FBgn0033935 @ dm6
Biotype
protein_coding
Gene Symbol
Sin1
Description
The gene SAPK-interacting protein 1 is referred to in FlyBase by the symbol DmelSin1 (CG10105, FBgn0033935). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:14411825..14413851. Its molecular function is described by: protein serine/threonine kinase activator activity; phosphatidylinositol-4,5-bisphosphate binding; protein kinase binding. It is involved in the biological process described with 10 unique terms, many of which group under: organelle assembly; establishment or maintenance of actin cytoskeleton polarity; synapse assembly; positive regulation of phosphorus metabolic process; neuron differentiation. 8 alleles are reported. The phenotypes of these alleles manifest in: cell projection; cytoplasmic ribonucleoprotein granule; hemocoel; embryonic/larval peripheral nervous system; neuron projection. The phenotypic classes of alleles include: viable; neuroanatomy defective; heat stress response defective; short lived; fertile. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, during late pupal stages.
Coordinates
chr2R:14411825-14413851:+
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
Orthologous genes[edit]
Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
---|---|---|---|---|
Human | hg38 | ENSG00000119487 | MAPKAP1 | 1-to-1 |
Human | hg19 | ENSG00000119487 | MAPKAP1 | 1-to-1 |
Mouse | mm10 | ENSMUSG00000038696 | Mapkap1 | 1-to-1 |
Mouse | mm9 | ENSMUSG00000038696 | Mapkap1 | 1-to-1 |
Rat | rn6 | ENSRNOG00000017583 | Mapkap1 | 1-to-2 |
Rat | rn6 | ENSRNOG00000062165 | AABR07051501.1 | 1-to-2 |
Cow | bosTau6 | ENSBTAG00000010271 | MAPKAP1 | 1-to-1 |
Chicken | galGal4 | ENSGALG00000000977 | MAPKAP1 | 1-to-1 |
Chicken | galGal3 | ENSGALG00000000977 | SIN1_CHICK | 1-to-1 |
Zebrafish | danRer10 | ENSDARG00000091777 | mapkap1 | 1-to-1 |