Special

FBgn0023143 @ dm6

Biotype
protein_coding
Gene Symbol
Uba1
Description
The gene Ubiquitin activating enzyme 1 is referred to in FlyBase by the symbol DmelUba1 (CG1782, FBgn0023143). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2R:9688289..9693328. Its molecular function is described by: ubiquitin activating enzyme activity. It is involved in the biological process described with 15 unique terms, many of which group under: regulation of biological process; regulation of response to stimulus; maintenance of location; cellular response to DNA damage stimulus; cell death. 54 alleles are reported. The phenotypes of these alleles manifest in: eye-antennal disc; cellular anatomical entity; central nervous system; neuron; embryonic/larval peripheral nervous system. The phenotypic classes of alleles include: lethal; phenotype; increased mortality during development; cell death defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.
Coordinates
chr2R:9688289-9693328:-
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)


Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000033178 UBA6 1-to-3
Human hg38 ENSG00000130985 UBA1 1-to-3
Human hg38 ENSG00000182179 UBA7 1-to-3
Human hg19 ENSG00000033178 UBA6 1-to-3
Human hg19 ENSG00000130985 UBA1 1-to-3
Human hg19 ENSG00000182179 UBA7 1-to-3
Mouse mm10 ENSMUSG00000001924 Uba1 1-to-4
Mouse mm10 ENSMUSG00000032596 Uba7 1-to-4
Mouse mm10 ENSMUSG00000035898 Uba6 1-to-4
Mouse mm10 ENSMUSG00000069053 Uba1y 1-to-4
Mouse mm9 ENSMUSG00000001924 Uba1 1-to-4
Mouse mm9 ENSMUSG00000032596 Uba7 1-to-4
Mouse mm9 ENSMUSG00000035898 Uba6 1-to-4
Mouse mm9 ENSMUSG00000069053 Ube1y1 1-to-4
Rat rn6 ENSRNOG00000019164 Uba1 1-to-3
Rat rn6 ENSRNOG00000029195 Uba7 1-to-3
Rat rn6 ENSRNOG00000052326 Uba1y 1-to-3
Cow bosTau6 ENSBTAG00000006837 UBA6 1-to-3
Cow bosTau6 ENSBTAG00000012335 UBA7 1-to-3
Cow bosTau6 ENSBTAG00000016764 UBA1 1-to-3
Chicken galGal4 ENSGALG00000011762 UBA6 1-to-2
Chicken galGal3 ENSGALG00000011762 UBA6 1-to-2
Zebrafish danRer10 ENSDARG00000037559 uba1 1-to-3
Zebrafish danRer10 ENSDARG00000061222 uba7 1-to-3
Zebrafish danRer10 ENSDARG00000080019 UBA6 1-to-3