Special

FBgn0029944 @ dm6

Biotype
protein_coding
Gene Symbol
Dok
Description
The gene Downstream of kinase is referred to in FlyBase by the symbol DmelDok (CG2079, FBgn0029944). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:7324214..7328806. Its molecular function is unknown. It is involved in the biological process described with: stress-activated protein kinase signaling cascade; imaginal disc-derived wing morphogenesis; dorsal closure, elongation of leading edge cells; imaginal disc fusion, thorax closure; dorsal closure. 6 alleles are reported. The phenotypes of these alleles manifest in: photoreceptor; adult thoracic segment; acellular anatomical structure; compound cell cluster organ; embryonic/larval integumentary system. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; lethal - all die before end of pupal stage; cell shape defective; lethal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
Coordinates
chrX:7324214-7328806:+
Assembly
dm6

GENOMIC BROWSER[edit]

EXPRESSION VALUES[edit]

SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)


Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000101134 DOK5 1-to-6
Human hg38 ENSG00000115325 DOK1 1-to-6
Human hg38 ENSG00000125170 DOK4 1-to-6
Human hg38 ENSG00000146094 DOK3 1-to-6
Human hg38 ENSG00000147443 DOK2 1-to-6
Human hg19 ENSG00000101134 DOK5 1-to-6
Human hg19 ENSG00000115325 DOK1 1-to-6
Human hg19 ENSG00000125170 DOK4 1-to-6
Human hg19 ENSG00000146094 DOK3 1-to-6
Human hg19 ENSG00000147443 DOK2 1-to-6
Mouse mm10 ENSMUSG00000022102 Dok2 1-to-6
Mouse mm10 ENSMUSG00000027560 Dok5 1-to-6
Mouse mm10 ENSMUSG00000035711 Dok3 1-to-6
Mouse mm10 ENSMUSG00000040631 Dok4 1-to-6
Mouse mm10 ENSMUSG00000068335 Dok1 1-to-6
Mouse mm9 ENSMUSG00000022102 Dok2 1-to-6
Mouse mm9 ENSMUSG00000027560 Dok5 1-to-6
Mouse mm9 ENSMUSG00000035711 Dok3 1-to-6
Mouse mm9 ENSMUSG00000040631 Dok4 1-to-6
Mouse mm9 ENSMUSG00000068335 Dok1 1-to-6
Rat rn6 ENSRNOG00000013196 Dok5 1-to-6
Rat rn6 ENSRNOG00000013564 Dok3 1-to-6
Rat rn6 ENSRNOG00000013922 Dok2 1-to-6
Rat rn6 ENSRNOG00000015679 Dok4 1-to-6
Rat rn6 ENSRNOG00000038190 Dok6 1-to-6
Cow bosTau6 ENSBTAG00000001857 DOK4 1-to-6
Cow bosTau6 ENSBTAG00000018579 DOK1 1-to-6
Cow bosTau6 ENSBTAG00000025401 DOK3 1-to-6
Cow bosTau6 ENSBTAG00000046957 DOK6 1-to-6
Cow bosTau6 ENSBTAG00000047975 DOK5 1-to-6
Chicken galGal4 ENSGALG00000001160 DOK4 1-to-6
Chicken galGal4 ENSGALG00000007786 DOK5 1-to-6
Chicken galGal4 ENSGALG00000013753 DOK6 1-to-6
Chicken galGal4 ENSGALG00000026914 DOK3 1-to-6
Chicken galGal3 ENSGALG00000001160 DOK4 1-to-6
Chicken galGal3 ENSGALG00000007786 DOK5 1-to-6
Chicken galGal3 ENSGALG00000013753 DOK6 1-to-6
Zebrafish danRer10 ENSDARG00000063032 dok6 1-to-5
Zebrafish danRer10 ENSDARG00000073731 DOK4 1-to-5
Zebrafish danRer10 ENSDARG00000075818 dok2 1-to-5
Zebrafish danRer10 ENSDARG00000078108 dok1a 1-to-5
Zebrafish danRer10 ENSDARG00000099177 dok1b 1-to-5
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