Special

FBgn0017558 @ dm6

Biotype
protein_coding
Gene Symbol
Pdk
Description
The gene Pyruvate dehydrogenase kinase is referred to in FlyBase by the symbol DmelPdk (CG8808, FBgn0017558). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 2R:9426439..9434638. Its molecular function is described by: protein serine/threonine kinase activity; protein kinase activity; pyruvate dehydrogenase (acetyl-transferring) kinase activity. It is involved in the biological process described with: pyruvate metabolic process; negative regulation of pyruvate dehydrogenase activity; glucose homeostasis. 17 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable; female semi-sterile. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 and 18-24 hour embryonic stages, during late larval stages, during late pupal stages.
Coordinates
chr2R:9426439-9434638:+
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Alternative 3'ss
0
NA
+
65.27
100
0
Alternative 3'ss
147
chr2R:9434207-9434353
+
34.73
100
0
Intron Retention
64
chr2R:9432426-9432489
+
7.51
68.97
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000067992 PDK3 1-to-1
Human hg19 ENSG00000067992 PDK3 1-to-1
Mouse mm10 ENSMUSG00000035232 Pdk3 1-to-1
Mouse mm9 ENSMUSG00000035232 Pdk3 1-to-1
Rat rn6 ENSRNOG00000001517 Pdk1 1-to-4
Rat rn6 ENSRNOG00000004172 Pdk2 1-to-4
Rat rn6 ENSRNOG00000009565 Pdk4 1-to-4
Rat rn6 ENSRNOG00000012513 Pdk3 1-to-4
Cow bosTau6 ENSBTAG00000017832 PDK3 1-to-1
Chicken galGal4 ENSGALG00000016323 PDK3 1-to-1
Chicken galGal3 ENSGALG00000016323 Q5ZLT2_CHICK 1-to-1
Zebrafish danRer10 ENSDARG00000014527 pdk3a 1-to-2
Zebrafish danRer10 ENSDARG00000099791 pdk3b 1-to-2