FBgn0017558 @ dm6
Biotype
protein_coding
Gene Symbol
Pdk
Description
The gene Pyruvate dehydrogenase kinase is referred to in FlyBase by the symbol DmelPdk (CG8808, FBgn0017558). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 2R:9426439..9434638. Its molecular function is described by: protein serine/threonine kinase activity; protein kinase activity; pyruvate dehydrogenase (acetyl-transferring) kinase activity. It is involved in the biological process described with: pyruvate metabolic process; negative regulation of pyruvate dehydrogenase activity; glucose homeostasis. 17 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable; female semi-sterile. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 and 18-24 hour embryonic stages, during late larval stages, during late pupal stages.
Coordinates
chr2R:9426439-9434638:+
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
EVENTS AND AS PROFILES[edit]
Associated events[edit]
Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Orthologous genes[edit]
Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
---|---|---|---|---|
Human | hg38 | ENSG00000067992 | PDK3 | 1-to-1 |
Human | hg19 | ENSG00000067992 | PDK3 | 1-to-1 |
Mouse | mm10 | ENSMUSG00000035232 | Pdk3 | 1-to-1 |
Mouse | mm9 | ENSMUSG00000035232 | Pdk3 | 1-to-1 |
Rat | rn6 | ENSRNOG00000001517 | Pdk1 | 1-to-4 |
Rat | rn6 | ENSRNOG00000004172 | Pdk2 | 1-to-4 |
Rat | rn6 | ENSRNOG00000009565 | Pdk4 | 1-to-4 |
Rat | rn6 | ENSRNOG00000012513 | Pdk3 | 1-to-4 |
Cow | bosTau6 | ENSBTAG00000017832 | PDK3 | 1-to-1 |
Chicken | galGal4 | ENSGALG00000016323 | PDK3 | 1-to-1 |
Chicken | galGal3 | ENSGALG00000016323 | Q5ZLT2_CHICK | 1-to-1 |
Zebrafish | danRer10 | ENSDARG00000014527 | pdk3a | 1-to-2 |
Zebrafish | danRer10 | ENSDARG00000099791 | pdk3b | 1-to-2 |