FBgn0028475 @ dm6
Biotype
protein_coding
Gene Symbol
Hrd3
Description
The gene HMG-coA reductase degradation 3 is referred to in FlyBase by the symbol DmelHrd3 (CG10221, FBgn0028475). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:23754623..23758557. Its molecular function is unknown. It is involved in the biological process described with: ubiquitin-dependent ERAD pathway. 7 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: viable; some die during pupal stage; partially lethal - majority die; body color defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
Coordinates
chr3R:23754623-23758557:-
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
Orthologous genes[edit]
| Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
|---|---|---|---|---|
| Human | hg38 | ENSG00000071537 | SEL1L | 1-to-3 |
| Human | hg38 | ENSG00000091490 | SEL1L3 | 1-to-3 |
| Human | hg38 | ENSG00000101251 | SEL1L2 | 1-to-3 |
| Human | hg19 | ENSG00000071537 | SEL1L | 1-to-3 |
| Human | hg19 | ENSG00000091490 | SEL1L3 | 1-to-3 |
| Human | hg19 | ENSG00000101251 | SEL1L2 | 1-to-3 |
| Mouse | mm10 | ENSMUSG00000020964 | Sel1l | 1-to-3 |
| Mouse | mm10 | ENSMUSG00000029189 | Sel1l3 | 1-to-3 |
| Mouse | mm10 | ENSMUSG00000074764 | Sel1l2 | 1-to-3 |
| Mouse | mm9 | ENSMUSG00000020964 | Sel1l | 1-to-3 |
| Mouse | mm9 | ENSMUSG00000029189 | Sel1l3 | 1-to-3 |
| Mouse | mm9 | ENSMUSG00000074764 | Sel1l2 | 1-to-3 |
| Rat | rn6 | ENSRNOG00000004464 | Sel1l | 1-to-2 |
| Rat | rn6 | ENSRNOG00000004852 | Sel1l2 | 1-to-2 |
| Cow | bosTau6 | ENSBTAG00000002299 | SEL1L3 | 1-to-3 |
| Cow | bosTau6 | ENSBTAG00000008083 | SEL1L | 1-to-3 |
| Cow | bosTau6 | ENSBTAG00000020120 | SEL1L2 | 1-to-3 |
| Chicken | galGal4 | ENSGALG00000010581 | SEL1L | 1-to-2 |
| Chicken | galGal3 | ENSGALG00000010581 | SEL1L | 1-to-2 |
| Zebrafish | danRer10 | ENSDARG00000004581 | sel1l | 1-to-4 |
| Zebrafish | danRer10 | ENSDARG00000028784 | si:dkey-24p1.6 | 1-to-4 |
| Zebrafish | danRer10 | ENSDARG00000089049 | SEL1L3 | 1-to-4 |
| Zebrafish | danRer10 | ENSDARG00000097212 | si:dkey-24p1.6 | 1-to-4 |