FBgn0030037 @ dm6
Biotype
protein_coding
Gene Symbol
CG12125
Description
The gene Mitoguardin is referred to in FlyBase by the symbol DmelMiga (CG12125, FBgn0030037). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is X:8433923..8437820. Its molecular function is unknown. It is involved in the biological process described with: regulation of mitochondrial fusion; mitochondrial fusion; mitochondrion morphogenesis; photoreceptor cell maintenance. 9 alleles are reported. The phenotypes of these alleles manifest in: eye photoreceptor cell; mitochondrion; rhabdomere of eye photoreceptor cell. The phenotypic classes of alleles include: neuroanatomy defective; lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.
Coordinates
chrX:8433923-8437820:-
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
Orthologous genes[edit]
| Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
|---|---|---|---|---|
| Human | hg38 | ENSG00000148343 | MIGA2 | 1-to-2 |
| Human | hg38 | ENSG00000180488 | MIGA1 | 1-to-2 |
| Human | hg19 | ENSG00000148343 | FAM73B | 1-to-2 |
| Human | hg19 | ENSG00000180488 | FAM73A | 1-to-2 |
| Mouse | mm10 | ENSMUSG00000026858 | Miga2 | 1-to-2 |
| Mouse | mm10 | ENSMUSG00000054942 | Miga1 | 1-to-2 |
| Mouse | mm9 | ENSMUSG00000026858 | Fam73b | 1-to-2 |
| Mouse | mm9 | ENSMUSG00000054942 | Fam73a | 1-to-2 |
| Rat | rn6 | ENSRNOG00000017513 | Miga2 | 1-to-2 |
| Rat | rn6 | ENSRNOG00000056332 | Miga1 | 1-to-2 |
| Cow | bosTau6 | ENSBTAG00000010653 | FAM73B | 1-to-2 |
| Cow | bosTau6 | ENSBTAG00000031044 | FAM73A | 1-to-2 |
| Chicken | galGal4 | ENSGALG00000008951 | FAM73A | 1-to-2 |
| Chicken | galGal3 | ENSGALG00000008951 | FAM73A | 1-to-2 |
| Zebrafish | danRer10 | ENSDARG00000020596 | fam73a | 1-to-2 |
| Zebrafish | danRer10 | ENSDARG00000089357 | fam73b | 1-to-2 |