrafish | danRer10 | ENSDARG00000045811 | lrtm2b | 6-to-18 |
| Zebrafish | danRer10 | ENSDARG00000052012 | rtn4rl2a | 6-to-18 |
| Zebrafish | danRer10 | ENSDARG00000075147 | lrrc38 | 6-to-18 |
| Zebrafish | danRer10 | ENSDARG00000088833 | GP1BA | 6-to-18 |