Special

FBgn0033935 @ dm6

Biotype
protein_coding
Gene Symbol
Sin1
Description
The gene SAPK-interacting protein 1 is referred to in FlyBase by the symbol DmelSin1 (CG10105, FBgn0033935). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:14411825..14413851. Its molecular function is described by: protein serine/threonine kinase activator activity; phosphatidylinositol-4,5-bisphosphate binding; protein kinase binding. It is involved in the biological process described with 10 unique terms, many of which group under: organelle assembly; establishment or maintenance of actin cytoskeleton polarity; synapse assembly; positive regulation of phosphorus metabolic process; neuron differentiation. 8 alleles are reported. The phenotypes of these alleles manifest in: cell projection; cytoplasmic ribonucleoprotein granule; hemocoel; embryonic/larval peripheral nervous system; neuron projection. The phenotypic classes of alleles include: viable; neuroanatomy defective; heat stress response defective; short lived; fertile. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, during late pupal stages.
Coordinates
chr2R:14411825-14413851:+
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)


Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000119487 MAPKAP1 1-to-1
Human hg19 ENSG00000119487 MAPKAP1 1-to-1
Mouse mm10 ENSMUSG00000038696 Mapkap1 1-to-1
Mouse mm9 ENSMUSG00000038696 Mapkap1 1-to-1
Rat rn6 ENSRNOG00000017583 Mapkap1 1-to-2
Rat rn6 ENSRNOG00000062165 AABR07051501.1 1-to-2
Cow bosTau6 ENSBTAG00000010271 MAPKAP1 1-to-1
Chicken galGal4 ENSGALG00000000977 MAPKAP1 1-to-1
Chicken galGal3 ENSGALG00000000977 SIN1_CHICK 1-to-1
Zebrafish danRer10 ENSDARG00000091777 mapkap1 1-to-1